Detailed information NTG1146048

Bioinformatically predicted

Overview

• Name: recD2
• Type: Machinery gene
• Locus tag: EDCC5055_RS08255
• Genome accession: NZ_LT671859
• Coordinates: 1637743..1640220 (-)
• Length: 825 a.a.
• NCBI ID: WP_001283311.1
• Uniprot ID: A0A0D6H7H2
• Organism: Staphylococcus aureus isolate Clinical isolate
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1632743..1645220

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EDCC5055_RS08230 (EDCC5055_01534)	-	1632769..1633407 (-)	639	WP_000342266.1	O-methyltransferase	-
EDCC5055_RS08235 (EDCC5055_01535)	-	1633692..1634000 (-)	309	WP_000134779.1	DUF1292 domain-containing protein	-
EDCC5055_RS08240 (EDCC5055_01536)	ruvX	1634015..1634443 (-)	429	WP_000939059.1	Holliday junction resolvase RuvX	-
EDCC5055_RS08245 (EDCC5055_01537)	-	1634447..1634707 (-)	261	WP_000426912.1	IreB family regulatory phosphoprotein	-
EDCC5055_RS08250 (EDCC5055_01538)	alaS	1634770..1637400 (-)	2631	WP_000734064.1	alanine--tRNA ligase	-
EDCC5055_RS08255 (EDCC5055_01540)	recD2	1637743..1640220 (-)	2478	WP_001283311.1	ATP-dependent RecD-like DNA helicase	Machinery gene
EDCC5055_RS08260 (EDCC5055_01541)	-	1640222..1640890 (-)	669	WP_000567028.1	tetratricopeptide repeat protein	-
EDCC5055_RS08270 (EDCC5055_01542)	mnmA	1641352..1642470 (-)	1119	WP_000066097.1	tRNA 2-thiouridine(34) synthase MnmA	-
EDCC5055_RS08275 (EDCC5055_01543)	-	1642471..1643613 (-)	1143	WP_000409167.1	cysteine desulfurase family protein	-
EDCC5055_RS08280 (EDCC5055_01544)	-	1643925..1644938 (+)	1014	WP_000985886.1	LLM class flavin-dependent oxidoreductase	-

Sequence

Protein

• Length: 825 a.a.
• Molecular weight: 93048.84 Da
• Isoelectric Point: 4.4811

>NTDB_id=1146048 EDCC5055_RS08255 WP_001283311.1 1637743..1640220(-) (recD2) [Staphylococcus aureus isolate Clinical isolate]
MSDPTLFDYSMIKGTVEAILFQNSDNFYTVLKVDTIETNEDFDTMPTVVGFLPNIVEGDVYTFKGQVVDHPRYGKQLKAE
TFEKEMPQTKEAIISYLSSDLFKGVGKKTAQNIVNTLGDNAINDILDDHSVLEKVSGLSKKKQKQIAEQISANQESEKIM
IRLHDLGFGPKLSMAIYQFYLGDTLTILDRNPYQLIYDIKGIGFNKADQLARNIGIAYNDNERLKAALLYTLEEECIKQG
HTYLPINVVIDLTVDVLNYQDEEVIEPEKLDEMLQYLNEEKRLIIDNEQVAIPSLYYSEIKSVQNLFRIKTHTNKLTEIE
QSDLQMHIGEIEDANQVNYAASQKEALQTAINSKVMLLTGGPGTGKTTVIKGIVELYAEIHGLSLDYDDYVNDDYPVVLA
APTGRASKRLQESTGLEAMTIHRLIGWNQDTKPEDILENEINARLIIIDEMSMVDTWLFHQFLSAVPLDAQLIFVGDEDQ
LPSVGPGQVFKDLIESKAIPRVNLTEVYRQQDGSSIIELAHRMKLGQKIDITQRFHDRSFINCQANQIPTVVEKVVTSAV
NKGYTMADIQVLAPMYKGNAGIKRLNQVLQDILNPKKKDTREIEFGDVVFRKGDKVLQLVNRPNDNIFNGDIGVIVGIFW
AKENALNKDVLVVDFEGNEITFTKQDMMELTHAYCTSIHKSQGSEFPIVIMPIVKQYFRMLQRPILYTGLTRAKTSLVLL
GDPEAFDIGLKTNGQARLTQLCTLLKNYFNSEDEEMLENTATNDTGASQTTIDDQVEAPMSSNDSEEVMSDSTKTDTNVL
TEATMFKIDPMINMGEITPYDFIER

