Detailed information NTG0130291

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: SAHC1340_RS07135
• Genome accession: NZ_CP012011
• Coordinates: 1395617..1396390 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain HC1340
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1390617..1401390

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAHC1340_RS07115 (SAHC1340_02089)	trmFO	1390961..1392268 (+)	1308	WP_000195254.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
SAHC1340_RS07120 (SAHC1340_02090)	xerC	1392685..1393581 (+)	897	WP_001015597.1	tyrosine recombinase XerC	-
SAHC1340_RS07125 (SAHC1340_02091)	hslV	1393578..1394123 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
SAHC1340_RS07130 (SAHC1340_02092)	hslU	1394189..1395592 (+)	1404	WP_000379054.1	ATP-dependent protease ATPase subunit HslU	-
SAHC1340_RS07135 (SAHC1340_02093)	codY	1395617..1396390 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
SAHC1340_RS07140	-	1396441..1396533 (+)	93	WP_001790530.1	hypothetical protein	-
SAHC1340_RS07145 (SAHC1340_02095)	rpsB	1396732..1397499 (+)	768	WP_000268484.1	30S ribosomal protein S2	-
SAHC1340_RS07150	-	1397533..1397646 (+)	114	WP_001789890.1	hypothetical protein	-
SAHC1340_RS07155 (SAHC1340_02096)	tsf	1397681..1398562 (+)	882	WP_000201387.1	translation elongation factor Ts	-
SAHC1340_RS07160 (SAHC1340_02097)	pyrH	1398699..1399421 (+)	723	WP_020444699.1	UMP kinase	-
SAHC1340_RS07165 (SAHC1340_02098)	frr	1399440..1399994 (+)	555	WP_001280006.1	ribosome recycling factor	-
SAHC1340_RS07170 (SAHC1340_02099)	-	1400367..1401137 (+)	771	WP_000473701.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=130291 SAHC1340_RS07135 WP_000055337.1 1395617..1396390(+) (codY) [Staphylococcus aureus strain HC1340]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=130291 SAHC1340_RS07135 WP_000055337.1 1395617..1396390(+) (codY) [Staphylococcus aureus strain HC1340]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGGGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428