Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   GPW68_RS04515 Genome accession   NZ_LR738723
Coordinates   894441..895280 (+) Length   279 a.a.
NCBI ID   WP_012028260.1    Uniprot ID   A0A2K1T148
Organism   Streptococcus suis isolate GD-0088     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 889441..900280
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW68_RS04485 - 889906..890784 (+) 879 WP_002936012.1 F0F1 ATP synthase subunit gamma -
  GPW68_RS04490 atpD 890804..892210 (+) 1407 WP_002936008.1 F0F1 ATP synthase subunit beta -
  GPW68_RS04495 - 892220..892636 (+) 417 WP_002936007.1 F0F1 ATP synthase subunit epsilon -
  GPW68_RS04500 - 892696..892920 (+) 225 WP_012775178.1 DUF1146 family protein -
  GPW68_RS04505 murA 892944..894227 (+) 1284 WP_074389068.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  GPW68_RS04510 - 894220..894411 (+) 192 WP_074389067.1 DNA-directed RNA polymerase subunit beta -
  GPW68_RS04515 endA 894441..895280 (+) 840 WP_012028260.1 DNA/RNA non-specific endonuclease Machinery gene
  GPW68_RS04520 - 895467..897020 (+) 1554 WP_074389066.1 MFS transporter -
  GPW68_RS04525 - 897076..898104 (+) 1029 WP_074389065.1 sugar kinase -
  GPW68_RS04530 uidA 898120..899919 (+) 1800 WP_024405788.1 beta-glucuronidase -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 30190.37 Da        Isoelectric Point: 6.2370

>NTDB_id=1129552 GPW68_RS04515 WP_012028260.1 894441..895280(+) (endA) [Streptococcus suis isolate GD-0088]
MAKKNVKKQAMSLLSLLATIVVVAGGYLLSDNKSSNVADYSYYVNQSKASEGTPNQELASSVLTEDVKKQLGNSIEWNSA
GAFIINGNQTDLDASVASVPYGDNKTKTVQGETVPTVANALLAKSTRQYKDREETGNGRTSWTPAGWHQIHDLTGEYDHA
VDRGHLLGYALIGGLSGFDASTSNPKNIAVQTAWSNQANDQTSTGQNYFESQIRRALDKNKRVRYRVTLVYAESEDLVPV
GSHLEAKAADGSLEFNVFVPNVQSGLSINYHSGEIAVNQ

Nucleotide


Download         Length: 840 bp        

>NTDB_id=1129552 GPW68_RS04515 WP_012028260.1 894441..895280(+) (endA) [Streptococcus suis isolate GD-0088]
ATGGCGAAGAAAAATGTAAAAAAACAAGCAATGAGTCTGCTCAGCTTATTGGCTACGATTGTTGTAGTAGCGGGTGGCTA
TCTTTTAAGTGATAACAAGAGTAGCAACGTTGCTGATTATTCCTATTATGTCAATCAGTCTAAGGCAAGTGAAGGCACAC
CTAATCAGGAACTGGCTAGTTCGGTATTGACAGAAGATGTAAAAAAGCAACTGGGAAATTCGATTGAATGGAATAGTGCT
GGAGCGTTTATTATTAACGGGAATCAAACGGATTTAGATGCATCGGTTGCCAGTGTTCCTTATGGTGATAATAAGACAAA
AACAGTCCAGGGAGAAACGGTTCCAACAGTAGCCAATGCGCTTTTAGCTAAATCTACACGTCAGTATAAGGATCGTGAAG
AAACAGGAAATGGTCGAACTTCTTGGACACCTGCGGGTTGGCATCAGATCCATGATTTAACTGGAGAATATGACCATGCA
GTGGACCGTGGTCACCTCCTAGGTTATGCTTTGATTGGTGGATTGTCTGGCTTCGATGCTTCAACCAGCAATCCTAAGAA
TATTGCAGTTCAAACAGCTTGGTCCAACCAAGCTAACGACCAAACTTCAACTGGGCAGAATTATTTTGAAAGTCAGATTC
GGCGGGCCTTGGATAAAAATAAGCGTGTCCGCTATCGTGTGACCTTGGTGTATGCTGAGAGTGAAGACCTTGTTCCTGTC
GGAAGTCATCTAGAGGCAAAAGCAGCAGATGGTAGCCTAGAGTTCAATGTGTTCGTTCCAAATGTGCAGAGTGGTCTCAG
TATCAACTATCATAGTGGGGAAATTGCAGTAAATCAATAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(81-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2K1T148

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

69.492

84.588

0.588
  endA Streptococcus pneumoniae D39

69.492

84.588

0.588
  endA Streptococcus pneumoniae R6

69.492

84.588

0.588
  endA Streptococcus pneumoniae TIGR4

69.492

84.588

0.588

Multiple sequence alignment