Detailed information    

experimental Experimentally validated

Overview

Name   recC   Type   Machinery gene
Locus tag   OK783_RS06970 Genome accession   NZ_CP115654
Coordinates   1330427..1333633 (-) Length   1068 a.a.
NCBI ID   WP_010951252.1    Uniprot ID   Q5F720
Organism   Neisseria gonorrhoeae strain FA1090     
Function   homologous recombination   
Homologous recombination

Function

Mutations in the Gc recB, recC or recD genes revealed that a Gc RecBCD pathway also exists and is involved in DNA transformation and DNA repair but not in pilin antigenic variation.


Genomic Context

Location: 1325427..1338633
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OK783_RS06950 (OK783_06950) mtrC 1326033..1327271 (-) 1239 WP_003697358.1 multidrug efflux RND transporter periplasmic adaptor subunit MtrC -
  OK783_RS06955 (OK783_06955) mtrR 1327522..1328154 (+) 633 WP_003693763.1 multidrug efflux system transcriptional repressor MtrR -
  OK783_RS06960 (OK783_06960) - 1328247..1328459 (-) 213 WP_050161448.1 hypothetical protein -
  OK783_RS06965 (OK783_06965) mtrF 1328791..1330359 (+) 1569 WP_010951251.1 AbgT family antimetabolite efflux transporter MtrF -
  OK783_RS06970 (OK783_06970) recC 1330427..1333633 (-) 3207 WP_010951252.1 exodeoxyribonuclease V subunit gamma Machinery gene
  OK783_RS06975 (OK783_06975) - 1333734..1335143 (-) 1410 WP_003702955.1 PepSY-associated TM helix domain-containing protein -
  OK783_RS06980 (OK783_06980) ccoP 1335487..1336806 (-) 1320 WP_003695664.1 cytochrome-c oxidase, cbb3-type subunit III -
  OK783_RS06985 (OK783_06985) - 1336830..1337000 (-) 171 WP_003693747.1 CcoQ/FixQ family Cbb3-type cytochrome c oxidase assembly chaperone -
  OK783_RS06990 (OK783_06990) ccoO 1337005..1337616 (-) 612 WP_002212596.1 cytochrome-c oxidase, cbb3-type subunit II -

Sequence

Protein


Download         Length: 1068 a.a.        Molecular weight: 120004.47 Da        Isoelectric Point: 4.7847

>NTDB_id=1133 OK783_RS06970 WP_010951252.1 1330427..1333633(-) (recC) [Neisseria gonorrhoeae strain FA1090]
MFYLYQSNRLESLAALFARIQKVKPLKCALQPEQIVVQSQGMRRYLNTCLARDLGVAANLAFSLPAGLTWKLMKKLIPGI
PELSPFAPEVMRWRLLDLFRSAEFQNGAEFEDVRNVLQDYLGSGESADYQLAGQLADIFDQYLVYRPQWIDAWQQGRILG
LGDDEIWQSKLWRYLDDGRQSAPHRVALWEKLLAALDKDKLPERYFVFGISTMAPMYLQLLHKLSEHCDVFVFALNPSGM
HWGNVIEAAQILKGGGDPDLTQAGHPLLASLGKQGRDFFDFLNEMEIEEETPVFEEGGRDTLLHALQTDIQNLKMPSENV
GSVGTDDGSICIVSAHSPLRELQILKDKLLKILHEHPDWQPHDIAVLTPNIEPYTPFIEAVFGQAQPGAQALPYSVSDVK
ISRRQPFFYALECVSDLLESRFEVGKVLALLETAPVLRRFGLTGDDLPLLHDMVADLNVHWGLDGEMRGGTDQLFTWKQA
ADRMILGWMLPEGGNPMWQDVSAWYADVNQTAMFGRFAAFLETLSDIARIWRQPATVGEWVARCRDLLETLFQAGPDDQK
AVQNLENEWVKWQEESTLAGFFGQLPQQTVIRHIRRFLDSESEAGFLRGGITFCSMVPMRSLPFKVICLLGLNDGDFPRN
TKAAVFDLVAKHPAKGDRARRDDDRYLFLEALISAREILYLSYIGRDIRKDEELASSSLLGELIDTVAAMTGTNSRQLAQ
NWIEQHPLQAFSRRYFQEGGRSDGIFGTRTDYAAALGQTPEPPQPFFDQPVENAEPVAEIGQDEFIRFWRNPVKVWLQQL
AWSEPHIGEAWEPAEPFEPQHAEQIAETYIGARREGQDFSQTAARIAAESLLPSGELGKLWQQSFQTAAKQIDTAVLNSP
KLPPFPYAIPSDGQILKGSLGNLYRCGQVFYAYGKPNAPQRVAFLLEHLIFCAVMPSEAETRQTFIVQSGETEVLAEIAQ
DRALQLLSEWMAFFNIGQNRPLPFFAKTSLAAAEAFAQKQDWEAALKKAQTAYYGSKVSKGQKDYTEVALVFGNASQNPL
EQPLFENLARLLADTLAAAEKREGTGAA

