Detailed information NTG1128133

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: FGL17_RS05685
• Genome accession: NZ_LR594052
• Coordinates: 1155610..1156491 (-)
• Length: 293 a.a.
• NCBI ID: WP_003082810.1
• Uniprot ID: A0A4V0H9N4
• Organism: Streptococcus porcinus strain NCTC10924
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1150610..1161491

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL17_RS05665 (NCTC10924_01140)	-	1150822..1151193 (-)	372	WP_003083287.1	OsmC family protein	-
FGL17_RS05670 (NCTC10924_01141)	pheT	1151284..1153689 (-)	2406	WP_093958710.1	phenylalanine--tRNA ligase subunit beta	-
FGL17_RS05675 (NCTC10924_01142)	-	1153704..1154228 (-)	525	WP_003083083.1	GNAT family N-acetyltransferase	-
FGL17_RS05680 (NCTC10924_01143)	pheS	1154274..1155317 (-)	1044	WP_039984576.1	phenylalanine--tRNA ligase subunit alpha	-
FGL17_RS05685 (NCTC10924_01144)	endA	1155610..1156491 (-)	882	WP_003082810.1	DNA/RNA non-specific endonuclease	Machinery gene
FGL17_RS05690 (NCTC10924_01145)	-	1156522..1156713 (-)	192	WP_172601601.1	DNA-directed RNA polymerase subunit beta	-
FGL17_RS05695 (NCTC10924_01146)	murA	1156713..1157984 (-)	1272	WP_003083400.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
FGL17_RS05700 (NCTC10924_01147)	-	1158059..1158283 (-)	225	WP_003085295.1	DUF1146 family protein	-
FGL17_RS05705 (NCTC10924_01148)	-	1158364..1158780 (-)	417	WP_003084986.1	F0F1 ATP synthase subunit epsilon	-
FGL17_RS05710 (NCTC10924_01149)	atpD	1158793..1160199 (-)	1407	WP_003085772.1	F0F1 ATP synthase subunit beta	-
FGL17_RS05715 (NCTC10924_01150)	-	1160317..1161195 (-)	879	WP_003084154.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 32556.77 Da
• Isoelectric Point: 10.4399

>NTDB_id=1128133 FGL17_RS05685 WP_003082810.1 1155610..1156491(-) (endA) [Streptococcus porcinus strain NCTC10924]
MSKKQPHFKKLNGILLALLITGLIAFTNGHYLASNNPLQQVLHAISGQGNNQKDSKNSTNPATPSYQLASSVLTPQVKKQ
LGQKIVWNGAGAFIVNNNKTNLKAKVSSLPYANNEVKIVESKKVPFRANALLTKSTRQYRNRNETGNGYTFWKPVGWHQI
HGLPGEYDHAVDRGHLLGYALIGGLKGYDASTSNPSNIAVQMAWANQAYLSDSTGQNYYETLIRKALDRNKRVRYRVTLL
YEKNNIISSGSHLEAKSDDGRLEFNVFVPNVQKGLRVNYQTGQVEQQSDQKAS

Nucleotide

• Length: 882 bp

>NTDB_id=1128133 FGL17_RS05685 WP_003082810.1 1155610..1156491(-) (endA) [Streptococcus porcinus strain NCTC10924]
ATGTCTAAAAAACAGCCACATTTCAAAAAGCTTAATGGAATTCTGCTAGCTCTGCTCATTACTGGGCTAATAGCCTTCAC
CAATGGCCATTACCTTGCATCCAATAACCCATTGCAGCAAGTGTTACATGCTATTTCTGGTCAAGGGAACAATCAAAAAG
ACTCTAAAAATTCGACTAATCCTGCCACACCTAGTTATCAGTTAGCTAGCTCGGTGCTTACCCCGCAAGTGAAAAAGCAA
TTAGGTCAGAAAATTGTGTGGAATGGTGCAGGTGCTTTTATCGTAAATAACAATAAAACTAATTTGAAGGCGAAAGTTTC
AAGTTTGCCTTATGCAAATAATGAAGTCAAGATAGTTGAGAGTAAGAAAGTGCCTTTTAGAGCCAACGCTTTGTTAACCA
AATCAACAAGACAATATCGTAATCGTAATGAAACTGGTAATGGTTATACCTTCTGGAAGCCAGTGGGTTGGCATCAAATC
CACGGCTTGCCAGGTGAATATGATCACGCTGTTGATAGAGGTCATTTATTGGGTTATGCCTTGATAGGTGGCTTAAAAGG
CTACGATGCTTCGACCAGCAATCCAAGCAATATTGCAGTACAAATGGCCTGGGCAAACCAGGCTTACCTCTCAGATTCAA
CAGGACAAAATTATTATGAAACTTTAATCAGAAAAGCTTTAGATAGAAATAAACGAGTTCGTTATAGAGTGACCTTACTT
TATGAAAAGAATAATATTATTTCTAGTGGTAGTCACTTAGAAGCAAAATCGGATGATGGTCGTTTGGAATTTAATGTTTT
TGTACCAAATGTTCAAAAAGGGTTAAGGGTTAATTATCAAACAGGTCAAGTTGAGCAACAAAGTGATCAAAAAGCTAGCT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (97-246)

3D structure

• AlphaFold DB: A0A4V0H9N4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	68.018	75.768	0.515
endA	Streptococcus pneumoniae D39	68.018	75.768	0.515
endA	Streptococcus pneumoniae R6	68.018	75.768	0.515
endA	Streptococcus pneumoniae TIGR4	68.018	75.768	0.515