Detailed information NTG1136938

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: DQL10_RS09300
• Genome accession: NZ_LS483331
• Coordinates: 607343..608209 (+)
• Length: 288 a.a.
• NCBI ID: WP_023612376.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12057
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 602343..613209

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL10_RS03145 (NCTC12057_00617)	-	602384..603259 (+)	876	WP_002985236.1	F0F1 ATP synthase subunit gamma	-
DQL10_RS03150 (NCTC12057_00618)	atpD	603421..604827 (+)	1407	WP_002985235.1	F0F1 ATP synthase subunit beta	-
DQL10_RS03155 (NCTC12057_00619)	-	604840..605256 (+)	417	WP_002985233.1	F0F1 ATP synthase subunit epsilon	-
DQL10_RS03160 (NCTC12057_00620)	-	605555..605779 (+)	225	WP_002985230.1	DUF1146 family protein	-
DQL10_RS03165 (NCTC12057_00621)	murA	605844..607115 (+)	1272	WP_002990414.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
DQL10_RS03170 (NCTC12057_00622)	-	607119..607307 (+)	189	WP_011017613.1	DNA-directed RNA polymerase subunit beta	-
DQL10_RS09300 (NCTC12057_00623)	endA	607343..608209 (+)	867	WP_023612376.1	DNA/RNA non-specific endonuclease	Machinery gene
DQL10_RS03180 (NCTC12057_00625)	pheS	608492..609535 (+)	1044	WP_003057440.1	phenylalanine--tRNA ligase subunit alpha	-
DQL10_RS03185 (NCTC12057_00626)	pheT	609745..612150 (+)	2406	WP_032465590.1	phenylalanine--tRNA ligase subunit beta	-
DQL10_RS03190 (NCTC12057_00627)	-	612260..612637 (+)	378	WP_002993028.1	OsmC family protein	-
DQL10_RS03195 (NCTC12057_00628)	-	612630..613016 (+)	387	WP_002990406.1	YbgA family protein	-

Sequence

Protein

• Length: 288 a.a.
• Molecular weight: 32087.59 Da
• Isoelectric Point: 10.5080

>NTDB_id=1136938 DQL10_RS09300 WP_023612376.1 607343..608209(+) (endA) [Streptococcus pyogenes strain NCTC12057]
MLAKKKRKRVLNSFLLILLVLGSNCLAKSDFIASNHPIKQLYQTLVGEKKKSLLTHNNLPADVPTEALAASVLTPSIKKQ
LGPDVQWNGAGAYIINRNKTDLNAKVASLPYANNETKWVQEQKVPKRANALLTKSTRQYRNRYQTDNAYRNFKPAGWHRL
HHLKGSYDHAVDRGHLLGYALVGGLKGLDASTGNPDNIATQLSWANQANKPYSTGQNYYEGLVRRALDKGHRVRYRVTLL
YDGDNLLASGSHLEAKSSDGSLTFNVFVPNVQPGLTVDYRTRQIAINL

Nucleotide

• Length: 867 bp

>NTDB_id=1136938 DQL10_RS09300 WP_023612376.1 607343..608209(+) (endA) [Streptococcus pyogenes strain NCTC12057]
ATGTTAGCAAAGAAAAAACGAAAAAGGGTGCTTAATTCCTTCTTATTGATTTTGTTAGTGTTGGGGTCTAACTGCCTTGC
TAAGAGTGATTTCATAGCTAGCAATCACCCTATCAAGCAACTTTATCAGACTCTTGTTGGGGAGAAGAAAAAATCATTAC
TCACACATAATAATTTGCCCGCTGATGTTCCCACAGAAGCTCTGGCGGCATCGGTATTAACACCATCAATCAAAAAGCAA
CTAGGTCCAGATGTTCAGTGGAATGGAGCAGGCGCCTATATTATCAACAGGAACAAAACAGATTTAAATGCTAAGGTAGC
CAGTCTGCCCTATGCCAACAATGAAACCAAATGGGTGCAAGAGCAAAAGGTTCCTAAAAGAGCTAATGCCTTACTTACTA
AGTCGACACGACAGTATCGAAATCGCTATCAAACGGACAATGCTTATCGTAACTTTAAGCCAGCAGGTTGGCACCGATTG
CACCACTTAAAAGGAAGTTATGATCACGCGGTTGATAGAGGGCATTTGCTAGGTTATGCTTTAGTTGGTGGACTGAAAGG
TTTAGATGCTTCTACCGGTAATCCTGATAATATTGCCACTCAACTAAGTTGGGCTAATCAAGCAAATAAACCCTACTCGA
CAGGTCAGAATTACTATGAAGGTTTAGTACGTCGTGCTTTAGATAAGGGGCATCGCGTCCGCTACCGTGTCACCCTACTT
TATGATGGTGATAATCTACTAGCCAGTGGTAGCCATTTGGAGGCTAAATCCTCTGATGGCAGCTTGACTTTTAACGTGTT
TGTTCCAAATGTCCAACCAGGATTGACCGTTGATTATAGGACGAGACAAATAGCTATCAATCTCTAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (111-246)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	58.65	82.292	0.483
endA	Streptococcus pneumoniae D39	58.65	82.292	0.483
endA	Streptococcus pneumoniae R6	58.65	82.292	0.483
endA	Streptococcus pneumoniae TIGR4	58.65	82.292	0.483