Nucleotide


Download         Length: 3207 bp        

>NTDB_id=1133 OK783_RS06970 WP_010951252.1 1330427..1333633(-) (recC) [Neisseria gonorrhoeae strain FA1090]
ATGTTTTACCTGTACCAATCCAACCGCCTCGAATCGCTCGCTGCACTGTTTGCCCGCATTCAAAAAGTCAAACCGCTGAA
ATGTGCCTTGCAGCCCGAACAGATTGTTGTGCAGAGCCAGGGGATGCGCCGCTACCTCAACACCTGCCTCGCCCGCGATT
TGGGCGTGGCGGCGAATTTGGCGTTCAGCCTGCCCGCCGGCCTGACGTGGAAGTTGATGAAAAAACTGATTCCCGGTATT
CCGGAACTCAGCCCGTTTGCACCCGAAGTCATGCGCTGGCGGCTGCTGGATTTGTTCCGCAGCGCAGAATTTCAAAACGG
AGCGGAATTTGAAGATGTGAGGAATGTGCTGCAAGACTATCTGGGCAGCGGAGAATCGGCGGATTACCAGCTTGCGGGAC
AGCTTGCAGACATATTCGACCAATACCTCGTGTACCGTCCTCAGTGGATAGACGCTTGGCAGCAGGGCAGGATACTCGGT
TTGGGCGACGACGAAATCTGGCAGTCCAAACTGTGGCGTTACCTCGACGACGGCAGGCAGAGCGCGCCGCACCGTGTCGC
GTTGTGGGAAAAACTGCTTGCCGCGTTGGACAAGGATAAGCTGCCCGAGCGTTATTTCGTGTTCGGCATTTCCACGATGG
CGCCGATGTATTTGCAGCTTTTGCACAAGCTGTCCGAACATTGCGACGTGTTCGTGTTCGCACTTAATCCGAGCGGGATG
CATTGGGGCAACGTCATCGAAGCGGCGCAAATCCTCAAAGGCGGCGGCGATCCCGATCTGACGCAGGCAGGGCATCCGCT
GCTTGCCTCATTGGGCAAGCAGGGGCGCGACTTTTTCGACTTTTTGAACGAAATGGAAATAGAAGAAGAAACGCCGGTAT
TTGAAGAAGGCGGGCGCGATACGCTTTTGCACGCCCTGCAAACCGATATTCAAAACCTGAAAATGCCGTCTGAAAATGTG
GGAAGCGTCGGTACGGATGACGGCTCGATATGCATCGTATCCGCACACAGCCCCTTGCGCGAATTGCAGATACTCAAAGA
CAAACTGTTGAAAATTCTGCATGAACATCCCGATTGGCAGCCGCATGATATCGCCGTATTAACCCCGAATATCGAACCCT
ATACGCCTTTTATCGAAGCCGTGTTCGGACAGGCGCAACCCGGCGCGCAGGCATTGCCGTATTCCGTTTCGGACGTGAAA
ATCAGCCGCCGGCAACCGTTTTTTTATGCGTTGGAGTGCGTGTCCGACTTGCTGGAAAGCCGTTTTGAAGTCGGCAAAGT
GCTCGCGCTTTTGGAAACCGCGCCCGTGTTGCGCCGTTTCGGACTGACCGGGGACGATTTGCCGCTTTTGCACGATATGG
TTGCCGATTTGAACGTCCATTGGGGATTGGACGGAGAAATGCGCGGCGGCACGGATCAGCTGTTTACCTGGAAGCAGGCG
GCAGACCGTATGATATTGGGCTGGATGCTGCCCGAAGGCGGCAACCCGATGTGGCAGGATGTCAGCGCGTGGTATGCCGA
CGTGAATCAAACCGCCATGTTCGGACGTTTTGCCGCCTTCCTCGAAACCCTGTCGGATATTGCCCGGATATGGCGGCAAC
CTGCGACGGTCGGCGAATGGGTGGCGCGTTGCCGGGATTTGCTTGAAACATTGTTTCAAGCCGGGCCCGATGACCAAAAG
GCAGTCCAAAACCTCGAAAACGAATGGGTCAAATGGCAGGAAGAGAGCACTTTGGCTGGGTTTTTCGGACAGTTGCCGCA
