Detailed information NTG1130559

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: H0503_RS05410
• Genome accession: NZ_LR822009
• Coordinates: 1030655..1031536 (-)
• Length: 293 a.a.
• NCBI ID: WP_011681210.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_19
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1025655..1036536

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0503_RS05385 (STHERMO_1204)	vicR	1026359..1027066 (-)	708	WP_011681206.1	response regulator YycF	Regulator
H0503_RS05390 (STHERMO_1205)	-	1027593..1028360 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
H0503_RS05395 (STHERMO_1206)	-	1028372..1029205 (+)	834	WP_014608373.1	transporter substrate-binding domain-containing protein	-
H0503_RS05400 (STHERMO_1207)	-	1029223..1029921 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
H0503_RS05405 (STHERMO_1208)	-	1029933..1030583 (+)	651	WP_014608375.1	amino acid ABC transporter permease	-
H0503_RS05410 (STHERMO_1209)	endA	1030655..1031536 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
H0503_RS05415 (STHERMO_1210)	-	1031598..1031786 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
H0503_RS05420 (STHERMO_1211)	murA	1031788..1033059 (-)	1272	WP_179971400.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
H0503_RS05425 (STHERMO_1212)	-	1033129..1033365 (-)	237	WP_002946959.1	DUF1146 family protein	-
H0503_RS05430 (STHERMO_1214)	galE	1033553..1034566 (-)	1014	WP_011681212.1	UDP-glucose 4-epimerase GalE	-
H0503_RS05435 (STHERMO_1215)	-	1034581..1035036 (-)	456	WP_024009932.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31773.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=1130559 H0503_RS05410 WP_011681210.1 1030655..1031536(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_19]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=1130559 H0503_RS05410 WP_011681210.1 1030655..1031536(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_19]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTAGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594