Detailed information NTG0114098

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: T303_RS06575
• Genome accession: NZ_CP006819
• Coordinates: 1230036..1230917 (-)
• Length: 293 a.a.
• NCBI ID: WP_011681210.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus ASCC 1275
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1225036..1235917

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
T303_RS06550 (T303_06645)	vicR	1225740..1226447 (-)	708	WP_011681206.1	response regulator YycF	Regulator
T303_RS06555 (T303_06650)	-	1226974..1227741 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
T303_RS06560 (T303_06655)	-	1227753..1228586 (+)	834	WP_011681208.1	transporter substrate-binding domain-containing protein	-
T303_RS06565 (T303_06660)	-	1228604..1229302 (+)	699	WP_011681209.1	amino acid ABC transporter permease	-
T303_RS06570 (T303_06665)	-	1229314..1229964 (+)	651	WP_024704148.1	amino acid ABC transporter permease	-
T303_RS06575 (T303_06670)	endA	1230036..1230917 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
T303_RS06580 (T303_06675)	-	1230979..1231167 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
T303_RS06585 (T303_06680)	murA	1231169..1232440 (-)	1272	WP_024704149.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
T303_RS06590 (T303_06685)	-	1232510..1232746 (-)	237	WP_002946959.1	DUF1146 family protein	-
T303_RS06595 (T303_06690)	galE	1232935..1233948 (-)	1014	WP_014621668.1	UDP-glucose 4-epimerase GalE	-
T303_RS06600 (T303_06695)	-	1233963..1234397 (-)	435	WP_231107205.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31773.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=114098 T303_RS06575 WP_011681210.1 1230036..1230917(-) (endA) [Streptococcus thermophilus ASCC 1275]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=114098 T303_RS06575 WP_011681210.1 1230036..1230917(-) (endA) [Streptococcus thermophilus ASCC 1275]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594