ACAAACCGTCATCCGCCATATCCGCCGCTTCCTCGACAGCGAAAGCGAGGCAGGCTTTTTACGCGGCGGCATCACCTTTT
GCAGTATGGTGCCGATGCGCAGCCTGCCCTTTAAAGTCATCTGCCTGTTGGGTTTGAACGACGGAGATTTTCCCCGCAAT
ACCAAAGCCGCCGTATTCGACCTGGTTGCCAAACATCCCGCCAAAGGCGACCGCGCCCGCCGCGACGACGACCGCTACCT
CTTCCTCGAAGCCCTCATCAGCGCGCGCGAAATCCTGTATTTGTCCTACATCGGGCGCGACATCCGCAAAGACGAAGAAC
TGGCTTCGTCTTCCCTGTTGGGCGAACTCATCGATACCGTTGCCGCCATGACCGGCACAAACAGCCGCCAACTTGCACAA
AATTGGATAGAACAGCATCCGCTGCAAGCCTTCTCGCGCCGATATTTCCAAGAAGGCGGACGTTCAGACGGCATATTCGG
CACGCGTACCGACTACGCCGCCGCGCTCGGACAAACGCCCGAACCGCCGCAACCCTTTTTCGACCAACCCGTAGAAAACG
CCGAACCTGTTGCCGAAATCGGACAGGACGAATTTATCCGCTTCTGGCGCAACCCCGTCAAAGTATGGCTGCAGCAGCTT
GCGTGGAGCGAACCCCATATCGGCGAAGCCTGGGAGCCTGCCGAACCCTTCGAGCCGCAACACGCGGAGCAAATCGCCGA
AACCTATATCGGGGCGCGCCGCGAAGGACAAGATTTTTCCCAAACCGCCGCCCGTATCGCGGCGGAAAGCCTGCTGCCTT
CCGGAGAATTGGGAAAACTTTGGCAGCAGTCCTTCCAAACCGCCGCCAAACAAATCGACACGGCGGTTTTAAACAGCCCC
AAACTGCCCCCGTTTCCATACGCCATACCGTCGGACGGGCAAATCCTGAAAGGCAGCTTGGGCAATCTGTACCGCTGCGG
TCAGGTGTTTTACGCCTACGGCAAACCCAATGCGCCGCAACGTGTGGCTTTTTTGTTGGAACACCTGATATTTTGCGCCG
TTATGCCGTCTGAAGCCGAAACGCGGCAAACCTTTATCGTCCAATCCGGAGAAACAGAAGTATTGGCGGAAATCGCGCAA
GACAGGGCATTGCAGCTGTTGTCGGAATGGATGGCGTTTTTCAATATCGGGCAAAACCGCCCGCTGCCGTTTTTTGCCAA
AACCTCGCTTGCCGCCGCCGAAGCGTTTGCCCAAAAACAAGATTGGGAAGCCGCCCTGAAAAAAGCCCAAACCGCCTATT
ACGGCAGCAAAGTCAGCAAAGGGCAGAAAGACTATACCGAAGTCGCCCTCGTGTTCGGCAACGCAAGCCAAAACCCGCTC
GAACAGCCCCTGTTTGAAAACCTCGCCCGCCTGCTCGCCGACACGCTTGCCGCAGCGGAAAAGAGGGAAGGGACCGGAGC
AGCATAA

Domains

Predicted by InterproScan.

Exodeoxyribonuclease V, gamma subunit (Exonuc_V_gamma)

(2-312)

RecC C-terminal domain (RecC_C)

(778-996)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5F720

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value

References

[1] I J Mehr et al. (1998) Differential roles of homologous recombination pathways in Neisseria gonorrhoeae pilin antigenic variation, DNA transformation and DNA repair. Molecular Microbiology 30(4):697-710. [PMID: 10094619]