Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   DK42_RS04970 Genome accession   NZ_CP007571
Coordinates   961382..962239 (+) Length   285 a.a.
NCBI ID   WP_000163021.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain GBS2-NM     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 956382..967239
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK42_RS04940 (DK42_05055) - 956698..957579 (+) 882 WP_000919083.1 F0F1 ATP synthase subunit gamma -
  DK42_RS04945 (DK42_05060) atpD 957653..959059 (+) 1407 WP_000094375.1 F0F1 ATP synthase subunit beta -
  DK42_RS04950 (DK42_05065) - 959072..959485 (+) 414 WP_000068054.1 F0F1 ATP synthase subunit epsilon -
  DK42_RS04955 (DK42_05070) - 959550..959780 (+) 231 WP_000602601.1 DUF1146 family protein -
  DK42_RS04960 (DK42_05075) murA 959843..961114 (+) 1272 WP_000357880.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  DK42_RS04965 (DK42_05080) - 961116..961307 (+) 192 WP_000168511.1 DNA-directed RNA polymerase subunit beta -
  DK42_RS04970 (DK42_05085) endA 961382..962239 (+) 858 WP_000163021.1 DNA/RNA non-specific endonuclease Machinery gene
  DK42_RS04975 (DK42_05090) pheS 962530..963570 (+) 1041 WP_000365655.1 phenylalanine--tRNA ligase subunit alpha -
  DK42_RS04980 (DK42_05095) - 963653..964174 (+) 522 WP_000078402.1 GNAT family N-acetyltransferase -
  DK42_RS04985 (DK42_05100) pheT 964228..966633 (+) 2406 WP_000961580.1 phenylalanine--tRNA ligase subunit beta -

Sequence

Protein


Download         Length: 285 a.a.        Molecular weight: 31368.34 Da        Isoelectric Point: 10.4835

>NTDB_id=121112 DK42_RS04970 WP_000163021.1 961382..962239(+) (endA) [Streptococcus agalactiae strain GBS2-NM]
MTKKQKQITASIVTLLFSLLAIGLGESKSLPNDHILKQVTDLIISNESGKNTSLKNVSGTPSRELSESVLTSNVKKQLGT
NIAWNQSGAFIINQNKTDLNAKVSSAPYAINEIKKVNNQIVPTKANALLTKATRQYRNREETGNGRTYWKPAGWHQINGL
KGSYNHAVDRGHLIGYALVGSLRGFDASTSNPKNIATQAAWANQANSNQSTGQNYYETLVRKALDRHKTVRYRVTLIYDR
DNLLSSGSHIESKSSDGSLEFNVFIPNVQSGLLFDYATGKVKQTK

Nucleotide


Download         Length: 858 bp        

>NTDB_id=121112 DK42_RS04970 WP_000163021.1 961382..962239(+) (endA) [Streptococcus agalactiae strain GBS2-NM]
ATGACAAAAAAACAAAAACAAATAACAGCTTCGATTGTAACTTTGCTTTTTTCATTACTGGCAATAGGGTTAGGTGAAAG
TAAATCTTTGCCTAATGATCACATTTTAAAACAGGTGACAGATTTAATTATTAGTAATGAATCTGGCAAAAATACTTCCC
TTAAAAATGTATCAGGAACCCCGAGTAGAGAGTTATCTGAATCTGTTTTGACTAGCAATGTTAAAAAACAATTGGGAACA
AATATAGCTTGGAACCAGTCAGGTGCTTTTATCATTAATCAAAATAAAACAGATTTGAATGCTAAAGTGTCAAGTGCACC
ATATGCTATTAATGAAATAAAGAAGGTTAATAACCAAATTGTTCCGACTAAAGCAAATGCCTTATTAACAAAAGCAACTC
GTCAATATCGAAATCGAGAAGAAACAGGGAATGGTAGAACTTATTGGAAACCAGCTGGATGGCATCAGATAAATGGATTA
AAAGGGAGCTATAACCACGCTGTGGACAGAGGTCATTTAATTGGTTATGCTTTAGTAGGGAGTTTAAGAGGATTTGATGC
CTCCACAAGTAATCCTAAAAATATTGCCACACAAGCAGCTTGGGCAAACCAAGCTAATAGCAACCAATCAACAGGGCAAA
ATTATTATGAAACTTTAGTTCGTAAAGCATTGGATCGTCATAAAACTGTTAGGTATCGTGTGACTTTAATTTATGACAGA
GATAATCTTTTATCTTCGGGATCCCATATTGAGTCTAAATCTTCAGATGGAAGTTTAGAATTTAACGTTTTTATTCCTAA
TGTACAATCGGGATTATTATTTGATTATGCAACAGGAAAAGTGAAGCAGACAAAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(87-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

65.948

81.404

0.537
  endA Streptococcus pneumoniae D39

65.948

81.404

0.537
  endA Streptococcus pneumoniae R6

65.948

81.404

0.537
  endA Streptococcus pneumoniae TIGR4

65.948

81.404

0.537

Multiple sequence alignment