Detailed information NTG1139797

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: DQM45_RS06230
• Genome accession: NZ_LS483388
• Coordinates: 1250512..1251393 (-)
• Length: 293 a.a.
• NCBI ID: WP_003082810.1
• Uniprot ID: A0A4V0H9N4
• Organism: Streptococcus porcinus strain NCTC10999
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1245512..1256393

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM45_RS06210 (NCTC10999_01264)	-	1245724..1246095 (-)	372	WP_003083287.1	OsmC family protein	-
DQM45_RS06215 (NCTC10999_01265)	pheT	1246186..1248591 (-)	2406	WP_003085834.1	phenylalanine--tRNA ligase subunit beta	-
DQM45_RS06220 (NCTC10999_01266)	-	1248606..1249130 (-)	525	WP_003083083.1	N-acetyltransferase	-
DQM45_RS06225 (NCTC10999_01267)	pheS	1249176..1250219 (-)	1044	WP_039984576.1	phenylalanine--tRNA ligase subunit alpha	-
DQM45_RS06230 (NCTC10999_01268)	endA	1250512..1251393 (-)	882	WP_003082810.1	DNA/RNA non-specific endonuclease	Machinery gene
DQM45_RS06235 (NCTC10999_01269)	-	1251424..1251615 (-)	192	WP_172601601.1	DNA-directed RNA polymerase subunit beta	-
DQM45_RS06240 (NCTC10999_01270)	murA	1251615..1252886 (-)	1272	WP_003083400.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
DQM45_RS06245 (NCTC10999_01271)	-	1252961..1253185 (-)	225	WP_003085295.1	DUF1146 family protein	-
DQM45_RS06250 (NCTC10999_01272)	-	1253266..1253682 (-)	417	WP_003084986.1	F0F1 ATP synthase subunit epsilon	-
DQM45_RS06255 (NCTC10999_01273)	atpD	1253695..1255101 (-)	1407	WP_003085772.1	F0F1 ATP synthase subunit beta	-
DQM45_RS06260 (NCTC10999_01274)	-	1255219..1256097 (-)	879	WP_003084154.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 32556.77 Da
• Isoelectric Point: 10.4399

>NTDB_id=1139797 DQM45_RS06230 WP_003082810.1 1250512..1251393(-) (endA) [Streptococcus porcinus strain NCTC10999]
MSKKQPHFKKLNGILLALLITGLIAFTNGHYLASNNPLQQVLHAISGQGNNQKDSKNSTNPATPSYQLASSVLTPQVKKQ
LGQKIVWNGAGAFIVNNNKTNLKAKVSSLPYANNEVKIVESKKVPFRANALLTKSTRQYRNRNETGNGYTFWKPVGWHQI
HGLPGEYDHAVDRGHLLGYALIGGLKGYDASTSNPSNIAVQMAWANQAYLSDSTGQNYYETLIRKALDRNKRVRYRVTLL
YEKNNIISSGSHLEAKSDDGRLEFNVFVPNVQKGLRVNYQTGQVEQQSDQKAS

Nucleotide

• Length: 882 bp

>NTDB_id=1139797 DQM45_RS06230 WP_003082810.1 1250512..1251393(-) (endA) [Streptococcus porcinus strain NCTC10999]
ATGTCTAAAAAACAGCCACATTTCAAAAAGCTTAATGGAATTCTGCTAGCTCTGCTCATTACTGGGCTAATAGCCTTCAC
CAATGGCCATTACCTTGCATCCAATAACCCATTGCAGCAAGTGTTACATGCTATTTCTGGTCAAGGGAACAATCAAAAAG
ACTCTAAAAATTCGACTAATCCTGCCACACCTAGTTATCAGTTAGCTAGCTCGGTGCTTACCCCGCAAGTGAAAAAGCAA
TTAGGTCAGAAAATTGTGTGGAATGGTGCAGGTGCTTTTATCGTAAATAACAATAAAACTAATTTGAAGGCGAAAGTTTC
AAGTTTGCCTTATGCAAATAATGAAGTCAAGATAGTTGAGAGTAAGAAAGTGCCTTTTAGAGCCAACGCTTTGTTAACCA
AATCAACAAGACAATATCGTAATCGTAATGAAACTGGTAATGGTTATACCTTCTGGAAGCCAGTGGGTTGGCATCAAATC
CACGGCTTGCCAGGTGAATATGATCACGCTGTTGATAGAGGTCATTTATTGGGTTATGCCTTGATAGGTGGCTTAAAAGG
CTACGATGCTTCGACCAGCAATCCAAGCAATATTGCAGTACAAATGGCCTGGGCAAACCAGGCTTACCTCTCAGATTCAA
CAGGACAAAATTATTATGAAACTTTAATCAGAAAAGCTTTAGATAGAAATAAACGAGTTCGTTATAGAGTGACCTTACTT
TATGAAAAGAATAATATTATTTCTAGTGGTAGTCACTTAGAAGCAAAATCGGATGATGGTCGTTTGGAATTTAATGTTTT
TGTACCAAATGTTCAAAAAGGGTTAAGGGTTAATTATCAAACAGGTCAAGTTGAGCAACAAAGTGATCAAAAAGCTAGCT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (97-246)

3D structure

• AlphaFold DB: A0A4V0H9N4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	68.018	75.768	0.515
endA	Streptococcus pneumoniae D39	68.018	75.768	0.515
endA	Streptococcus pneumoniae R6	68.018	75.768	0.515
endA	Streptococcus pneumoniae TIGR4	68.018	75.768	0.515