Detailed information NTG0122311

Bioinformatically predicted

Overview

• Name: recD2
• Type: Machinery gene
• Locus tag: EP54_RS08540
• Genome accession: NZ_CP007670
• Coordinates: 1706638..1709115 (-)
• Length: 825 a.a.
• NCBI ID: WP_001283311.1
• Uniprot ID: A0A0D6H7H2
• Organism: Staphylococcus aureus strain M121
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1701638..1714115

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EP54_RS08515 (EP54_08120)	-	1701664..1702302 (-)	639	WP_000342266.1	O-methyltransferase	-
EP54_RS08520 (EP54_08125)	-	1702587..1702895 (-)	309	WP_000134779.1	DUF1292 domain-containing protein	-
EP54_RS08525 (EP54_08130)	ruvX	1702910..1703338 (-)	429	WP_000939059.1	Holliday junction resolvase RuvX	-
EP54_RS08530 (EP54_08135)	-	1703342..1703602 (-)	261	WP_000426912.1	IreB family regulatory phosphoprotein	-
EP54_RS08535 (EP54_08140)	alaS	1703665..1706295 (-)	2631	WP_000734064.1	alanine--tRNA ligase	-
EP54_RS08540 (EP54_08145)	recD2	1706638..1709115 (-)	2478	WP_001283311.1	ATP-dependent RecD-like DNA helicase	Machinery gene
EP54_RS08545 (EP54_08150)	-	1709117..1709785 (-)	669	WP_000567028.1	tetratricopeptide repeat protein	-
EP54_RS08550 (EP54_08155)	mnmA	1710247..1711365 (-)	1119	WP_000066097.1	tRNA 2-thiouridine(34) synthase MnmA	-
EP54_RS08555 (EP54_08160)	-	1711366..1712508 (-)	1143	WP_000409167.1	cysteine desulfurase family protein	-
EP54_RS08560 (EP54_08165)	-	1712820..1713833 (+)	1014	WP_000985886.1	LLM class flavin-dependent oxidoreductase	-

Sequence

Protein

• Length: 825 a.a.
• Molecular weight: 93048.84 Da
• Isoelectric Point: 4.4811

>NTDB_id=122311 EP54_RS08540 WP_001283311.1 1706638..1709115(-) (recD2) [Staphylococcus aureus strain M121]
MSDPTLFDYSMIKGTVEAILFQNSDNFYTVLKVDTIETNEDFDTMPTVVGFLPNIVEGDVYTFKGQVVDHPRYGKQLKAE
TFEKEMPQTKEAIISYLSSDLFKGVGKKTAQNIVNTLGDNAINDILDDHSVLEKVSGLSKKKQKQIAEQISANQESEKIM
IRLHDLGFGPKLSMAIYQFYLGDTLTILDRNPYQLIYDIKGIGFNKADQLARNIGIAYNDNERLKAALLYTLEEECIKQG
HTYLPINVVIDLTVDVLNYQDEEVIEPEKLDEMLQYLNEEKRLIIDNEQVAIPSLYYSEIKSVQNLFRIKTHTNKLTEIE
QSDLQMHIGEIEDANQVNYAASQKEALQTAINSKVMLLTGGPGTGKTTVIKGIVELYAEIHGLSLDYDDYVNDDYPVVLA
APTGRASKRLQESTGLEAMTIHRLIGWNQDTKPEDILENEINARLIIIDEMSMVDTWLFHQFLSAVPLDAQLIFVGDEDQ
LPSVGPGQVFKDLIESKAIPRVNLTEVYRQQDGSSIIELAHRMKLGQKIDITQRFHDRSFINCQANQIPTVVEKVVTSAV
NKGYTMADIQVLAPMYKGNAGIKRLNQVLQDILNPKKKDTREIEFGDVVFRKGDKVLQLVNRPNDNIFNGDIGVIVGIFW
AKENALNKDVLVVDFEGNEITFTKQDMMELTHAYCTSIHKSQGSEFPIVIMPIVKQYFRMLQRPILYTGLTRAKTSLVLL
GDPEAFDIGLKTNGQARLTQLCTLLKNYFNSEDEEMLENTATNDTGASQTTIDDQVEAPMSSNDSEEVMSDSTKTDTNVL
TEATMFKIDPMINMGEITPYDFIER