Nucleotide

• Length: 2478 bp

>NTDB_id=1146048 EDCC5055_RS08255 WP_001283311.1 1637743..1640220(-) (recD2) [Staphylococcus aureus isolate Clinical isolate]
ATGTCAGACCCTACACTATTTGATTATTCAATGATCAAAGGTACTGTTGAAGCGATATTGTTTCAAAACAGTGATAATTT
TTATACAGTGCTTAAAGTAGATACTATTGAAACAAATGAAGACTTTGATACAATGCCAACTGTTGTAGGGTTTCTTCCGA
ATATTGTTGAAGGCGATGTCTACACATTTAAAGGGCAAGTTGTTGATCATCCACGTTATGGTAAACAATTAAAAGCAGAG
ACTTTTGAAAAAGAAATGCCACAAACGAAAGAAGCAATTATAAGTTATTTATCTAGTGATTTGTTTAAAGGTGTAGGTAA
AAAGACAGCTCAAAATATTGTTAATACATTAGGTGACAATGCGATAAATGATATATTAGATGACCATTCAGTGCTAGAAA
AAGTTTCGGGATTATCTAAAAAGAAACAGAAACAAATTGCAGAACAAATTTCAGCAAATCAAGAATCTGAAAAAATAATG
ATTCGTTTACATGATTTAGGGTTTGGTCCTAAACTTTCAATGGCAATTTATCAGTTTTATCTCGGCGATACACTGACTAT
TTTAGATCGAAATCCATATCAATTGATTTATGATATTAAAGGTATTGGTTTTAATAAAGCAGATCAACTTGCTAGAAATA
TTGGTATCGCTTATAACGATAATGAACGATTAAAAGCTGCGTTGCTCTATACGTTAGAAGAAGAATGTATTAAACAGGGA
CATACATATTTGCCTATCAATGTTGTTATAGATTTAACGGTTGATGTATTAAATTATCAAGATGAAGAGGTCATCGAACC
TGAAAAATTAGACGAAATGTTGCAATACTTAAATGAGGAAAAACGACTAATTATTGACAATGAACAAGTTGCAATTCCAA
GTTTGTATTATTCTGAAATCAAAAGTGTTCAAAACTTATTCAGAATAAAGACGCATACAAATAAACTTACAGAAATTGAA
CAGTCAGATTTACAAATGCATATTGGTGAAATAGAAGATGCGAATCAAGTGAACTATGCAGCTTCACAAAAAGAAGCTTT
GCAAACGGCTATCAATTCTAAGGTGATGCTATTAACCGGTGGACCGGGAACAGGAAAAACGACAGTAATTAAAGGTATTG
TTGAATTATATGCTGAGATTCATGGCTTATCATTAGATTATGATGATTATGTCAATGATGATTATCCAGTTGTATTAGCA
GCGCCAACAGGAAGAGCGTCTAAGAGACTACAAGAGTCAACTGGATTAGAAGCAATGACGATTCATCGTTTAATAGGTTG
GAATCAAGACACAAAGCCAGAGGATATATTAGAAAATGAAATAAACGCACGACTCATAATCATTGATGAGATGTCTATGG
TAGATACTTGGTTGTTCCACCAATTTTTAAGTGCAGTTCCTTTAGATGCACAATTGATATTTGTAGGTGATGAGGACCAA
TTGCCTTCTGTAGGTCCTGGTCAAGTATTTAAAGATTTAATTGAATCGAAAGCTATACCACGAGTAAATCTGACTGAAGT
ATATCGTCAACAAGATGGTTCAAGCATTATAGAATTAGCACATCGAATGAAGTTGGGTCAGAAAATTGATATTACACAGC
GTTTTCATGATAGAAGTTTTATTAACTGTCAGGCAAACCAAATACCAACAGTTGTTGAGAAGGTAGTTACTAGTGCTGTT
AATAAAGGGTATACTATGGCTGATATTCAAGTGCTTGCACCAATGTATAAAGGAAATGCCGGTATTAAACGTTTAAATCA
AGTTTTACAAGATATTTTAAACCCTAAAAAGAAAGACACACGAGAAATTGAGTTTGGTGATGTAGTCTTTAGAAAAGGTG
ACAAAGTATTACAACTTGTTAATAGGCCAAATGATAACATATTCAATGGTGACATAGGAGTTATTGTTGGTATTTTTTGG
GCGAAAGAAAATGCCCTTAATAAAGATGTACTTGTTGTGGATTTTGAAGGTAATGAAATTACATTTACGAAACAAGATAT
GATGGAATTAACACATGCTTATTGTACATCAATCCATAAATCACAAGGTTCAGAATTTCCTATTGTTATCATGCCTATTG
TTAAACAGTATTTTAGAATGTTACAAAGACCGATATTATATACTGGTTTAACTAGAGCGAAAACGAGTTTAGTTTTACTT
GGTGATCCGGAAGCATTTGATATTGGATTGAAAACAAATGGTCAAGCGCGTTTAACACAATTATGTACATTGTTGAAAAA
TTATTTTAATTCAGAAGATGAAGAAATGCTGGAAAACACAGCAACTAATGATACAGGAGCTTCACAAACGACAATAGATG
ATCAAGTAGAAGCGCCAATGTCATCGAATGATAGTGAAGAAGTTATGTCTGATTCAACAAAAACAGATACAAATGTATTA
ACGGAAGCTACAATGTTTAAAATTGACCCAATGATTAATATGGGAGAAATCACGCCGTATGACTTTATAGAACGTTGA

Domains

Predicted by InterproScan.

• ATP-dependent RecD-like DNA helicase SH3 domain (SH3_13) (585-655)

• AAA domain (AAA_30) (339-544)

• UvrD-like helicase C-terminal domain (UvrD_C_2) (672-720)

• Helix-hairpin-helix containing domain (HHH_RecD2) (153-243)

3D structure

• AlphaFold DB: A0A0D6H7H2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
recD2	Bacillus subtilis subsp. subtilis str. 168	52.988	91.273	0.484