Detailed information NTG1132124

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: H1W86_RS05285
• Genome accession: NZ_LR822042
• Coordinates: 1007505..1008386 (-)
• Length: 293 a.a.
• NCBI ID: WP_011681210.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1358
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1002505..1013386

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W86_RS05260 (STHERMO_1144)	vicR	1003209..1003916 (-)	708	WP_011681206.1	response regulator YycF	Regulator
H1W86_RS05265 (STHERMO_1145)	-	1004443..1005210 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
H1W86_RS05270 (STHERMO_1146)	-	1005222..1006055 (+)	834	WP_014608373.1	transporter substrate-binding domain-containing protein	-
H1W86_RS05275 (STHERMO_1147)	-	1006073..1006771 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
H1W86_RS05280 (STHERMO_1148)	-	1006783..1007433 (+)	651	WP_014608375.1	amino acid ABC transporter permease	-
H1W86_RS05285 (STHERMO_1149)	endA	1007505..1008386 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
H1W86_RS05290 (STHERMO_1150)	-	1008448..1008636 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
H1W86_RS05295 (STHERMO_1151)	murA	1008638..1009909 (-)	1272	WP_014608377.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
H1W86_RS05300 (STHERMO_1152)	-	1009979..1010215 (-)	237	WP_002946959.1	DUF1146 family protein	-
H1W86_RS05305 (STHERMO_1154)	galE	1010403..1011416 (-)	1014	WP_011681212.1	UDP-glucose 4-epimerase GalE	-
H1W86_RS05310 (STHERMO_1155)	-	1011431..1011886 (-)	456	WP_024009932.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31773.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=1132124 H1W86_RS05285 WP_011681210.1 1007505..1008386(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_1358]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=1132124 H1W86_RS05285 WP_011681210.1 1007505..1008386(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_1358]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTAGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594