Detailed information NTG0127975

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: SpyM6JRS4_RS09570
• Genome accession: NZ_CP011414
• Coordinates: 561383..562249 (+)
• Length: 288 a.a.
• NCBI ID: WP_011184363.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes JRS4
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 556383..567249

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SpyM6JRS4_RS02850 (SpyM6JRS4_02845)	-	556424..557299 (+)	876	WP_002985236.1	F0F1 ATP synthase subunit gamma	-
SpyM6JRS4_RS02855 (SpyM6JRS4_02850)	atpD	557461..558867 (+)	1407	WP_011017611.1	F0F1 ATP synthase subunit beta	-
SpyM6JRS4_RS02860 (SpyM6JRS4_02855)	-	558880..559296 (+)	417	WP_002985233.1	F0F1 ATP synthase subunit epsilon	-
SpyM6JRS4_RS02865 (SpyM6JRS4_02860)	-	559583..559819 (+)	237	WP_280529076.1	DUF1146 family protein	-
SpyM6JRS4_RS02870 (SpyM6JRS4_02865)	murA	559884..561155 (+)	1272	WP_002994428.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
SpyM6JRS4_RS02875 (SpyM6JRS4_02870)	-	561159..561347 (+)	189	WP_011017613.1	DNA-directed RNA polymerase subunit beta	-
SpyM6JRS4_RS09570 (SpyM6JRS4_02875)	endA	561383..562249 (+)	867	WP_011184363.1	DNA/RNA non-specific endonuclease	Machinery gene
SpyM6JRS4_RS02885 (SpyM6JRS4_02880)	pheS	562532..563575 (+)	1044	WP_003057440.1	phenylalanine--tRNA ligase subunit alpha	-
SpyM6JRS4_RS02890 (SpyM6JRS4_02885)	pheT	563785..566190 (+)	2406	WP_023078221.1	phenylalanine--tRNA ligase subunit beta	-
SpyM6JRS4_RS02895 (SpyM6JRS4_02890)	-	566302..566679 (+)	378	WP_021340346.1	OsmC family protein	-
SpyM6JRS4_RS02900 (SpyM6JRS4_02895)	-	566672..567058 (+)	387	WP_002990406.1	YbgA family protein	-

Sequence

Protein

• Length: 288 a.a.
• Molecular weight: 32111.62 Da
• Isoelectric Point: 10.4010

>NTDB_id=127975 SpyM6JRS4_RS09570 WP_011184363.1 561383..562249(+) (endA) [Streptococcus pyogenes JRS4]
MLAKKKRKRVLNSFLLILLVLGSNCLAKSDFIASNHPIKQLYQTLVGEKKKSLLTHNNLPADVPTEALAASVLTPSIKKQ
LGPDVQWNGAGAYIINRNKTDLNAKVASLPYANNETKWVQEQKVPKRANALLTKSTRQYRNRYQTDNAYRNFKPAGWHRL
HRLKGSYDHAVDRGHLLGYALVGGLKGLDASTGNPDNIATQLSWANQANKPYSTGQNYYEGLVCRALDKGHRVRYRVTLL
YDGDNLLASGSHLEAKSSDDSLTFNVFVPNVQPGLTVDYRTRQIAINL

Nucleotide

• Length: 867 bp

>NTDB_id=127975 SpyM6JRS4_RS09570 WP_011184363.1 561383..562249(+) (endA) [Streptococcus pyogenes JRS4]
ATGTTAGCAAAGAAAAAACGAAAAAGGGTGCTTAATTCCTTCTTATTGATTTTGTTAGTGTTGGGGTCTAACTGCCTTGC
TAAGAGTGATTTCATAGCTAGCAATCACCCTATCAAGCAACTTTATCAGACTCTTGTTGGGGAGAAGAAAAAATCATTAC
TCACACATAATAATTTGCCCGCTGATGTTCCCACAGAAGCTCTGGCGGCATCGGTATTAACACCATCAATCAAAAAGCAA
CTAGGTCCAGATGTTCAGTGGAATGGAGCAGGCGCCTATATTATCAACAGGAACAAAACAGATTTAAATGCTAAGGTAGC
CAGTCTGCCCTATGCCAACAATGAAACCAAATGGGTGCAAGAGCAAAAGGTTCCTAAAAGAGCTAATGCCTTACTTACTA
AGTCGACACGACAGTATCGAAATCGCTATCAAACGGACAATGCTTATCGTAACTTTAAGCCAGCAGGTTGGCACCGATTG
CACCGCTTAAAAGGAAGTTATGATCACGCGGTTGATAGAGGGCATTTGCTAGGTTATGCTTTAGTTGGTGGACTGAAAGG
TTTAGATGCTTCTACCGGTAATCCTGATAATATTGCCACTCAACTAAGTTGGGCTAATCAAGCAAATAAACCCTACTCGA
CAGGTCAGAATTACTATGAAGGTTTAGTATGTCGTGCTTTGGATAAGGGGCATCGCGTCCGCTACCGTGTCACCCTACTT
TATGATGGTGATAATCTACTAGCCAGCGGTAGCCATTTGGAGGCTAAATCCTCTGATGACAGCTTGACTTTTAACGTGTT
TGTTCCAAATGTCCAACCAGGATTGACCGTTGACTATAGGACGAGACAAATAGCTATCAATCTCTAA

Domains

Predicted by InterProScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (111-246)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	57.806	82.292	0.476
endA	Streptococcus pneumoniae D39	57.806	82.292	0.476
endA	Streptococcus pneumoniae R6	57.806	82.292	0.476
endA	Streptococcus pneumoniae TIGR4	57.806	82.292	0.476