Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   SMUFR_RS06940 Genome accession   NZ_CP007016
Coordinates   1444745..1446097 (-) Length   450 a.a.
NCBI ID   WP_002262929.1    Uniprot ID   -
Organism   Streptococcus mutans UA159-FR     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1439745..1451097
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUFR_RS06930 (SMUFR_1313) rnc 1443143..1443838 (-) 696 WP_002262927.1 ribonuclease III -
  SMUFR_RS06935 (SMUFR_1314) vicX 1443945..1444748 (-) 804 WP_002262928.1 MBL fold metallo-hydrolase Regulator
  SMUFR_RS06940 (SMUFR_1315) vicK 1444745..1446097 (-) 1353 WP_002262929.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SMUFR_RS06945 (SMUFR_1316) vicR 1446090..1446797 (-) 708 WP_002262930.1 response regulator YycF Regulator
  SMUFR_RS06950 (SMUFR_1317) - 1447150..1447932 (+) 783 WP_002262931.1 amino acid ABC transporter ATP-binding protein -
  SMUFR_RS06955 (SMUFR_1318) - 1447929..1448741 (+) 813 WP_002262932.1 transporter substrate-binding domain-containing protein -
  SMUFR_RS06960 (SMUFR_1319) - 1448759..1449463 (+) 705 WP_002262933.1 amino acid ABC transporter permease -
  SMUFR_RS06965 (SMUFR_1320) - 1449478..1450128 (+) 651 WP_002262934.1 amino acid ABC transporter permease -
  SMUFR_RS06970 (SMUFR_1321) endA 1450196..1451077 (-) 882 WP_002262935.1 DNA/RNA non-specific endonuclease Machinery gene

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51697.33 Da        Isoelectric Point: 4.4637

>NTDB_id=115774 SMUFR_RS06940 WP_002262929.1 1444745..1446097(-) (vicK) [Streptococcus mutans UA159-FR]
MTNVFESSPLFLRILLAVLIILLFFYFIFLNYREYKNNNQVKQLNAKVRSLITGHYTDKLKVEDNSDLSELVNNVNDLSE
VFRLTHENLAQEKNRLTSILSYMTDGVLATDRSGKITVINDMAQKQLNVTREQALECNILDILDDDSYTYNDLITKTPEI
VLTRRDEYDEFITLRIRFALNRRESGFISGLIAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALTE
SVAPSFIKVSLDETNRMMRMITDLLSLSRIDNQTSHLDVELTNFTAFMNYILDRFDQIQSQQSTNKVYEIIRDYPDKSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKVTITMQTTDTQLILSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWANSEEGEGSTFTIVLPYENDNDAIDEWEEDEDES

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=115774 SMUFR_RS06940 WP_002262929.1 1444745..1446097(-) (vicK) [Streptococcus mutans UA159-FR]
ATGACTAATGTGTTTGAATCAAGTCCCTTATTTTTACGAATTTTATTAGCAGTTTTAATCATTTTACTCTTTTTTTATTT
TATTTTTCTCAATTACAGAGAGTATAAAAATAATAATCAAGTTAAACAGTTAAATGCTAAAGTACGTTCTTTGATTACTG
GCCATTATACTGATAAATTAAAGGTTGAGGATAACTCTGACTTGTCAGAACTAGTGAATAACGTTAATGATTTATCAGAA
GTTTTCCGTTTAACGCATGAAAATTTGGCACAGGAGAAAAACCGTCTGACTAGTATTTTATCTTATATGACAGATGGTGT
TTTGGCAACAGATCGCAGCGGAAAGATTACCGTTATTAATGATATGGCGCAAAAGCAACTGAATGTAACGCGTGAGCAGG
CATTGGAGTGCAATATTCTGGATATTTTGGATGATGATAGTTATACTTACAATGATTTGATTACAAAAACGCCAGAAATT
GTTCTGACGCGGCGTGATGAATATGATGAATTTATCACTTTACGCATTCGTTTTGCCTTAAACCGCCGTGAAAGTGGCTT
TATTTCAGGACTAATTGCTGTCTTGCATGATGCGACCGAACAGGAAAAAGAAGAACGTGAACGCCGTCTCTTTGTTTCTA
ATGTCAGTCATGAACTGCGGACACCATTAACCTCTGTAAAGTCCTATTTAGAAGCTTTGGACGATGGTGCCCTGACAGAA
TCAGTGGCTCCTAGCTTTATCAAGGTATCACTTGATGAGACTAATCGCATGATGCGTATGATTACTGATTTACTTAGCTT
ATCACGTATTGATAATCAGACCAGTCATCTAGATGTTGAATTGACGAATTTTACAGCTTTTATGAATTATATTCTGGATC
GCTTTGATCAAATTCAAAGTCAGCAATCAACTAATAAGGTTTACGAAATTATTAGAGATTATCCTGACAAATCAGTTTGG
ATTGAAATTGATACCGATAAAATGACTCAGGTAATTGATAATATTTTAAATAATGCAATCAAATATTCACCTGATGGCGG
TAAGGTGACTATAACGATGCAGACAACAGATACACAACTCATCCTTTCTATATCCGACCAAGGCTTGGGTATTCCTAAGA
AGGATCTCCCTCTTATTTTTGACCGTTTTTATCGTGTTGATAAGGCAAGAAGCCGTGCTCAAGGTGGGACTGGTTTAGGA
TTAGCAATCGCCAAAGAAATTGTCAAACAGCATAAAGGCTTTATTTGGGCCAATAGTGAGGAAGGCGAAGGGTCGACCTT
TACCATCGTTTTACCTTATGAAAACGATAATGATGCAATTGATGAATGGGAAGAAGATGAAGACGAATCATGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

PAS fold (PAS)

(96-180)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

100

100

1
  micB Streptococcus pneumoniae Cp1015

67.133

95.333

0.64

Multiple sequence alignment