Detailed information NTG1131350

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: H1X63_RS05695
• Genome accession: NZ_LR822027
• Coordinates: 1078390..1079271 (-)
• Length: 293 a.a.
• NCBI ID: WP_084828863.1
• Uniprot ID: A0A0E2QH56
• Organism: Streptococcus thermophilus isolate STH_CIRM_998
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1073390..1084271

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1X63_RS05660 (STHERMO_1223)	-	1073470..1074120 (+)	651	WP_179971939.1	amino acid ABC transporter permease	-
H1X63_RS05665 (STHERMO_1225)	-	1074184..1075440 (-)	1257	WP_179971940.1	ISL3 family transposase	-
H1X63_RS05670 (STHERMO_1226)	-	1075572..1076048 (-)	477	WP_179971941.1	transposase	-
H1X63_RS11270	-	1076091..1076240 (+)	150	WP_179973008.1	hypothetical protein	-
H1X63_RS05680	-	1076302..1076829 (+)	528	WP_179971942.1	HdeD family acid-resistance protein	-
H1X63_RS10690 (STHERMO_1230)	-	1076958..1078215 (-)	1258	Protein_1063	ISL3 family transposase	-
H1X63_RS05695 (STHERMO_1231)	endA	1078390..1079271 (-)	882	WP_084828863.1	DNA/RNA non-specific endonuclease	Machinery gene
H1X63_RS05700 (STHERMO_1232)	-	1079333..1079521 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
H1X63_RS05705 (STHERMO_1233)	murA	1079523..1080794 (-)	1272	WP_179971943.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
H1X63_RS05710 (STHERMO_1234)	-	1080864..1081100 (-)	237	WP_002946959.1	DUF1146 family protein	-
H1X63_RS05715 (STHERMO_1235)	galE	1081288..1082301 (-)	1014	WP_179971944.1	UDP-glucose 4-epimerase GalE	-
H1X63_RS05720 (STHERMO_1236)	-	1082316..1083725 (-)	1410	WP_415669551.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31768.48 Da
• Isoelectric Point: 10.0031

>NTDB_id=1131350 H1X63_RS05695 WP_084828863.1 1078390..1079271(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_998]
MAKGKTSLTNKQKRQFVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNYLTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINGNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDNSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=1131350 H1X63_RS05695 WP_084828863.1 1078390..1079271(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_998]
ATGGCAAAAGGAAAAACATCTTTGACAAATAAACAGAAACGTCAGTTCGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGCAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGAAAAT
CTAATAAATCCATTAAATCTAATTATTTAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGAGCCTATATTATTAATGGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCTTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAATTCTACAGGTCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCTTGATTTATGAAGGAGAGAACCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGATC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATAACCCTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterProScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (98-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	75.893	76.451	0.58
endA	Streptococcus pneumoniae D39	75.893	76.451	0.58
endA	Streptococcus pneumoniae R6	75.893	76.451	0.58
endA	Streptococcus pneumoniae TIGR4	75.893	76.451	0.58