Detailed information NTG0125034

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: CUGBS98_RS03455
• Genome accession: NZ_CP010875
• Coordinates: 638497..639282 (+)
• Length: 261 a.a.
• NCBI ID: WP_000825431.1
• Uniprot ID: Q8E0P2
• Organism: Streptococcus agalactiae strain CU_GBS_98
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 633497..644282

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CUGBS98_RS10800 (CUGBS98_00686)	-	634617..635060 (+)	444	WP_001048166.1	hypothetical protein	-
CUGBS98_RS10805 (CUGBS98_00687)	-	635145..635411 (+)	267	WP_001865676.1	hypothetical protein	-
CUGBS98_RS10810	-	635512..635643 (+)	132	WP_017647804.1	hypothetical protein	-
CUGBS98_RS10815 (CUGBS98_00688)	-	635652..635972 (+)	321	WP_001865677.1	hypothetical protein	-
CUGBS98_RS03445 (CUGBS98_00689)	-	636069..636740 (+)	672	WP_000891267.1	ABC transporter ATP-binding protein	-
CUGBS98_RS03450 (CUGBS98_00690)	-	636797..638236 (-)	1440	WP_017647803.1	FAD/NAD(P)-binding protein	-
CUGBS98_RS03455 (CUGBS98_00691)	endA	638497..639282 (+)	786	WP_000825431.1	DNA/RNA non-specific endonuclease	Machinery gene
CUGBS98_RS03460 (CUGBS98_00692)	-	639360..639998 (-)	639	WP_000478529.1	VTT domain-containing protein	-
CUGBS98_RS03465 (CUGBS98_00693)	-	640215..640871 (+)	657	WP_000121094.1	ATP-binding cassette domain-containing protein	-
CUGBS98_RS03470 (CUGBS98_00694)	fetB	640868..641641 (+)	774	WP_000011926.1	iron export ABC transporter permease subunit FetB	-
CUGBS98_RS03475 (CUGBS98_00695)	-	641805..642623 (+)	819	WP_000601007.1	hypothetical protein	-
CUGBS98_RS03480 (CUGBS98_00696)	-	642660..643544 (-)	885	WP_000354840.1	LysR family transcriptional regulator	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 29424.86 Da
• Isoelectric Point: 8.9989

>NTDB_id=125034 CUGBS98_RS03455 WP_000825431.1 638497..639282(+) (endA) [Streptococcus agalactiae strain CU_GBS_98]
MKRLHKLFITVIATLGMLGVMTFGLPTQPQNVTPIVHADVNSSVDTSQEFQNNLKNAIGNLPFQYVNGIYELNNNQTNLN
ADVNVKAYVQNTIDNQQRLSTANAMLDRTIRQYQNRRDTTLPDANWKPLGWHQVATNDHYGHAVDKGHLIAYALAGNFKG
WDASVSNPQNVVTQTAHSNQSNQKINRGQNYYESLVRKAVDQNKRVRYRVTPLYRNDTDLVPFAMHLEAKSQDGTLEFNV
AIPNTQASYTMDYATGEITLN

Nucleotide

• Length: 786 bp

>NTDB_id=125034 CUGBS98_RS03455 WP_000825431.1 638497..639282(+) (endA) [Streptococcus agalactiae strain CU_GBS_98]
ATGAAAAGATTACATAAACTGTTTATAACCGTAATTGCTACATTAGGTATGTTGGGGGTAATGACCTTTGGTCTTCCAAC
GCAGCCGCAAAACGTAACGCCGATAGTACATGCTGATGTCAATTCATCTGTTGATACGAGCCAGGAATTTCAAAATAATT
TAAAAAATGCTATTGGTAACCTACCATTTCAATATGTTAATGGTATTTATGAATTAAATAATAATCAGACAAATTTAAAT
GCTGATGTCAATGTTAAAGCGTATGTTCAAAATACAATTGACAATCAACAAAGACTATCAACTGCTAATGCAATGCTTGA
TAGAACCATTCGTCAATATCAAAATCGCAGAGATACCACTCTTCCCGATGCAAATTGGAAACCATTAGGTTGGCATCAAG
TAGCTACTAATGACCATTATGGACATGCAGTCGACAAGGGGCATTTAATTGCCTATGCTTTAGCTGGAAATTTCAAAGGT
TGGGATGCTTCCGTGTCAAATCCTCAAAATGTTGTCACACAAACAGCTCATTCCAACCAATCAAATCAAAAAATCAATCG
TGGACAAAATTATTATGAAAGCTTAGTTCGTAAGGCGGTTGACCAAAACAAACGTGTTCGTTACCGTGTAACTCCATTGT
ACCGTAATGATACTGATTTAGTTCCATTTGCAATGCACCTAGAAGCTAAATCACAAGATGGCACATTAGAATTTAATGTT
GCTATTCCAAACACACAAGCATCATACACTATGGATTATGCAACAGGAGAAATAACACTAAATTAA

Domains

Predicted by InterProScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (77-235)

3D structure

• AlphaFold DB: Q8E0P2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	51.515	75.862	0.391
endA	Streptococcus pneumoniae D39	51.515	75.862	0.391
endA	Streptococcus pneumoniae R6	51.515	75.862	0.391
endA	Streptococcus pneumoniae TIGR4	51.515	75.862	0.391