Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   HYU01_RS19175 Genome accession   NZ_CP008846
Coordinates   3628308..3629087 (-) Length   259 a.a.
NCBI ID   WP_038414191.1    Uniprot ID   -
Organism   Bacillus anthracis strain HYU01     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3593986..3667911 3628308..3629087 within 0


Gene organization within MGE regions


Location: 3593986..3667911
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HYU01_RS19020 (HYU01_19225) - 3594329..3595999 (-) 1671 WP_000823085.1 ribonuclease J -
  HYU01_RS19030 (HYU01_19235) dapA 3596765..3597643 (-) 879 WP_000564767.1 4-hydroxy-tetrahydrodipicolinate synthase -
  HYU01_RS19035 (HYU01_19240) dapG 3597655..3598887 (-) 1233 WP_000692470.1 aspartate kinase -
  HYU01_RS19040 (HYU01_19245) asd 3598911..3599957 (-) 1047 WP_000414849.1 aspartate-semialdehyde dehydrogenase -
  HYU01_RS19045 (HYU01_19250) dpaB 3600108..3600707 (-) 600 WP_001049484.1 dipicolinate synthase subunit B -
  HYU01_RS19050 (HYU01_19255) dpaA 3600704..3601606 (-) 903 WP_000954726.1 dipicolinic acid synthetase subunit A -
  HYU01_RS19055 (HYU01_19260) - 3601881..3602132 (-) 252 WP_001239752.1 YlmC/YmxH family sporulation protein -
  HYU01_RS19060 (HYU01_19265) - 3602259..3603500 (-) 1242 WP_000592993.1 pitrilysin family protein -
  HYU01_RS19065 (HYU01_19270) - 3603587..3604486 (-) 900 WP_000647529.1 polysaccharide deacetylase family protein -
  HYU01_RS19070 (HYU01_19275) pnp 3604638..3606776 (-) 2139 WP_000076750.1 polyribonucleotide nucleotidyltransferase -
  HYU01_RS19075 (HYU01_19280) rpsO 3606937..3607206 (-) 270 WP_001229392.1 30S ribosomal protein S15 -
  HYU01_RS19080 (HYU01_19285) ribF 3607307..3608278 (-) 972 WP_000766711.1 bifunctional riboflavin kinase/FAD synthetase -
  HYU01_RS19085 (HYU01_19290) truB 3608322..3609245 (-) 924 WP_000399357.1 tRNA pseudouridine(55) synthase TruB -
  HYU01_RS19090 (HYU01_19295) rbfA 3609332..3609688 (-) 357 WP_000776441.1 30S ribosome-binding factor RbfA -
  HYU01_RS19095 (HYU01_19300) - 3609704..3609985 (-) 282 WP_000582364.1 DUF503 domain-containing protein -
  HYU01_RS19100 (HYU01_19305) infB 3609982..3612042 (-) 2061 WP_000036340.1 translation initiation factor IF-2 -
  HYU01_RS19105 (HYU01_19310) - 3612047..3612358 (-) 312 WP_001286523.1 YlxQ family RNA-binding protein -
  HYU01_RS19110 (HYU01_19315) rnpM 3612359..3612631 (-) 273 WP_000071128.1 RNase P modulator RnpM -
  HYU01_RS19115 (HYU01_19320) nusA 3612643..3613749 (-) 1107 WP_000102606.1 transcription termination factor NusA -
  HYU01_RS19120 (HYU01_19325) rimP 3613767..3614237 (-) 471 WP_000359097.1 ribosome maturation factor RimP -
  HYU01_RS19125 (HYU01_19330) - 3614570..3618871 (-) 4302 WP_000059985.1 PolC-type DNA polymerase III -
  HYU01_RS19130 (HYU01_19335) - 3618996..3620696 (-) 1701 WP_000814312.1 proline--tRNA ligase -
  HYU01_RS19135 (HYU01_19340) rseP 3620806..3622062 (-) 1257 WP_001090228.1 RIP metalloprotease RseP -
  HYU01_RS19140 (HYU01_19345) dxr 3622079..3623221 (-) 1143 WP_000790359.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  HYU01_RS19145 (HYU01_19350) cdsA 3623245..3624036 (-) 792 WP_000813581.1 phosphatidate cytidylyltransferase -
  HYU01_RS19150 (HYU01_19355) uppS 3624054..3624830 (-) 777 WP_000971301.1 isoprenyl transferase -
  HYU01_RS19155 (HYU01_19360) frr 3624916..3625473 (-) 558 WP_000531503.1 ribosome recycling factor -
  HYU01_RS19160 (HYU01_19365) pyrH 3625476..3626198 (-) 723 WP_000042663.1 UMP kinase -
  HYU01_RS19165 (HYU01_19370) tsf 3626265..3627152 (-) 888 WP_001018581.1 translation elongation factor Ts -
  HYU01_RS19170 (HYU01_19375) rpsB 3627256..3627957 (-) 702 WP_000111483.1 30S ribosomal protein S2 -
  HYU01_RS19175 (HYU01_19380) codY 3628308..3629087 (-) 780 WP_038414191.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  HYU01_RS19180 (HYU01_19385) hslU 3629165..3630556 (-) 1392 WP_025440291.1 ATP-dependent protease ATPase subunit HslU -
  HYU01_RS19185 (HYU01_19390) hslV 3630579..3631121 (-) 543 WP_000526272.1 ATP-dependent protease proteolytic subunit HslV -
