Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   AMM49_RS03535 Genome accession   NZ_CP012480
Coordinates   647529..648314 (+) Length   261 a.a.
NCBI ID   WP_000825431.1    Uniprot ID   Q8E0P2
Organism   Streptococcus agalactiae strain NGBS128     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 642529..653314
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AMM49_RS03510 (AMM49_03495) - 643646..644440 (+) 795 WP_001869075.1 ABC transporter permease -
  AMM49_RS11205 (AMM49_03500) - 644541..644669 (+) 129 WP_000962057.1 hypothetical protein -
  AMM49_RS03520 (AMM49_03505) - 644678..644998 (+) 321 WP_001865677.1 hypothetical protein -
  AMM49_RS03525 (AMM49_03510) - 645095..645766 (+) 672 WP_000891267.1 ATP-binding cassette domain-containing protein -
  AMM49_RS03530 (AMM49_03515) - 645823..647268 (-) 1446 WP_000750933.1 FAD/NAD(P)-binding protein -
  AMM49_RS03535 (AMM49_03520) endA 647529..648314 (+) 786 WP_000825431.1 DNA/RNA non-specific endonuclease Machinery gene
  AMM49_RS03540 (AMM49_03525) - 648392..649030 (-) 639 WP_000478531.1 VTT domain-containing protein -
  AMM49_RS03545 (AMM49_03530) - 649247..649903 (+) 657 WP_000121094.1 ABC transporter ATP-binding protein -
  AMM49_RS03550 (AMM49_03535) - 649900..650673 (+) 774 WP_000011926.1 ABC transporter permease -
  AMM49_RS03555 (AMM49_03540) - 650837..651655 (+) 819 WP_000601007.1 hypothetical protein -
  AMM49_RS03560 (AMM49_03545) - 651692..652576 (-) 885 WP_000354843.1 LysR family transcriptional regulator -

Sequence

Protein


Download         Length: 261 a.a.        Molecular weight: 29424.86 Da        Isoelectric Point: 8.9989

>NTDB_id=133744 AMM49_RS03535 WP_000825431.1 647529..648314(+) (endA) [Streptococcus agalactiae strain NGBS128]
MKRLHKLFITVIATLGMLGVMTFGLPTQPQNVTPIVHADVNSSVDTSQEFQNNLKNAIGNLPFQYVNGIYELNNNQTNLN
ADVNVKAYVQNTIDNQQRLSTANAMLDRTIRQYQNRRDTTLPDANWKPLGWHQVATNDHYGHAVDKGHLIAYALAGNFKG
WDASVSNPQNVVTQTAHSNQSNQKINRGQNYYESLVRKAVDQNKRVRYRVTPLYRNDTDLVPFAMHLEAKSQDGTLEFNV
AIPNTQASYTMDYATGEITLN

Nucleotide


Download         Length: 786 bp        

>NTDB_id=133744 AMM49_RS03535 WP_000825431.1 647529..648314(+) (endA) [Streptococcus agalactiae strain NGBS128]
ATGAAAAGATTACATAAACTGTTTATAACCGTAATTGCTACATTAGGTATGTTGGGGGTAATGACCTTTGGTCTTCCAAC
GCAGCCGCAAAACGTAACGCCGATAGTACATGCTGATGTCAATTCATCTGTTGATACGAGCCAGGAATTTCAAAATAATT
TAAAAAATGCTATTGGTAACCTACCATTTCAATATGTTAATGGTATTTATGAATTAAATAATAATCAGACAAATTTAAAT
GCTGATGTCAATGTTAAAGCGTATGTTCAAAATACAATTGACAATCAACAAAGACTATCAACTGCTAATGCAATGCTTGA
TAGAACCATTCGTCAATATCAAAATCGCAGAGATACCACTCTTCCCGATGCAAATTGGAAACCATTAGGTTGGCATCAAG
TAGCTACTAATGACCATTATGGGCATGCAGTCGACAAGGGGCATTTAATTGCCTATGCTTTAGCTGGAAATTTCAAAGGT
TGGGATGCTTCCGTGTCAAATCCTCAAAATGTTGTCACACAAACAGCTCATTCCAACCAATCAAATCAAAAAATCAATCG
TGGACAAAATTATTATGAAAGCTTAGTTCGTAAGGCGGTTGACCAAAACAAACGTGTTCGTTACCGTGTAACTCCATTGT
ACCGTAATGATACTGATTTAGTTCCATTTGCAATGCACCTAGAAGCTAAATCACAAGATGGCACATTAGAATTTAATGTT
GCTATTCCAAACACACAAGCATCATACACTATGGATTATGCAACAGGAGAAATAACACTAAATTAA

Domains

Predicted by InterProScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(77-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8E0P2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

51.515

75.862

0.391
  endA Streptococcus pneumoniae D39

51.515

75.862

0.391
  endA Streptococcus pneumoniae R6

51.515

75.862

0.391
  endA Streptococcus pneumoniae TIGR4

51.515

75.862

0.391