Detailed information NTG1157580

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: KJP52_RS08725
• Genome accession: NZ_OX419575
• Coordinates: 1671010..1671789 (+)
• Length: 259 a.a.
• NCBI ID: WP_003220850.1
• Uniprot ID: G4NSM6
• Organism: Bacillus subtilis isolate NRS6121
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1666010..1676789

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KJP52_RS08705 (NRS6121_08640)	trmFO	1666703..1668010 (+)	1308	WP_003244725.1	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	-
KJP52_RS08710 (NRS6121_08645)	xerC	1668078..1668992 (+)	915	WP_003231988.1	tyrosine recombinase XerC	-
KJP52_RS08715 (NRS6121_08650)	clpQ	1669005..1669550 (+)	546	WP_003238555.1	ATP-dependent protease subunit ClpQ	-
KJP52_RS08720 (NRS6121_08655)	hslU	1669558..1670970 (+)	1413	WP_256683486.1	HslU--HslV peptidase ATPase subunit	-
KJP52_RS08725 (NRS6121_08660)	codY	1671010..1671789 (+)	780	WP_003220850.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
KJP52_RS08730 (NRS6121_08665)	flgB	1672169..1672558 (+)	390	WP_003245656.1	flagellar basal body rod protein FlgB	-
KJP52_RS08735 (NRS6121_08670)	flgC	1672558..1673010 (+)	453	WP_003245521.1	flagellar basal body rod protein FlgC	-
KJP52_RS08740 (NRS6121_08675)	fliE	1673021..1673341 (+)	321	WP_003238544.1	flagellar hook-basal body complex protein FliE	-
KJP52_RS08745 (NRS6121_08680)	fliF	1673387..1674997 (+)	1611	WP_010886506.1	flagellar basal-body MS-ring/collar protein FliF	-
KJP52_RS08750 (NRS6121_08685)	fliG	1675010..1676026 (+)	1017	WP_003231981.1	flagellar motor switch protein FliG	-
KJP52_RS08755 (NRS6121_08690)	fliH	1676019..1676771 (+)	753	WP_003244804.1	flagellar assembly protein FliH	-

Sequence

Protein

• Length: 259 a.a.
• Molecular weight: 29013.22 Da
• Isoelectric Point: 4.6514

>NTDB_id=1157580 KJP52_RS08725 WP_003220850.1 1671010..1671789(+) (codY) [Bacillus subtilis isolate NRS6121]
MALLQKTRIINSMLQAAAGKPVNFKEMAETLRDVIDSNIFVVSRRGKLLGYSINQQIENDRMKKMLEDRQFPEEYTKNLF
NVPETSSNLDINSEYTAFPVENRDLFQAGLTTIVPIIGGGERLGTLILSRLQDQFNDDDLILAEYGATVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELDGNEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNNKFLIELENLKSH

Nucleotide

• Length: 780 bp

>NTDB_id=1157580 KJP52_RS08725 WP_003220850.1 1671010..1671789(+) (codY) [Bacillus subtilis isolate NRS6121]
ATGGCTTTATTACAAAAAACAAGAATTATTAACTCCATGCTGCAAGCTGCGGCAGGGAAACCGGTAAACTTCAAGGAAAT
GGCGGAGACGCTGCGGGATGTAATTGATTCCAATATTTTCGTTGTAAGCCGCAGAGGGAAACTCCTTGGGTATTCAATTA
ACCAGCAAATTGAAAATGATCGTATGAAAAAAATGCTTGAGGATCGTCAATTCCCTGAAGAATATACGAAAAATCTGTTT
AATGTCCCTGAAACATCTTCTAACTTGGATATTAATAGTGAATATACTGCTTTCCCTGTTGAGAACAGAGACCTGTTTCA
AGCTGGTTTAACAACAATTGTGCCGATCATCGGAGGCGGGGAAAGATTAGGAACACTTATTCTTTCGCGTTTACAAGATC
AATTCAATGACGATGACTTAATTCTAGCTGAATACGGCGCAACAGTTGTCGGAATGGAAATCCTAAGAGAAAAAGCAGAA
GAAATTGAAGAGGAAGCAAGAAGCAAAGCTGTCGTACAAATGGCTATCAGCTCGCTTTCTTACAGTGAGCTTGAAGCAAT
TGAGCACATTTTTGAGGAGCTTGACGGAAATGAAGGTCTTCTTGTTGCAAGTAAAATTGCTGACCGTGTCGGCATTACCC
GTTCTGTTATTGTGAACGCACTCAGAAAGCTGGAGAGCGCCGGTGTTATCGAGTCTAGATCATTAGGAATGAAAGGTACT
TATATCAAGGTACTAAACAACAAATTCCTAATTGAATTAGAAAATCTAAAATCTCATTAA

Domains

Predicted by InterproScan.

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

• CodY GAF-like domain (CodY) (3-178)

3D structure

• AlphaFold DB: G4NSM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	100	100	1
codY	Lactococcus lactis subsp. lactis strain DGCC12653	47.451	98.456	0.467