Detailed information NTG1136864

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: DQL25_RS06510
• Genome accession: NZ_LS483330
• Coordinates: 1259620..1260486 (-)
• Length: 288 a.a.
• NCBI ID: WP_111703380.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8328
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1254620..1265486

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL25_RS06490 (NCTC8328_01303)	-	1254813..1255199 (-)	387	WP_002990406.1	YbgA family protein	-
DQL25_RS06495 (NCTC8328_01304)	-	1255192..1255569 (-)	378	WP_111703377.1	OsmC family protein	-
DQL25_RS06500 (NCTC8328_01305)	pheT	1255679..1258084 (-)	2406	WP_111703379.1	phenylalanine--tRNA ligase subunit beta	-
DQL25_RS06505 (NCTC8328_01306)	pheS	1258294..1259337 (-)	1044	WP_003057440.1	phenylalanine--tRNA ligase subunit alpha	-
DQL25_RS06510 (NCTC8328_01308)	endA	1259620..1260486 (-)	867	WP_111703380.1	DNA/RNA non-specific endonuclease	Machinery gene
DQL25_RS06515 (NCTC8328_01309)	-	1260522..1260710 (-)	189	WP_011017613.1	DNA-directed RNA polymerase subunit beta	-
DQL25_RS06520 (NCTC8328_01310)	murA	1260714..1261985 (-)	1272	WP_002994428.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
DQL25_RS06525 (NCTC8328_01311)	-	1262050..1262286 (-)	237	WP_281726905.1	DUF1146 family protein	-
DQL25_RS06530 (NCTC8328_01312)	-	1262573..1262989 (-)	417	WP_002985233.1	F0F1 ATP synthase subunit epsilon	-
DQL25_RS06535 (NCTC8328_01313)	atpD	1263002..1264408 (-)	1407	WP_011017611.1	F0F1 ATP synthase subunit beta	-
DQL25_RS06540 (NCTC8328_01314)	-	1264570..1265445 (-)	876	WP_002985236.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 288 a.a.
• Molecular weight: 32039.45 Da
• Isoelectric Point: 10.4166

>NTDB_id=1136864 DQL25_RS06510 WP_111703380.1 1259620..1260486(-) (endA) [Streptococcus pyogenes strain NCTC8328]
MLAKKKRKRVLNSFLLILLVLGSNCLAKSDFIASNHPIKQLYQTLVGEKKKSLLTHNNLPADVPTEALAASVLTPSIKKQ
LGPDVQWNGVGAYIINRNKTNLTAKVASPPYANNETKWVQEQKVPTRANALLTKSTRQYRNRYQTNNAYRTFKPAGWHRL
HHLKGSYDHAVDRGHLLGYALVGGLKGFDASTGNPDNIATQLSWANQANKPYSTGQNYYEGLVRRALDKGHRVRYRVTLL
YDDDNLLASGSHLEAKSSDDSLAFNVFVPNVQAGLTVDYRTGQIAINL

Nucleotide

• Length: 867 bp

>NTDB_id=1136864 DQL25_RS06510 WP_111703380.1 1259620..1260486(-) (endA) [Streptococcus pyogenes strain NCTC8328]
ATGTTAGCAAAGAAAAAACGAAAAAGGGTGCTTAATTCCTTCTTATTGATTTTGTTAGTGTTGGGGTCTAACTGCCTTGC
TAAGAGTGATTTCATAGCTAGCAATCACCCTATCAAGCAACTTTATCAGACTCTTGTTGGGGAGAAGAAAAAATCATTAC
TCACACATAATAATTTGCCCGCCGATGTTCCCACAGAAGCTCTGGCGGCATCGGTATTAACACCATCAATCAAAAAGCAA
CTAGGTCCAGATGTTCAGTGGAATGGAGTAGGCGCCTATATTATCAACAGGAACAAAACAAATTTAACTGCTAAGGTAGC
CAGTCCGCCTTATGCCAACAATGAAACCAAATGGGTGCAAGAGCAAAAGGTTCCTACTAGAGCTAATGCCTTACTTACTA
AGTCGACACGACAGTATCGAAATCGCTATCAAACGAACAATGCTTATCGTACCTTTAAGCCAGCAGGTTGGCACCGATTG
CACCACTTAAAAGGAAGTTATGATCACGCGGTTGATAGAGGGCATTTGCTAGGTTATGCTTTAGTTGGTGGACTGAAAGG
TTTTGATGCTTCTACTGGTAATCCTGATAATATTGCCACTCAACTAAGTTGGGCTAATCAAGCAAATAAACCCTACTCGA
CAGGTCAGAATTACTATGAAGGTTTAGTACGTCGTGCTTTGGATAAGGGGCATCGCGTCCGCTACCGTGTCACCCTACTT
TATGATGATGATAATCTACTAGCCAGCGGTAGCCATTTGGAGGCTAAATCCTCTGATGACAGCTTGGCTTTTAACGTGTT
TGTTCCAAATGTCCAAGCAGGATTGACCGTTGACTATCGGACGGGACAAATAGCTATCAATCTCTAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (106-246)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	59.916	82.292	0.493
endA	Streptococcus pneumoniae D39	59.916	82.292	0.493
endA	Streptococcus pneumoniae R6	59.916	82.292	0.493
endA	Streptococcus pneumoniae TIGR4	59.916	82.292	0.493