Detailed information NTG1131587

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: H1W91_RS05550
• Genome accession: NZ_LR822032
• Coordinates: 1050676..1051557 (-)
• Length: 293 a.a.
• NCBI ID: WP_002953146.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1050
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1045676..1056557

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W91_RS05525 (STHERMO_1203)	vicR	1046375..1047082 (-)	708	WP_011227274.1	response regulator YycF	Regulator
H1W91_RS05530 (STHERMO_1205)	-	1047614..1048381 (+)	768	WP_011227275.1	amino acid ABC transporter ATP-binding protein	-
H1W91_RS05535 (STHERMO_1206)	-	1048393..1049226 (+)	834	WP_011226086.1	transporter substrate-binding domain-containing protein	-
H1W91_RS05540 (STHERMO_1207)	-	1049244..1049942 (+)	699	WP_180477009.1	amino acid ABC transporter permease	-
H1W91_RS05545 (STHERMO_1208)	-	1049954..1050604 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
H1W91_RS05550 (STHERMO_1209)	endA	1050676..1051557 (-)	882	WP_002953146.1	DNA/RNA non-specific endonuclease	Machinery gene
H1W91_RS05555 (STHERMO_1210)	-	1051619..1051807 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
H1W91_RS05560 (STHERMO_1211)	murA	1051809..1053080 (-)	1272	WP_180477010.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
H1W91_RS05565 (STHERMO_1212)	-	1053150..1053386 (-)	237	WP_002946959.1	DUF1146 family protein	-
H1W91_RS05570 (STHERMO_1213)	galE	1053574..1054587 (-)	1014	WP_002946961.1	UDP-glucose 4-epimerase GalE	-
H1W91_RS05575 (STHERMO_1214)	-	1054602..1055057 (-)	456	WP_180477011.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31773.54 Da
• Isoelectric Point: 10.2316

>NTDB_id=1131587 H1W91_RS05550 WP_002953146.1 1050676..1051557(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_1050]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRKVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=1131587 H1W91_RS05550 WP_002953146.1 1050676..1051557(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_1050]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGAAAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGGGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594