Nucleotide

• Length: 2478 bp

>NTDB_id=122311 EP54_RS08540 WP_001283311.1 1706638..1709115(-) (recD2) [Staphylococcus aureus strain M121]
ATGTCAGACCCTACACTATTTGATTATTCAATGATCAAAGGTACTGTTGAAGCGATATTGTTTCAAAACAGTGATAATTT
TTATACAGTGCTTAAAGTAGATACTATTGAAACAAATGAAGACTTTGATACAATGCCAACTGTTGTAGGGTTTCTTCCGA
ATATTGTTGAAGGCGATGTCTACACATTTAAAGGGCAAGTTGTTGATCATCCACGTTATGGTAAACAATTAAAAGCAGAG
ACTTTTGAAAAAGAAATGCCACAAACGAAAGAAGCAATTATAAGTTATTTATCTAGTGATTTGTTTAAAGGTGTAGGTAA
AAAGACAGCTCAAAATATTGTTAATACATTAGGTGACAATGCGATAAATGATATATTAGATGACCATTCAGTGCTAGAAA
AAGTTTCGGGATTATCTAAAAAGAAACAGAAACAAATTGCAGAACAAATTTCAGCAAATCAAGAATCTGAAAAAATAATG
ATTCGTTTACATGATTTAGGGTTTGGTCCTAAACTTTCAATGGCAATTTATCAGTTTTATCTCGGCGATACACTGACTAT
TTTAGATCGAAATCCATATCAATTGATTTATGATATTAAAGGTATTGGTTTTAATAAAGCAGATCAACTTGCTAGAAATA
TTGGTATCGCTTATAACGATAATGAACGATTAAAAGCTGCGTTGCTCTATACGTTAGAAGAAGAATGTATTAAACAGGGA
CATACATATTTGCCTATCAATGTTGTTATAGATTTAACGGTTGATGTATTAAATTATCAAGATGAAGAGGTCATCGAACC
TGAAAAATTAGACGAAATGTTGCAATACTTAAATGAGGAAAAACGACTAATTATTGACAATGAACAAGTTGCAATTCCAA
GTTTGTATTATTCTGAAATCAAAAGTGTTCAAAACTTATTCAGAATAAAGACGCATACAAATAAACTTACAGAAATTGAA
CAGTCAGATTTACAAATGCATATTGGTGAAATAGAAGATGCGAATCAAGTGAACTATGCAGCTTCACAAAAAGAAGCTTT
GCAAACGGCTATCAATTCTAAGGTGATGCTATTAACCGGTGGACCGGGAACAGGAAAAACGACAGTAATTAAAGGTATTG
TTGAATTATATGCTGAGATTCATGGCTTATCATTAGATTATGATGATTATGTCAATGATGATTATCCAGTTGTATTAGCA
GCGCCAACAGGAAGAGCGTCTAAGAGACTACAAGAGTCAACTGGATTAGAAGCAATGACGATTCATCGTTTAATAGGTTG
GAATCAAGACACAAAGCCAGAGGATATATTAGAAAATGAAATAAACGCACGACTCATAATCATTGATGAGATGTCTATGG
TAGATACTTGGTTGTTCCACCAATTTTTAAGTGCAGTTCCTTTAGATGCACAATTGATATTTGTAGGTGATGAGGACCAA
TTGCCTTCTGTAGGTCCTGGTCAAGTATTTAAAGATTTAATTGAATCGAAAGCTATACCACGAGTAAATCTGACTGAAGT
ATATCGTCAACAAGATGGTTCAAGCATTATAGAATTAGCACATCGAATGAAGTTGGGTCAGAAAATTGATATTACACAGC
GTTTTCATGATAGAAGTTTTATTAACTGTCAGGCAAACCAAATACCAACAGTTGTTGAGAAGGTAGTTACTAGTGCTGTT
AATAAAGGGTATACTATGGCTGATATTCAAGTGCTTGCACCAATGTATAAAGGAAATGCCGGTATTAAACGTTTAAATCA
AGTTTTACAAGATATTTTAAACCCTAAAAAGAAAGACACACGAGAAATTGAGTTTGGTGATGTAGTCTTTAGAAAAGGTG
ACAAAGTATTACAACTTGTTAATAGGCCAAATGATAACATATTCAATGGTGACATAGGAGTTATTGTTGGTATTTTTTGG
GCGAAAGAAAATGCCCTTAATAAAGATGTACTTGTTGTGGATTTTGAAGGTAATGAAATTACATTTACGAAACAAGATAT
GATGGAATTAACACATGCTTATTGTACATCAATCCATAAATCACAAGGTTCAGAATTTCCTATTGTTATCATGCCTATTG
TTAAACAGTATTTTAGAATGTTACAAAGACCGATATTATATACTGGTTTAACTAGAGCGAAAACGAGTTTAGTTTTACTT
GGTGATCCGGAAGCATTTGATATTGGATTGAAAACAAATGGTCAAGCGCGTTTAACACAATTATGTACATTGTTGAAAAA
TTATTTTAATTCAGAAGATGAAGAAATGCTGGAAAACACAGCAACTAATGATACAGGAGCTTCACAAACGACAATAGATG
ATCAAGTAGAAGCGCCAATGTCATCGAATGATAGTGAAGAAGTTATGTCTGATTCAACAAAAACAGATACAAATGTATTA
ACGGAAGCTACAATGTTTAAAATTGACCCAATGATTAATATGGGAGAAATCACGCCGTATGACTTTATAGAACGTTGA

Domains

Predicted by InterproScan.

• ATP-dependent RecD-like DNA helicase SH3 domain (SH3_13) (585-655)

• AAA domain (AAA_30) (339-544)

• UvrD-like helicase C-terminal domain (UvrD_C_2) (672-720)

• Helix-hairpin-helix containing domain (HHH_RecD2) (153-243)

3D structure

• AlphaFold DB: A0A0D6H7H2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
recD2	Bacillus subtilis subsp. subtilis str. 168	52.988	91.273	0.484