Detailed information NTG1157820

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: KJP45_RS08605
• Genome accession: NZ_OX419578
• Coordinates: 1646990..1647769 (+)
• Length: 259 a.a.
• NCBI ID: WP_003220850.1
• Uniprot ID: G4NSM6
• Organism: Bacillus subtilis isolate NRS6128
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1641990..1652769

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KJP45_RS08585 (NRS6128_08535)	trmFO	1642683..1643990 (+)	1308	WP_213414487.1	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	-
KJP45_RS08590 (NRS6128_08540)	xerC	1644058..1644972 (+)	915	WP_003231988.1	tyrosine recombinase XerC	-
KJP45_RS08595 (NRS6128_08545)	clpQ	1644985..1645530 (+)	546	WP_076457719.1	ATP-dependent protease subunit ClpQ	-
KJP45_RS08600 (NRS6128_08550)	hslU	1645538..1646950 (+)	1413	WP_256683486.1	HslU--HslV peptidase ATPase subunit	-
KJP45_RS08605 (NRS6128_08555)	codY	1646990..1647769 (+)	780	WP_003220850.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
KJP45_RS08610 (NRS6128_08560)	flgB	1648149..1648538 (+)	390	WP_003245656.1	flagellar basal body rod protein FlgB	-
KJP45_RS08615 (NRS6128_08565)	flgC	1648538..1648990 (+)	453	WP_003245521.1	flagellar basal body rod protein FlgC	-
KJP45_RS08620 (NRS6128_08570)	fliE	1649001..1649321 (+)	321	WP_003238544.1	flagellar hook-basal body complex protein FliE	-
KJP45_RS08625 (NRS6128_08575)	fliF	1649367..1650977 (+)	1611	WP_213414488.1	flagellar basal-body MS-ring/collar protein FliF	-
KJP45_RS08630 (NRS6128_08580)	fliG	1650990..1652006 (+)	1017	WP_003231981.1	flagellar motor switch protein FliG	-
KJP45_RS08635 (NRS6128_08585)	fliH	1651999..1652751 (+)	753	WP_003244804.1	flagellar assembly protein FliH	-

Sequence

Protein

• Length: 259 a.a.
• Molecular weight: 29013.22 Da
• Isoelectric Point: 4.6514

>NTDB_id=1157820 KJP45_RS08605 WP_003220850.1 1646990..1647769(+) (codY) [Bacillus subtilis isolate NRS6128]
MALLQKTRIINSMLQAAAGKPVNFKEMAETLRDVIDSNIFVVSRRGKLLGYSINQQIENDRMKKMLEDRQFPEEYTKNLF
NVPETSSNLDINSEYTAFPVENRDLFQAGLTTIVPIIGGGERLGTLILSRLQDQFNDDDLILAEYGATVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELDGNEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNNKFLIELENLKSH

Nucleotide

• Length: 780 bp

>NTDB_id=1157820 KJP45_RS08605 WP_003220850.1 1646990..1647769(+) (codY) [Bacillus subtilis isolate NRS6128]
ATGGCTTTATTACAAAAAACAAGAATTATTAACTCCATGCTGCAAGCTGCGGCAGGGAAACCGGTAAACTTCAAGGAAAT
GGCGGAGACGCTGCGGGATGTAATTGATTCCAATATTTTCGTTGTAAGCCGCAGAGGGAAACTCCTTGGGTATTCTATTA
ACCAGCAAATTGAAAATGATCGTATGAAAAAAATGCTTGAGGATCGTCAATTCCCTGAAGAGTATACGAAAAATCTGTTT
AATGTCCCTGAAACATCTTCTAACTTGGATATTAATAGTGAATATACTGCTTTCCCTGTTGAGAACAGAGACCTGTTCCA
AGCTGGTTTAACAACAATTGTGCCGATCATCGGAGGCGGGGAAAGATTAGGAACACTTATTCTTTCACGTTTACAAGATC
AATTCAATGACGATGACTTAATTCTAGCAGAATACGGCGCAACAGTTGTCGGAATGGAAATCCTAAGAGAAAAAGCAGAA
GAAATTGAAGAGGAAGCAAGAAGCAAAGCTGTCGTACAAATGGCTATCAGCTCGCTTTCTTACAGTGAGCTTGAAGCAAT
TGAGCACATTTTTGAGGAGCTTGACGGAAACGAAGGTCTTCTTGTTGCAAGTAAAATTGCTGACCGTGTCGGCATTACCC
GTTCTGTTATTGTGAACGCACTCAGAAAGCTGGAGAGCGCCGGTGTTATCGAGTCTAGATCATTAGGAATGAAAGGTACT
TATATCAAGGTACTAAACAACAAATTCCTAATTGAATTAGAAAATCTAAAATCTCATTAA

Domains

Predicted by InterproScan.

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

• CodY GAF-like domain (CodY) (3-178)

3D structure

• AlphaFold DB: G4NSM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	100	100	1
codY	Lactococcus lactis subsp. lactis strain DGCC12653	47.451	98.456	0.467