Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   GPW69_RS06770 Genome accession   NZ_LR738724
Coordinates   1371901..1372740 (-) Length   279 a.a.
NCBI ID   WP_029171223.1    Uniprot ID   -
Organism   Streptococcus suis isolate 9401240     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1366901..1377740
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW69_RS06755 uidA 1367262..1369061 (-) 1800 WP_074391849.1 beta-glucuronidase -
  GPW69_RS06760 - 1369077..1370105 (-) 1029 WP_074391848.1 sugar kinase -
  GPW69_RS06765 - 1370161..1371714 (-) 1554 WP_024394643.1 MFS transporter -
  GPW69_RS06770 endA 1371901..1372740 (-) 840 WP_029171223.1 DNA/RNA non-specific endonuclease Machinery gene
  GPW69_RS06775 - 1372770..1372961 (-) 192 WP_012775177.1 DNA-directed RNA polymerase subunit beta -
  GPW69_RS06780 murA 1372954..1374237 (-) 1284 WP_074391847.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  GPW69_RS06785 - 1374261..1374485 (-) 225 WP_012775178.1 DUF1146 family protein -
  GPW69_RS06790 - 1374545..1374961 (-) 417 WP_002936007.1 F0F1 ATP synthase subunit epsilon -
  GPW69_RS06795 atpD 1374971..1376377 (-) 1407 WP_024407431.1 F0F1 ATP synthase subunit beta -
  GPW69_RS06800 - 1376397..1377275 (-) 879 WP_002936012.1 F0F1 ATP synthase subunit gamma -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 30180.33 Da        Isoelectric Point: 5.9494

>NTDB_id=1129598 GPW69_RS06770 WP_029171223.1 1371901..1372740(-) (endA) [Streptococcus suis isolate 9401240]
MTKKNVKKQAMSLLSLLATIVVVAGGYLLSDNKSSNVADYSYYVNQSKASEGTPSQELASSVLTEDVKKQLGNSIEWNGA
GAFIINGNQTDLDASVASVPYGDNKTKTVQGETVPTVANALLAKSTRQYKDREETGNGRTSWTPAGWHQVHDLTGEYDHA
VDRGHLLGYALIGGLSGFDASTSNPKNIAVQTAWSNQANDQTSTGQNYFESQIRRALDKNKRVRYRVTLVYAESEDLVPV
GSHLEAKAADGSLEFNVFVPNVQSGLSINYHSGEITVNE

Nucleotide


Download         Length: 840 bp        

>NTDB_id=1129598 GPW69_RS06770 WP_029171223.1 1371901..1372740(-) (endA) [Streptococcus suis isolate 9401240]
ATGACGAAGAAAAATGTAAAAAAACAAGCAATGAGTCTGCTCAGCTTATTGGCTACGATTGTTGTAGTAGCGGGTGGCTA
TCTTTTAAGCGATAACAAGAGCAGTAATGTTGCGGATTATTCCTATTATGTCAATCAGTCTAAGGCAAGTGAAGGCACAC
CTAGTCAGGAACTGGCTAGTTCGGTATTGACAGAAGATGTAAAAAAGCAACTGGGGAATTCGATTGAATGGAATGGTGCT
GGAGCATTTATTATTAACGGAAATCAAACGGATTTAGATGCCTCGGTTGCCAGTGTTCCTTATGGTGATAATAAGACAAA
AACAGTCCAGGGAGAAACGGTTCCAACAGTAGCCAATGCGCTTTTAGCCAAATCTACACGTCAGTATAAGGACCGTGAAG
AAACAGGAAACGGTCGGACTTCTTGGACACCTGCGGGTTGGCACCAGGTCCATGATTTAACTGGAGAATATGACCATGCA
GTGGACCGTGGTCACCTCCTAGGTTATGCTTTGATTGGTGGATTGTCTGGTTTCGATGCTTCAACCAGCAATCCTAAGAA
TATTGCAGTTCAAACAGCTTGGTCCAACCAAGCTAACGACCAAACTTCAACTGGGCAGAATTATTTTGAAAGTCAGATTC
GGCGGGCCTTGGATAAAAATAAGCGTGTCCGCTATCGTGTGACCTTGGTGTATGCTGAGAGTGAAGACCTTGTTCCAGTC
GGAAGTCATCTAGAGGCAAAAGCAGCAGATGGTAGCCTAGAGTTCAATGTGTTCGTTCCAAATGTGCAGAGTGGTCTCAG
TATCAACTATCATAGTGGGGAAATTACGGTGAATGAATAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(81-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

70.763

84.588

0.599
  endA Streptococcus pneumoniae D39

70.763

84.588

0.599
  endA Streptococcus pneumoniae R6

70.763

84.588

0.599
  endA Streptococcus pneumoniae TIGR4

70.763

84.588

0.599

Multiple sequence alignment