  HYU01_RS19190 (HYU01_19395) xerC 3631164..3632063 (-) 900 WP_001101226.1 tyrosine recombinase XerC -
  HYU01_RS19195 (HYU01_19400) trmFO 3632129..3633433 (-) 1305 WP_001991958.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  HYU01_RS19200 (HYU01_19405) topA 3633484..3635562 (-) 2079 WP_001286969.1 type I DNA topoisomerase -
  HYU01_RS19205 (HYU01_19410) dprA 3635707..3636455 (-) 749 Protein_3697 DNA-processing protein DprA -
  HYU01_RS19210 (HYU01_19415) sucD 3636663..3637565 (-) 903 WP_000115178.1 succinate--CoA ligase subunit alpha -
  HYU01_RS19215 (HYU01_19420) sucC 3637586..3638746 (-) 1161 WP_001020786.1 ADP-forming succinate--CoA ligase subunit beta -
  HYU01_RS19220 (HYU01_19425) rnhB 3638940..3639713 (-) 774 WP_001174712.1 ribonuclease HII -
  HYU01_RS19225 (HYU01_19430) ylqF 3639765..3640655 (-) 891 WP_000236707.1 ribosome biogenesis GTPase YlqF -
  HYU01_RS19230 (HYU01_19435) lepB 3640676..3641227 (-) 552 WP_000711857.1 signal peptidase I -
  HYU01_RS19235 (HYU01_19440) rplS 3641329..3641673 (-) 345 WP_001186516.1 50S ribosomal protein L19 -
  HYU01_RS19240 (HYU01_19445) trmD 3641820..3642554 (-) 735 WP_000686892.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  HYU01_RS19245 (HYU01_19450) rimM 3642554..3643069 (-) 516 WP_000170269.1 ribosome maturation factor RimM -
  HYU01_RS19250 (HYU01_19455) - 3643190..3643417 (-) 228 WP_000737398.1 KH domain-containing protein -
  HYU01_RS19255 (HYU01_19460) rpsP 3643432..3643704 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  HYU01_RS19260 (HYU01_19465) ffh 3643805..3645154 (-) 1350 WP_000863456.1 signal recognition particle protein -
  HYU01_RS19265 (HYU01_19470) - 3645167..3645499 (-) 333 WP_000891062.1 putative DNA-binding protein -
  HYU01_RS19270 (HYU01_19475) ftsY 3645633..3646622 (-) 990 WP_000007650.1 signal recognition particle-docking protein FtsY -
  HYU01_RS19275 (HYU01_19480) smc 3646638..3650207 (-) 3570 WP_000478986.1 chromosome segregation protein SMC -
  HYU01_RS19280 (HYU01_19485) rncS 3650354..3651091 (-) 738 WP_001146873.1 ribonuclease III -
  HYU01_RS19285 (HYU01_19490) acpP 3651150..3651383 (-) 234 WP_000786062.1 acyl carrier protein -
  HYU01_RS19290 (HYU01_19495) fabG 3651453..3652193 (-) 741 WP_000911782.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  HYU01_RS19295 (HYU01_19500) fabD 3652193..3653137 (-) 945 WP_000516948.1 ACP S-malonyltransferase -
  HYU01_RS19300 (HYU01_19505) plsX 3653152..3654144 (-) 993 WP_000684111.1 phosphate acyltransferase PlsX -
  HYU01_RS19305 (HYU01_19510) fapR 3654141..3654734 (-) 594 WP_000747352.1 transcription factor FapR -
  HYU01_RS19310 (HYU01_19515) recG 3654823..3656871 (-) 2049 WP_001006884.1 ATP-dependent DNA helicase RecG -
  HYU01_RS19315 (HYU01_19520) - 3657161..3658837 (-) 1677 WP_000027136.1 DAK2 domain-containing protein -
  HYU01_RS19320 (HYU01_19525) - 3658860..3659222 (-) 363 WP_000021109.1 Asp23/Gls24 family envelope stress response protein -
  HYU01_RS19325 (HYU01_19530) rpmB 3659601..3659789 (+) 189 WP_000124778.1 50S ribosomal protein L28 -
  HYU01_RS19330 spoVM 3659863..3659943 (-) 81 WP_001213599.1 stage V sporulation protein SpoVM -
  HYU01_RS19335 (HYU01_19540) - 3660010..3660690 (-) 681 WP_025388434.1 thiamine diphosphokinase -
  HYU01_RS19340 (HYU01_19545) rpe 3660790..3661434 (-) 645 WP_000589966.1 ribulose-phosphate 3-epimerase -
  HYU01_RS19345 (HYU01_19550) rsgA 3661437..3662318 (-) 882 WP_001113935.1 ribosome small subunit-dependent GTPase A -
  HYU01_RS19350 (HYU01_19555) prkC 3662587..3664560 (-) 1974 WP_000904759.1 serine/threonine protein kinase PrkC -
  HYU01_RS19355 (HYU01_19560) - 3664569..3665321 (-) 753 WP_000648699.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  HYU01_RS19360 (HYU01_19565) rlmN 3665326..3666414 (-) 1089 WP_000450543.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  HYU01_RS19365 (HYU01_19570) rsmB 3666419..3667753 (-) 1335 WP_001249680.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28804.07 Da        Isoelectric Point: 4.7947

