Detailed information NTG1131829

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: H1W84_RS05430
• Genome accession: NZ_LR822036
• Coordinates: 1024102..1024983 (-)
• Length: 293 a.a.
• NCBI ID: WP_014608376.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1055
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1019102..1029983

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W84_RS05405 (STHERMO_1191)	vicR	1019806..1020513 (-)	708	WP_011681206.1	response regulator YycF	Regulator
H1W84_RS05410 (STHERMO_1192)	-	1021040..1021807 (+)	768	WP_014608372.1	amino acid ABC transporter ATP-binding protein	-
H1W84_RS05415 (STHERMO_1193)	-	1021819..1022652 (+)	834	WP_014608373.1	transporter substrate-binding domain-containing protein	-
H1W84_RS05420 (STHERMO_1194)	-	1022670..1023368 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
H1W84_RS05425 (STHERMO_1195)	-	1023380..1024030 (+)	651	WP_014608375.1	amino acid ABC transporter permease	-
H1W84_RS05430 (STHERMO_1196)	endA	1024102..1024983 (-)	882	WP_014608376.1	DNA/RNA non-specific endonuclease	Machinery gene
H1W84_RS05435 (STHERMO_1197)	-	1025045..1025233 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
H1W84_RS05440 (STHERMO_1198)	murA	1025235..1026506 (-)	1272	WP_014608377.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
H1W84_RS05445 (STHERMO_1199)	-	1026576..1026812 (-)	237	WP_002946959.1	DUF1146 family protein	-
H1W84_RS05450 (STHERMO_1201)	galE	1027000..1028013 (-)	1014	WP_014608379.1	UDP-glucose 4-epimerase GalE	-
H1W84_RS05455 (STHERMO_1202)	-	1028028..1028531 (-)	504	WP_224102963.1	DUF4832 domain-containing protein	-
H1W84_RS05460 (STHERMO_1203)	-	1028521..1028973 (-)	453	WP_011681214.1	hypothetical protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31774.44 Da
• Isoelectric Point: 10.0477

>NTDB_id=1131829 H1W84_RS05430 WP_014608376.1 1024102..1024983(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_1055]
MAKRETSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=1131829 H1W84_RS05430 WP_014608376.1 1024102..1024983(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_1055]
ATGGCAAAAAGAGAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTAGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594