Detailed information NTG1138674

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: DQM55_RS07815
• Genome accession: NZ_LS483364
• Coordinates: 1575799..1576659 (-)
• Length: 286 a.a.
• NCBI ID: WP_111676053.1
• Uniprot ID: A0A2X3YI35
• Organism: Streptococcus sanguinis strain NCTC11086
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1570799..1581659

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM55_RS07785 (NCTC11086_01601)	-	1570833..1571564 (-)	732	WP_002919351.1	hypothetical protein	-
DQM55_RS07790 (NCTC11086_01602)	-	1571653..1572210 (-)	558	WP_002919352.1	hypothetical protein	-
DQM55_RS07795 (NCTC11086_01603)	-	1572384..1574279 (-)	1896	WP_111676049.1	ABC-F family ATP-binding cassette domain-containing protein	-
DQM55_RS07805 (NCTC11086_01604)	-	1574532..1574897 (-)	366	WP_061602940.1	hypothetical protein	-
DQM55_RS07810 (NCTC11086_01605)	-	1574902..1575621 (-)	720	WP_111676051.1	matrixin family metalloprotease	-
DQM55_RS07815 (NCTC11086_01606)	endA	1575799..1576659 (-)	861	WP_111676053.1	DNA/RNA non-specific endonuclease	Machinery gene
DQM55_RS07820 (NCTC11086_01607)	-	1576718..1576900 (-)	183	WP_002912082.1	DNA-directed RNA polymerase subunit beta	-
DQM55_RS07825 (NCTC11086_01608)	murA	1576893..1578173 (-)	1281	WP_002912081.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
DQM55_RS07830 (NCTC11086_01609)	-	1578241..1578471 (-)	231	WP_002897901.1	DUF1146 family protein	-
DQM55_RS07835 (NCTC11086_01610)	-	1578646..1579068 (-)	423	WP_002900740.1	F0F1 ATP synthase subunit epsilon	-
DQM55_RS07840 (NCTC11086_01611)	atpD	1579076..1580482 (-)	1407	WP_002895993.1	F0F1 ATP synthase subunit beta	-
DQM55_RS07845 (NCTC11086_01612)	-	1580521..1581402 (-)	882	WP_002895995.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31244.81 Da
• Isoelectric Point: 9.8977

>NTDB_id=1138674 DQM55_RS07815 WP_111676053.1 1575799..1576659(-) (endA) [Streptococcus sanguinis strain NCTC11086]
MKRKTSQKRNSKSLQGWAGLTLALILALAGYFWGQDGQQPLQSPNSEIRVGQVQDQGTPSQELAESVLTDAVRAQLKGSI
EWNGAGAFIVNGNRTDLDAGISSKPYADNKTKFVQGQAIPTVANAFLSKSTRQYKKREETGNANTSWVPAGWHQLKNLSG
EYNHAVDRGHLLAYSLIGGLKGFDASTSNPANIAVQTAWSNQANEADSTGQNYYETKIRKALDKNKRVRYRVTLIYATET
DLVPVGSHLEAKSSDGSLEFNVFIPNVQKGIHLDYNSGRVSLDRGS

Nucleotide

• Length: 861 bp

>NTDB_id=1138674 DQM55_RS07815 WP_111676053.1 1575799..1576659(-) (endA) [Streptococcus sanguinis strain NCTC11086]
ATGAAAAGAAAGACTAGTCAGAAAAGGAATTCTAAGAGCCTGCAAGGCTGGGCTGGGCTGACTCTGGCTTTGATTTTAGC
TCTGGCTGGCTATTTCTGGGGACAGGACGGTCAGCAGCCACTTCAGAGTCCAAATTCAGAAATCAGAGTTGGGCAAGTCC
AAGATCAGGGCACCCCTAGTCAGGAACTGGCTGAGAGCGTTCTGACGGATGCTGTCCGAGCTCAGCTTAAAGGCAGCATT
GAATGGAATGGAGCTGGCGCCTTTATCGTGAATGGGAATAGGACAGACTTGGATGCGGGGATTTCTAGCAAACCCTACGC
TGACAATAAGACCAAGTTTGTACAAGGGCAAGCTATTCCGACGGTGGCGAATGCCTTTTTATCCAAGTCTACCCGCCAGT
ACAAAAAACGGGAAGAAACTGGAAATGCCAACACTTCATGGGTACCGGCAGGCTGGCATCAACTCAAGAACCTCTCTGGT
GAGTACAATCATGCTGTGGACCGCGGACATCTCTTGGCCTATTCACTGATTGGTGGTTTGAAGGGCTTTGATGCCTCCAC
CAGCAATCCTGCCAATATCGCTGTGCAGACGGCCTGGTCCAACCAAGCCAATGAGGCGGATTCGACAGGGCAGAATTACT
ATGAGACAAAGATCCGTAAGGCTTTGGATAAGAACAAGCGGGTGCGCTACCGGGTAACCTTGATTTATGCCACGGAGACG
GATTTAGTACCGGTTGGGTCACATTTAGAGGCCAAGTCCAGCGATGGTAGTCTGGAATTCAATGTCTTTATCCCGAATGT
GCAAAAAGGGATTCACCTGGACTATAATAGTGGCAGGGTCAGTCTGGATAGAGGTTCTTAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (103-256)

3D structure

• AlphaFold DB: A0A2X3YI35

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	74.107	78.322	0.58
endA	Streptococcus pneumoniae D39	74.107	78.322	0.58
endA	Streptococcus pneumoniae R6	74.107	78.322	0.58
endA	Streptococcus pneumoniae TIGR4	74.107	78.322	0.58