>NTDB_id=124722 HYU01_RS19175 WP_038414191.1 3628308..3629087(-) (codY) [Bacillus anthracis strain HYU01]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKTVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLHELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=124722 HYU01_RS19175 WP_038414191.1 3628308..3629087(-) (codY) [Bacillus anthracis strain HYU01]
ATGGAATTATTAGCAAAAACAAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCGAACGTATTCGTAGTAAGTCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATCGAGAATGAGCGTATGAAACAAATGCTTGCAGAACGTCAATTCCCAGAAGAGTATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTAAACAGTGCTTACACAGCATTCCCAGTAGAAAATAAAGAATTATTTGG
TCAAGGTTTAACTACAATCGTACCGATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTTTTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATTCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATTTTACGTGAAAAAGCAGAA
GAAATCGAAGAAGAAGCACGTAGCAAAACTGTTGTTCAAATGGCGATCAGCTCATTATCTTACAGTGAATTAGAAGCAAT
CGAGCACATCTTCGAAGAATTAAACGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGACCGCGTAGGAATCACTC
GTTCGGTAATCGTAAATGCACTTCGTAAATTAGAAAGTGCTGGTGTAATTGAGTCGCGTTCTTTAGGTATGAAAGGAACA
TACATTAAAGTATTAAACGACAAATTCTTACATGAACTTGCTAAATTAAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY helix-turn-helix domain (HTH_CodY)

(198-255)

CodY GAF-like domain (CodY)

(2-178)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

80.695

100

0.807
  codY Lactococcus lactis subsp. lactis strain DGCC12653

47.059

98.456

0.463

Multiple sequence alignment