Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   MMH06_RS04230 Genome accession   NZ_OV904788
Coordinates   803033..803857 (+) Length   274 a.a.
NCBI ID   WP_001036785.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain RMV7 isolate RMV7domi     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 798033..808857
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MMH06_RS04195 (IONPJBJN_00825) asnA 798123..799115 (+) 993 WP_000747993.1 aspartate--ammonia ligase -
  MMH06_RS04200 (IONPJBJN_00826) rsmD 799180..799719 (+) 540 WP_000706960.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  MMH06_RS04205 (IONPJBJN_00827) coaD 799709..800197 (+) 489 WP_001280766.1 pantetheine-phosphate adenylyltransferase -
  MMH06_RS04210 (IONPJBJN_00828) sepM 800181..801218 (+) 1038 WP_000727280.1 SepM family pheromone-processing serine protease Regulator
  MMH06_RS04215 (IONPJBJN_00829) - 801276..801506 (+) 231 WP_000615437.1 DUF1146 family protein -
  MMH06_RS04220 (IONPJBJN_00830) murA 801530..802813 (+) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  MMH06_RS04225 (IONPJBJN_00831) - 802806..802994 (+) 189 WP_001036519.1 DNA-directed RNA polymerase subunit beta -
  MMH06_RS04230 (IONPJBJN_00832) endA 803033..803857 (+) 825 WP_001036785.1 DNA-entry nuclease EndA Machinery gene
  MMH06_RS04235 (IONPJBJN_00833) - 804148..805479 (+) 1332 WP_000390039.1 hemolysin family protein -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29917.56 Da        Isoelectric Point: 10.0650

>NTDB_id=1152095 MMH06_RS04230 WP_001036785.1 803033..803857(+) (endA) [Streptococcus pneumoniae strain RMV7 isolate RMV7domi]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQAPEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSNATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=1152095 MMH06_RS04230 WP_001036785.1 803033..803857(+) (endA) [Streptococcus pneumoniae strain RMV7 isolate RMV7domi]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGGCACCTAATAGTCCCAAAACCAATCTTAGTCAGAAAAAACAAGCGCCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAATGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

98.905

100

0.989
  endA Streptococcus pneumoniae D39

98.905

100

0.989
  endA Streptococcus pneumoniae R6

98.905

100

0.989
  endA Streptococcus pneumoniae TIGR4

98.905

100

0.989

Multiple sequence alignment