Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   DQM52_RS04015 Genome accession   NZ_LS483367
Coordinates   759192..760058 (+) Length   288 a.a.
NCBI ID   WP_042357882.1    Uniprot ID   A0AB38Y3D2
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC5371     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 754192..765058
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM52_RS03990 (NCTC5371_00811) atpD 755228..756634 (+) 1407 WP_111681637.1 F0F1 ATP synthase subunit beta -
  DQM52_RS03995 (NCTC5371_00812) - 756647..757063 (+) 417 WP_002985233.1 F0F1 ATP synthase subunit epsilon -
  DQM52_RS04000 (NCTC5371_00813) - 757392..757628 (+) 237 WP_274047614.1 DUF1146 family protein -
  DQM52_RS04005 (NCTC5371_00814) murA 757693..758964 (+) 1272 WP_015016870.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  DQM52_RS04010 (NCTC5371_00815) - 758968..759156 (+) 189 WP_003057490.1 DNA-directed RNA polymerase subunit beta -
  DQM52_RS04015 (NCTC5371_00816) endA 759192..760058 (+) 867 WP_042357882.1 DNA/RNA non-specific endonuclease Machinery gene
  DQM52_RS04020 (NCTC5371_00817) pheS 760341..761384 (+) 1044 WP_003057440.1 phenylalanine--tRNA ligase subunit alpha -
  DQM52_RS04025 (NCTC5371_00818) pheT 761594..763999 (+) 2406 WP_111681638.1 phenylalanine--tRNA ligase subunit beta -
  DQM52_RS04030 (NCTC5371_00819) - 764109..764486 (+) 378 WP_002993028.1 OsmC family protein -
  DQM52_RS04035 (NCTC5371_00820) - 764479..764865 (+) 387 WP_046177172.1 DUF1722 domain-containing protein -

Sequence

Protein


Download         Length: 288 a.a.        Molecular weight: 31888.90 Da        Isoelectric Point: 10.1381

>NTDB_id=1138843 DQM52_RS04015 WP_042357882.1 759192..760058(+) (endA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5371]
MLTRKKRKRVLNSFLLILLVLGSSYLAKSDFIASNHPIKQIYRTVLGDKGESSSESKEAYSEVPTEALSASVLTKSIKEQ
LGSNIEWNGAGAYIINRNKTDLNASVASLPYANNETKWVQGQKVPTRANALLTKSTRQYRNRYQTDNAYRTFKPAGWHQL
HHLKGNYDHAVDRGHLLGYALVGGLKGFDASTSNPDNIATQLSWANQADKPYSTGQNYYEGLVRRALDKGKRVRYRVTLL
YDGDNLLASGSQLEAKSADGSLAFNVFVPNVQAGLTVDYRTGQIAINP

Nucleotide


Download         Length: 867 bp        

>NTDB_id=1138843 DQM52_RS04015 WP_042357882.1 759192..760058(+) (endA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5371]
ATGTTAACAAGGAAAAAACGAAAAAGGGTGCTTAATTCCTTCTTATTGATTTTGTTAGTGTTGGGGTCTAGTTACCTTGC
TAAGAGTGATTTCATAGCTAGCAATCACCCTATTAAGCAAATTTATCGTACCGTTTTGGGAGATAAGGGTGAATCATCAT
CAGAATCAAAAGAAGCCTATAGTGAGGTTCCCACAGAAGCCCTATCCGCTTCTGTCTTGACCAAATCCATTAAGGAACAA
TTAGGTTCCAATATTGAATGGAATGGAGCAGGCGCCTATATTATCAACAGGAACAAAACAGATTTAAACGCAAGTGTAGC
CAGTCTGCCCTATGCCAATAATGAAACCAAATGGGTCCAAGGACAAAAGGTTCCTACTAGAGCTAATGCCTTACTTACTA
AGTCGACACGACAGTATCGAAATCGCTATCAAACGGACAATGCTTATCGTACCTTCAAGCCTGCTGGTTGGCACCAATTA
CATCACTTAAAAGGAAATTATGACCACGCAGTTGATAGAGGACATTTGCTAGGTTATGCTTTAGTCGGTGGACTGAAAGG
TTTTGATGCATCTACCAGTAATCCTGATAACATTGCTACTCAACTAAGTTGGGCCAATCAAGCAGATAAACCCTATTCGA
CAGGTCAAAATTACTATGAAGGATTAGTACGTCGTGCATTGGATAAGGGCAAAAGGGTCCGTTATCGTGTTACCTTGCTT
TATGATGGTGATAATCTGTTAGCCAGTGGCAGCCAGTTAGAGGCCAAATCTGCCGATGGGAGTTTAGCATTTAACGTGTT
TGTTCCAAATGTTCAAGCAGGGTTGACGGTTGATTATCGAACAGGACAGATTGCCATCAATCCCTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(121-246)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

62.393

81.25

0.507
  endA Streptococcus pneumoniae D39

62.393

81.25

0.507
  endA Streptococcus pneumoniae R6

62.393

81.25

0.507
  endA Streptococcus pneumoniae TIGR4

62.393

81.25

0.507

Multiple sequence alignment