Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   AMD33_RS07835 Genome accession   NZ_CP012588
Coordinates   1510296..1510589 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus strain MN-BM-A01     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1505296..1515589
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AMD33_RS07800 (AMD33_07775) - 1505699..1506142 (-) 444 WP_041829335.1 hypothetical protein -
  AMD33_RS11890 (AMD33_07780) - 1506216..1506635 (-) 420 WP_014727721.1 CPBP family intramembrane glutamic endopeptidase -
  AMD33_RS07810 (AMD33_07785) - 1506884..1507081 (-) 198 WP_014727723.1 helix-turn-helix transcriptional regulator -
  AMD33_RS07815 (AMD33_07790) - 1507330..1508523 (-) 1194 WP_014608740.1 acetate kinase -
  AMD33_RS07820 (AMD33_07795) comGH 1508579..1509535 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  AMD33_RS07825 (AMD33_07800) comGG 1509580..1509897 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG Machinery gene
  AMD33_RS07830 (AMD33_07805) comGF 1509875..1510312 (-) 438 WP_014608742.1 competence type IV pilus minor pilin ComGF Machinery gene
  AMD33_RS07835 (AMD33_07810) comGE 1510296..1510589 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  AMD33_RS07840 (AMD33_07815) comGD 1510561..1510989 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  AMD33_RS07845 (AMD33_07820) comGC 1510949..1511275 (-) 327 WP_014727724.1 competence type IV pilus major pilin ComGC Machinery gene
  AMD33_RS07850 (AMD33_07825) comGB 1511272..1512372 (-) 1101 WP_116920398.1 competence type IV pilus assembly protein ComGB Machinery gene
  AMD33_RS07855 (AMD33_07830) comGA/cglA/cilD 1512254..1513195 (-) 942 WP_014727726.1 competence type IV pilus ATPase ComGA Machinery gene
  AMD33_RS07860 (AMD33_07835) - 1513276..1513638 (-) 363 WP_014608746.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=134831 AMD33_RS07835 WP_011226625.1 1510296..1510589(-) (comGE) [Streptococcus thermophilus strain MN-BM-A01]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=134831 AMD33_RS07835 WP_011226625.1 1510296..1510589(-) (comGE) [Streptococcus thermophilus strain MN-BM-A01]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361