Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   GPW48_RS06280 Genome accession   NZ_LR738720
Coordinates   1216834..1217673 (-) Length   279 a.a.
NCBI ID   WP_024417501.1    Uniprot ID   -
Organism   Streptococcus suis isolate GD-0001     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1211834..1222673
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW48_RS06265 uidA 1212172..1213971 (-) 1800 WP_024417499.1 beta-glucuronidase -
  GPW48_RS06270 - 1213987..1215015 (-) 1029 WP_013730404.1 sugar kinase -
  GPW48_RS06275 - 1215071..1216647 (-) 1577 Protein_1181 MFS transporter -
  GPW48_RS06280 endA 1216834..1217673 (-) 840 WP_024417501.1 DNA/RNA non-specific endonuclease Machinery gene
  GPW48_RS06285 - 1217703..1217894 (-) 192 WP_002936005.1 DNA-directed RNA polymerase subunit beta -
  GPW48_RS06290 murA 1217887..1219170 (-) 1284 WP_024417502.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  GPW48_RS06295 - 1219195..1219419 (-) 225 WP_024387485.1 DUF1146 family protein -
  GPW48_RS06300 - 1219479..1219895 (-) 417 WP_002936007.1 F0F1 ATP synthase subunit epsilon -
  GPW48_RS06305 atpD 1219905..1221311 (-) 1407 WP_024417504.1 F0F1 ATP synthase subunit beta -
  GPW48_RS06310 - 1221331..1222209 (-) 879 WP_002936012.1 F0F1 ATP synthase subunit gamma -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 30187.41 Da        Isoelectric Point: 6.2370

>NTDB_id=1129396 GPW48_RS06280 WP_024417501.1 1216834..1217673(-) (endA) [Streptococcus suis isolate GD-0001]
MAKKNVRKQAMSLLSLLATIVVVAGGYLLSDNKSSNVADYSYYVNQSKASEGIPSQELASSVLTEDVKKQLGNSIEWNGA
GAFIINGNQTDLDASVASVPYGDNKTKTVQGETVPTVANALLAKSTRQYKDREETGNGRTSWTPAGWHQIHDLTGEYDHA
VDRGHLLGYALIGGLSGFDASTSNPKNIAVQTAWSNQANDQTSTGQNYFESQIRRALDKNKRIRYRVTLVYAESEDLVPV
GSHLEAKAADGSLEFNVFVPNVQSGLSINYHSGEIAVNQ

Nucleotide


Download         Length: 840 bp        

>NTDB_id=1129396 GPW48_RS06280 WP_024417501.1 1216834..1217673(-) (endA) [Streptococcus suis isolate GD-0001]
ATGGCGAAGAAAAATGTAAGAAAACAAGCAATGAGTCTGCTCAGCTTATTGGCTACGATTGTTGTCGTAGCGGGTGGCTA
TCTTTTAAGTGATAACAAGAGCAGTAACGTTGCTGATTATTCCTATTATGTCAATCAGTCTAAGGCAAGTGAAGGCATAC
CTAGTCAGGAACTGGCTAGTTCGGTATTGACAGAAGATGTAAAAAAGCAACTGGGGAATTCGATTGAATGGAATGGCGCT
GGAGCATTTATTATTAACGGTAATCAAACAGATTTAGATGCATCGGTTGCCAGTGTACCTTATGGTGATAATAAGACAAA
GACAGTCCAGGGAGAAACGGTTCCAACAGTAGCCAATGCGCTTTTAGCTAAATCTACACGTCAGTATAAGGATCGTGAAG
AAACAGGAAATGGTCGAACTTCTTGGACACCTGCGGGTTGGCATCAGATCCATGATTTAACTGGAGAATATGACCATGCA
GTGGACCGTGGTCACCTCCTAGGTTATGCTTTGATTGGTGGATTGTCTGGCTTCGATGCTTCAACCAGCAATCCTAAGAA
TATTGCAGTTCAAACAGCTTGGTCCAACCAAGCTAACGACCAAACTTCAACTGGGCAGAATTATTTTGAAAGTCAGATTC
GGCGGGCCTTGGATAAAAATAAGCGTATCCGCTATCGTGTGACCTTGGTGTATGCTGAGAGTGAAGACCTTGTTCCTGTC
GGAAGCCATCTAGAGGCAAAAGCAGCAGATGGTAGCCTAGAGTTCAATGTGTTCGTTCCAAATGTGCAGAGTGGTCTCAG
TATCAACTATCATAGTGGGGAAATTGCAGTAAATCAATAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(81-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

69.915

84.588

0.591
  endA Streptococcus pneumoniae D39

69.915

84.588

0.591
  endA Streptococcus pneumoniae R6

69.915

84.588

0.591
  endA Streptococcus pneumoniae TIGR4

69.915

84.588

0.591

Multiple sequence alignment