Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   CKV83_RS05245 Genome accession   NZ_LT906439
Coordinates   1142449..1143297 (-) Length   282 a.a.
NCBI ID   WP_018373948.1    Uniprot ID   A0A239ST31
Organism   Streptococcus merionis strain NCTC13788     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1137449..1148297
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKV83_RS05235 (SAMEA4412692_01053) pheT 1137879..1140266 (-) 2388 WP_018373950.1 phenylalanine--tRNA ligase subunit beta -
  CKV83_RS05240 (SAMEA4412692_01054) pheS 1140677..1141723 (-) 1047 WP_018373949.1 phenylalanine--tRNA ligase subunit alpha -
  CKV83_RS05245 (SAMEA4412692_01056) endA 1142449..1143297 (-) 849 WP_018373948.1 DNA/RNA non-specific endonuclease Machinery gene
  CKV83_RS05250 (SAMEA4412692_01057) - 1143335..1143553 (-) 219 WP_018373947.1 DNA-directed RNA polymerase subunit beta -
  CKV83_RS05255 (SAMEA4412692_01058) murA 1143546..1144826 (-) 1281 WP_018373946.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  CKV83_RS05260 (SAMEA4412692_01059) - 1144916..1145146 (-) 231 WP_051071097.1 DUF1146 family protein -
  CKV83_RS05265 (SAMEA4412692_01060) - 1145321..1146199 (-) 879 WP_408640774.1 class C sortase -

Sequence

Protein


Download         Length: 282 a.a.        Molecular weight: 30456.82 Da        Isoelectric Point: 5.3468

>NTDB_id=1147133 CKV83_RS05245 WP_018373948.1 1142449..1143297(-) (endA) [Streptococcus merionis strain NCTC13788]
MKLSKKQRQSLLGGAIALILALSGYGVSESGLFGGLAGPATQDVVIPANDSTTADETPDQELASSVLVAEVRAQLPKSIE
WNGAGAFIINHNKTDLDASVSSLPYIDNKSKTVEQVKIPTVANAILEKSTRQYKNREQTGQGQTYWTPAGWHQVHDLSGE
YDHAVDRGHLIGYAIGGGLSGFDASTSNPDNIATQTAWSNQAYKPYSTGQNYYETLVRKALDKNKRVRYRVTLIYADNDD
LVAVGRQLEAKSSDGSLEFNVFVPNVQTGISIDYETGAVTVN

Nucleotide


Download         Length: 849 bp        

>NTDB_id=1147133 CKV83_RS05245 WP_018373948.1 1142449..1143297(-) (endA) [Streptococcus merionis strain NCTC13788]
ATGAAACTAAGTAAAAAACAGAGGCAGTCTCTTCTAGGAGGGGCTATAGCCCTTATTTTAGCCCTTTCGGGCTATGGTGT
CAGTGAATCGGGTCTATTTGGAGGTCTGGCTGGTCCTGCAACGCAAGATGTTGTTATTCCGGCAAATGACTCAACAACTG
CTGATGAGACGCCTGATCAGGAATTAGCAAGCTCGGTTTTAGTGGCTGAAGTGCGGGCCCAATTGCCAAAAAGCATTGAA
TGGAATGGGGCTGGTGCCTTTATCATCAATCATAATAAGACCGATCTGGATGCCAGCGTGTCTTCTTTACCCTACATTGA
TAATAAAAGCAAAACAGTCGAGCAGGTAAAAATCCCCACAGTTGCTAATGCTATTCTTGAAAAATCAACCCGTCAGTATA
AAAACCGTGAACAGACAGGTCAAGGTCAGACCTACTGGACACCAGCAGGGTGGCATCAGGTTCATGATTTGTCGGGAGAG
TACGACCATGCGGTAGATCGTGGGCATTTGATTGGTTACGCTATTGGAGGTGGCTTGTCAGGTTTTGATGCCTCAACGAG
CAATCCTGATAATATTGCCACACAGACTGCTTGGTCCAATCAAGCCTACAAGCCTTATTCGACAGGTCAGAATTACTATG
AGACGTTGGTCCGCAAGGCTCTGGATAAAAACAAGCGTGTGCGTTATCGGGTGACGCTCATCTATGCGGACAATGATGAC
CTAGTGGCAGTAGGACGCCAATTAGAGGCAAAGTCTTCTGACGGTAGTTTGGAGTTTAATGTCTTCGTTCCAAATGTTCA
AACTGGAATTAGCATTGATTACGAGACGGGAGCGGTGACTGTTAATTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(86-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A239ST31

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

69.298

80.851

0.56
  endA Streptococcus pneumoniae D39

69.298

80.851

0.56
  endA Streptococcus pneumoniae R6

69.298

80.851

0.56
  endA Streptococcus pneumoniae TIGR4

69.298

80.851

0.56

Multiple sequence alignment