Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   DQM69_RS06245 Genome accession   NZ_LS483381
Coordinates   1293205..1294080 (-) Length   291 a.a.
NCBI ID   WP_109982654.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain NCTC10921     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1288205..1299080
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM69_RS06230 (NCTC10921_01231) pheT 1288680..1291085 (-) 2406 WP_109982653.1 phenylalanine--tRNA ligase subunit beta -
  DQM69_RS06235 (NCTC10921_01232) - 1291214..1291735 (-) 522 WP_021673396.1 GNAT family N-acetyltransferase -
  DQM69_RS06240 (NCTC10921_01233) pheS 1291754..1292797 (-) 1044 WP_002963076.1 phenylalanine--tRNA ligase subunit alpha -
  DQM69_RS06245 (NCTC10921_01235) endA 1293205..1294080 (-) 876 WP_109982654.1 DNA/RNA non-specific endonuclease Machinery gene
  DQM69_RS06250 (NCTC10921_01236) - 1294135..1294326 (-) 192 WP_002963078.1 DNA-directed RNA polymerase subunit beta -
  DQM69_RS06255 (NCTC10921_01237) murA 1294326..1295594 (-) 1269 WP_021673393.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  DQM69_RS06260 - 1295658..1295894 (-) 237 WP_080566229.1 DUF1146 family protein -
  DQM69_RS06265 (NCTC10921_01238) - 1296247..1296666 (-) 420 WP_002963081.1 F0F1 ATP synthase subunit epsilon -
  DQM69_RS06270 (NCTC10921_01239) atpD 1296679..1298085 (-) 1407 WP_002963082.1 F0F1 ATP synthase subunit beta -

Sequence

Protein


Download         Length: 291 a.a.        Molecular weight: 32077.81 Da        Isoelectric Point: 10.1455

>NTDB_id=1139400 DQM69_RS06245 WP_109982654.1 1293205..1294080(-) (endA) [Streptococcus sobrinus strain NCTC10921]
MAKKSKRRMKQEQKVLYSLIGLVLVLLLGFVATNDKISNQNPIKHVAQQLTGQNQGRRRSSSSQEAPTQTLADSVMTQEV
KNQLPEQMDWNGAGAYILNNNKTDLDAKVASNPYVNNQTKLVQGQTVPSQANALLAKSTRQYRNRQETGNGSTDWTPAGW
HQKTNLSGAYDHAVDRGHLIAYALAGRLKGFDASTSNPANVAVQTAWANEASSSQSTGQNYYETLIRKALDKNKRVRYRV
TLVYQEDNLIASGSHLEAKSSDGSLEFNVFIPNVQKGISLDYYSGQVSPKS

Nucleotide


Download         Length: 876 bp        

>NTDB_id=1139400 DQM69_RS06245 WP_109982654.1 1293205..1294080(-) (endA) [Streptococcus sobrinus strain NCTC10921]
ATGGCTAAAAAATCAAAAAGAAGGATGAAGCAGGAGCAGAAGGTCCTCTATTCCTTAATCGGACTGGTATTGGTTCTGTT
ACTGGGCTTTGTGGCCACTAACGACAAGATTTCTAATCAGAATCCTATCAAGCATGTTGCCCAACAGTTGACTGGACAAA
ATCAAGGAAGAAGGCGCTCAAGTTCAAGCCAGGAGGCTCCAACTCAGACACTTGCTGACAGCGTCATGACCCAGGAGGTC
AAAAATCAGCTTCCGGAACAGATGGACTGGAATGGAGCAGGAGCCTACATTCTCAATAACAACAAGACCGATTTGGATGC
CAAGGTAGCCAGCAACCCCTATGTTAACAATCAAACCAAGCTGGTCCAAGGGCAGACGGTTCCTAGTCAGGCCAATGCCC
TGCTGGCTAAATCTACCCGCCAGTACCGCAATCGTCAGGAGACTGGCAATGGATCGACCGACTGGACCCCAGCTGGTTGG
CATCAAAAGACCAACCTCTCAGGAGCTTACGACCACGCAGTCGACCGGGGCCATCTGATTGCTTATGCCCTAGCTGGTAG
ACTTAAGGGCTTCGATGCCTCTACCAGCAATCCCGCCAATGTGGCGGTTCAGACCGCTTGGGCCAACGAGGCCAGCAGCT
CCCAGTCAACTGGTCAAAACTACTATGAAACCCTGATTCGTAAGGCCTTGGACAAAAACAAACGCGTCCGCTATCGGGTA
ACCTTGGTTTACCAAGAGGATAATCTGATTGCTTCTGGCAGTCATTTGGAAGCCAAGTCTTCCGACGGCAGTTTGGAATT
CAACGTCTTCATTCCCAATGTCCAAAAGGGTATCAGCCTAGATTATTATTCGGGACAGGTCTCACCCAAGTCCTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(122-249)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

66.222

77.32

0.512
  endA Streptococcus pneumoniae D39

66.222

77.32

0.512
  endA Streptococcus pneumoniae R6

66.222

77.32

0.512
  endA Streptococcus pneumoniae TIGR4

66.222

77.32

0.512

Multiple sequence alignment