Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   ID09_RS06060 Genome accession   NZ_CP008921
Coordinates   1242132..1242971 (-) Length   279 a.a.
NCBI ID   WP_024381398.1    Uniprot ID   A0A075SE64
Organism   Streptococcus suis 6407     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1237132..1247971
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ID09_RS06045 (ID09_06215) uidA 1237492..1239291 (-) 1800 WP_024381396.1 beta-glucuronidase -
  ID09_RS06050 (ID09_06220) - 1239308..1240336 (-) 1029 WP_024390544.1 sugar kinase -
  ID09_RS06055 (ID09_06225) - 1240392..1241945 (-) 1554 WP_013730405.1 MFS transporter -
  ID09_RS06060 (ID09_06230) endA 1242132..1242971 (-) 840 WP_024381398.1 DNA/RNA non-specific endonuclease Machinery gene
  ID09_RS06065 (ID09_06235) - 1243001..1243192 (-) 192 WP_024381399.1 DNA-directed RNA polymerase subunit beta -
  ID09_RS06070 (ID09_06240) murA 1243185..1244468 (-) 1284 WP_002936006.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  ID09_RS06075 (ID09_06245) - 1244492..1244716 (-) 225 WP_012775178.1 DUF1146 family protein -
  ID09_RS06080 (ID09_06250) - 1244776..1245192 (-) 417 WP_002936007.1 F0F1 ATP synthase subunit epsilon -
  ID09_RS06085 (ID09_06255) atpD 1245202..1246608 (-) 1407 WP_002936008.1 F0F1 ATP synthase subunit beta -
  ID09_RS06090 (ID09_06260) - 1246628..1247506 (-) 879 WP_002936012.1 F0F1 ATP synthase subunit gamma -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 30204.40 Da        Isoelectric Point: 6.2370

>NTDB_id=125702 ID09_RS06060 WP_024381398.1 1242132..1242971(-) (endA) [Streptococcus suis 6407]
MAKKNVKKQAMSLLSLLATIVVVAGGYLLSDNKSSNLADYSYYVNQSKASEGTPNQELASSVLTEDVKKQLGNSIEWNSA
GAFIINGNQTDLDASVASVPYGDNKTKTVQGETVPTVANALLAKSTRQYKDREETGNGRTSWTPAGWHQIHDLTGEYDHA
VDRGHLLGYALIGGLSGFDASTSNPKNIAVQTAWSNQANDQTSTGQNYFESQIRRALDKNKRVRYRVTLVYAESEDLVPV
GSHLEAKAADGSLEFNVFVPNVQSGLSINYHSGEIAVNQ

Nucleotide


Download         Length: 840 bp        

>NTDB_id=125702 ID09_RS06060 WP_024381398.1 1242132..1242971(-) (endA) [Streptococcus suis 6407]
ATGGCGAAGAAAAATGTAAAAAAACAAGCAATGAGTCTGCTCAGCTTATTGGCTACGATTGTTGTAGTAGCGGGTGGCTA
TCTTTTAAGTGATAACAAGAGCAGTAACCTTGCTGATTATTCCTATTATGTCAATCAGTCTAAGGCAAGTGAAGGCACAC
CTAATCAGGAACTGGCTAGTTCGGTATTGACAGAAGATGTAAAAAAGCAACTGGGGAATTCGATTGAATGGAATAGCGCT
GGAGCATTTATTATTAACGGTAATCAAACGGATTTAGATGCATCGGTTGCCAGTGTTCCTTATGGTGATAATAAGACAAA
GACAGTCCAGGGAGAGACGGTTCCAACCGTAGCCAATGCGCTTTTAGCTAAATCTACACGTCAGTATAAGGATCGTGAAG
AAACAGGAAATGGTCGAACTTCTTGGACACCTGCGGGTTGGCATCAAATCCATGATTTAACTGGAGAATATGACCATGCA
GTGGACCGTGGTCACCTCCTAGGTTATGCTTTGATTGGTGGATTGTCTGGCTTCGATGCTTCAACCAGCAATCCTAAGAA
TATTGCAGTTCAAACAGCTTGGTCCAACCAAGCTAACGACCAAACTTCAACTGGGCAAAATTATTTTGAAAGTCAGATTC
GGCGTGCCTTGGATAAAAATAAGCGTGTCCGCTATCGTGTGACCTTGGTGTATGCTGAGAGTGAAGACCTTGTTCCTGTC
GGAAGTCATCTAGAGGCAAAAGCAGCAGATGGTAGCCTAGAGTTCAATGTGTTCGTTCCAAATGTGCAGAGTGGTCTCAG
TATCAACTATCATAGTGGGGAAATTGCAGTAAATCAATAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(81-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A075SE64

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

69.492

84.588

0.588
  endA Streptococcus pneumoniae D39

69.492

84.588

0.588
  endA Streptococcus pneumoniae R6

69.492

84.588

0.588
  endA Streptococcus pneumoniae TIGR4

69.492

84.588

0.588

Multiple sequence alignment