Detailed information NTG1131030

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: H0510_RS05355
• Genome accession: NZ_LR822019
• Coordinates: 1010756..1011637 (-)
• Length: 293 a.a.
• NCBI ID: WP_022096754.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_772
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1005756..1016637

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0510_RS05330 (STHERMO_1171)	vicR	1006461..1007168 (-)	708	WP_173940375.1	response regulator YycF	Regulator
H0510_RS05335 (STHERMO_1173)	-	1007694..1008461 (+)	768	WP_179966655.1	amino acid ABC transporter ATP-binding protein	-
H0510_RS05340 (STHERMO_1174)	-	1008473..1009306 (+)	834	WP_002953142.1	transporter substrate-binding domain-containing protein	-
H0510_RS05345 (STHERMO_1175)	-	1009324..1010022 (+)	699	WP_011226087.1	amino acid ABC transporter permease	-
H0510_RS05350 (STHERMO_1176)	-	1010034..1010684 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
H0510_RS05355 (STHERMO_1177)	endA	1010756..1011637 (-)	882	WP_022096754.1	DNA/RNA non-specific endonuclease	Machinery gene
H0510_RS05360 (STHERMO_1178)	-	1011699..1011887 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
H0510_RS05365 (STHERMO_1179)	murA	1011889..1013160 (-)	1272	WP_022096753.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
H0510_RS05370 (STHERMO_1180)	-	1013230..1013466 (-)	237	WP_002946959.1	DUF1146 family protein	-
H0510_RS05375 (STHERMO_1181)	galE	1013654..1014667 (-)	1014	WP_002946961.1	UDP-glucose 4-epimerase GalE	-
H0510_RS09570 (STHERMO_1183)	-	1014900..1015298 (-)	399	WP_332068245.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31813.61 Da
• Isoelectric Point: 10.1789

>NTDB_id=1131030 H0510_RS05355 WP_022096754.1 1010756..1011637(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_772]
MAKRKTSLTNKQKRQLVTLIIAVLIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSINSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=1131030 H0510_RS05355 WP_022096754.1 1010756..1011637(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_772]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGTTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAATAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CCAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	70.635	86.007	0.608
endA	Streptococcus pneumoniae D39	70.635	86.007	0.608
endA	Streptococcus pneumoniae R6	70.635	86.007	0.608
endA	Streptococcus pneumoniae TIGR4	70.635	86.007	0.608