Detailed information NTG1141168

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: DQN36_RS09125
• Genome accession: NZ_LS483425
• Coordinates: 1220522..1221388 (-)
• Length: 288 a.a.
• NCBI ID: WP_172453748.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC13737
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1215522..1226388

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN36_RS06125 (NCTC13737_01211)	-	1215715..1216101 (-)	387	WP_002990406.1	YbgA family protein	-
DQN36_RS06130 (NCTC13737_01212)	-	1216094..1216471 (-)	378	WP_023610230.1	OsmC family protein	-
DQN36_RS06135 (NCTC13737_01213)	pheT	1216581..1218986 (-)	2406	WP_111704259.1	phenylalanine--tRNA ligase subunit beta	-
DQN36_RS06140 (NCTC13737_01214)	pheS	1219196..1220239 (-)	1044	WP_063629067.1	phenylalanine--tRNA ligase subunit alpha	-
DQN36_RS09125 (NCTC13737_01216)	endA	1220522..1221388 (-)	867	WP_172453748.1	DNA/RNA non-specific endonuclease	Machinery gene
DQN36_RS06150 (NCTC13737_01217)	-	1221424..1221612 (-)	189	WP_010922120.1	DNA-directed RNA polymerase subunit beta	-
DQN36_RS06155 (NCTC13737_01218)	murA	1221616..1222887 (-)	1272	WP_002994428.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
DQN36_RS06160 (NCTC13737_01219)	-	1222952..1223176 (-)	225	WP_002985230.1	DUF1146 family protein	-
DQN36_RS06165 (NCTC13737_01220)	-	1223475..1223891 (-)	417	WP_002994425.1	F0F1 ATP synthase subunit epsilon	-
DQN36_RS06170 (NCTC13737_01221)	atpD	1223904..1225310 (-)	1407	WP_011017611.1	F0F1 ATP synthase subunit beta	-
DQN36_RS06175 (NCTC13737_01222)	-	1225472..1226347 (-)	876	WP_002985236.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 288 a.a.
• Molecular weight: 32069.43 Da
• Isoelectric Point: 10.3172

>NTDB_id=1141168 DQN36_RS09125 WP_172453748.1 1220522..1221388(-) (endA) [Streptococcus pyogenes strain NCTC13737]
MLTRKKRKRVLNSFLLILLVLGSNCLAKSDFIASNHPIKQLYQTLVGEKKKSLLTHNNLPADVPTEALAASVLTPSIKKQ
LGPDVQWNGAGAYIINRNKTDLTAKVASPPYANNETKWVQEQKVPTRANVLLTKSTRQYRNRYQTDNAYRTFKPAGWHQL
HHLKGSYDHAVDRGHLLGYALVGGLKGFDASTGNPDNIATQLSWANQANKPYSTGQNYYEGLVRRALDKGHRVRYRVTLL
YDGDNLLASGSHLEAKSSDDSLTFNVFVPNVQPGLTVDYRTGQIAINL

Nucleotide

• Length: 867 bp

>NTDB_id=1141168 DQN36_RS09125 WP_172453748.1 1220522..1221388(-) (endA) [Streptococcus pyogenes strain NCTC13737]
ATGTTAACAAGGAAAAAACGAAAAAGGGTGCTTAATTCCTTCTTATTGATTTTGTTAGTGTTGGGGTCTAACTGCCTTGC
TAAGAGTGATTTCATAGCTAGCAATCATCCTATCAAGCAACTTTATCAGACTCTTGTTGGGGAGAAGAAAAAATCATTAC
TCACACATAATAATTTGCCCGCTGATGTTCCCACAGAAGCTCTGGCGGCATCGGTATTAACACCATCAATCAAAAAGCAA
CTAGGTCCAGATGTTCAGTGGAATGGAGCAGGCGCCTATATTATCAACAGGAACAAAACAGATTTAACTGCTAAAGTAGC
CAGTCCGCCTTATGCCAACAATGAAACCAAATGGGTGCAAGAGCAAAAGGTTCCTACTAGAGCTAATGTCTTACTTACTA
AGTCGACACGACAGTATCGAAATCGCTATCAAACGGACAATGCTTATCGTACCTTTAAGCCAGCAGGTTGGCACCAATTG
CACCACTTAAAAGGAAGTTATGATCACGCGGTTGATAGAGGGCATTTGCTAGGTTATGCTTTAGTTGGTGGACTGAAAGG
TTTTGATGCTTCTACCGGTAATCCTGATAATATTGCCACTCAACTAAGTTGGGCTAATCAAGCAAATAAACCCTACTCGA
CAGGTCAGAATTACTATGAAGGTTTAGTACGTCGTGCTTTGGATAAGGGGCATCGCGTCCGCTACCGTGTCACCCTACTT
TATGATGGTGATAATCTACTAGCCAGCGGTAGCCATTTGGAGGCTAAATCCTCTGATGACAGCTTGACTTTTAACGTGTT
TGTTCCAAATGTCCAACCAGGATTGACCGTTGACTATCGGACGGGACAAATAGCTATCAATCTCTAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (120-246)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	59.494	82.292	0.49
endA	Streptococcus pneumoniae D39	59.494	82.292	0.49
endA	Streptococcus pneumoniae R6	59.494	82.292	0.49
endA	Streptococcus pneumoniae TIGR4	59.494	82.292	0.49