Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   DQM66_RS09375 Genome accession   NZ_LS483374
Coordinates   1761866..1762690 (-) Length   274 a.a.
NCBI ID   WP_001036779.1    Uniprot ID   P0A3S3
Organism   Streptococcus pneumoniae strain NCTC7466     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1756866..1767690
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM66_RS09370 (NCTC7466_01800) - 1760306..1761637 (-) 1332 WP_000390046.1 hemolysin family protein -
  DQM66_RS09375 (NCTC7466_01801) endA 1761866..1762690 (-) 825 WP_001036779.1 DNA-entry nuclease EndA Machinery gene
  DQM66_RS09380 (NCTC7466_01802) - 1762729..1762917 (-) 189 WP_001036519.1 DNA-directed RNA polymerase subunit beta -
  DQM66_RS09385 (NCTC7466_01803) murA 1762910..1764193 (-) 1284 WP_000358027.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  DQM66_RS09390 (NCTC7466_01804) - 1764217..1764447 (-) 231 WP_000250384.1 DUF1146 family protein -
  DQM66_RS09395 (NCTC7466_01805) sepM 1764505..1765542 (-) 1038 WP_000727277.1 SepM family pheromone-processing serine protease Regulator
  DQM66_RS09400 (NCTC7466_01806) coaD 1765526..1766014 (-) 489 WP_001280727.1 pantetheine-phosphate adenylyltransferase -
  DQM66_RS09405 (NCTC7466_01807) rsmD 1766004..1766543 (-) 540 WP_000706962.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  DQM66_RS09410 (NCTC7466_01808) asnA 1766608..1767600 (-) 993 WP_000747995.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29890.57 Da        Isoelectric Point: 10.1197

>NTDB_id=1139070 DQM66_RS09375 WP_001036779.1 1761866..1762690(-) (endA) [Streptococcus pneumoniae strain NCTC7466]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=1139070 DQM66_RS09375 WP_001036779.1 1761866..1762690(-) (endA) [Streptococcus pneumoniae strain NCTC7466]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCCGTCGGCACCTAATAGTCCCAAAACCAATCTTAGTCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 3OWV

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

100

100

1
  endA Streptococcus pneumoniae D39

100

100

1
  endA Streptococcus pneumoniae R6

100

100

1
  endA Streptococcus pneumoniae TIGR4

100

100

1

Multiple sequence alignment