Detailed information NTG1131944

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: H1W92_RS05510
• Genome accession: NZ_LR822039
• Coordinates: 1031728..1032609 (-)
• Length: 293 a.a.
• NCBI ID: WP_011226089.1
• Uniprot ID: Q5M441
• Organism: Streptococcus thermophilus isolate STH_CIRM_1116
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1026728..1037609

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W92_RS05485 (STHERMO_1195)	vicR	1027428..1028135 (-)	708	WP_011227274.1	response regulator YycF	Regulator
H1W92_RS05490 (STHERMO_1197)	-	1028667..1029434 (+)	768	WP_011227275.1	amino acid ABC transporter ATP-binding protein	-
H1W92_RS05495 (STHERMO_1198)	-	1029446..1030279 (+)	834	WP_011227276.1	transporter substrate-binding domain-containing protein	-
H1W92_RS05500 (STHERMO_1199)	-	1030297..1030995 (+)	699	WP_011226087.1	amino acid ABC transporter permease	-
H1W92_RS05505 (STHERMO_1200)	-	1031007..1031657 (+)	651	WP_180475730.1	amino acid ABC transporter permease	-
H1W92_RS05510 (STHERMO_1201)	endA	1031728..1032609 (-)	882	WP_011226089.1	DNA/RNA non-specific endonuclease	Machinery gene
H1W92_RS05515 (STHERMO_1202)	-	1032671..1032859 (-)	189	WP_011227277.1	DNA-directed RNA polymerase subunit beta	-
H1W92_RS05520 (STHERMO_1203)	murA	1032861..1034132 (-)	1272	WP_041827046.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
H1W92_RS05525 (STHERMO_1204)	-	1034202..1034438 (-)	237	WP_002946959.1	DUF1146 family protein	-
H1W92_RS05530 (STHERMO_1205)	galE	1034626..1035639 (-)	1014	WP_011227279.1	UDP-glucose 4-epimerase GalE	-
H1W92_RS05535 (STHERMO_1206)	-	1035654..1036109 (-)	456	WP_041827047.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31757.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=1131944 H1W92_RS05510 WP_011226089.1 1031728..1032609(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_1116]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVAGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=1131944 H1W92_RS05510 WP_011226089.1 1031728..1032609(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_1116]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTGCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCCCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

3D structure

• AlphaFold DB: Q5M441

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594