Detailed information NTG1128042

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: FGL20_RS05715
• Genome accession: NZ_LR594050
• Coordinates: 1161184..1162065 (-)
• Length: 293 a.a.
• NCBI ID: WP_003082810.1
• Uniprot ID: A0A4V0H9N4
• Organism: Streptococcus porcinus strain NCTC10925
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1156184..1167065

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL20_RS05695 (NCTC10925_01142)	-	1156396..1156767 (-)	372	WP_003083287.1	OsmC family protein	-
FGL20_RS05700 (NCTC10925_01143)	pheT	1156858..1159263 (-)	2406	WP_093958710.1	phenylalanine--tRNA ligase subunit beta	-
FGL20_RS05705 (NCTC10925_01144)	-	1159278..1159802 (-)	525	WP_003083083.1	GNAT family N-acetyltransferase	-
FGL20_RS05710 (NCTC10925_01145)	pheS	1159848..1160891 (-)	1044	WP_039984576.1	phenylalanine--tRNA ligase subunit alpha	-
FGL20_RS05715 (NCTC10925_01146)	endA	1161184..1162065 (-)	882	WP_003082810.1	DNA/RNA non-specific endonuclease	Machinery gene
FGL20_RS05720 (NCTC10925_01147)	-	1162096..1162287 (-)	192	WP_172601601.1	DNA-directed RNA polymerase subunit beta	-
FGL20_RS05725 (NCTC10925_01148)	murA	1162287..1163558 (-)	1272	WP_003083400.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
FGL20_RS05730 (NCTC10925_01149)	-	1163633..1163857 (-)	225	WP_003085295.1	DUF1146 family protein	-
FGL20_RS05735 (NCTC10925_01150)	-	1163938..1164354 (-)	417	WP_003084986.1	F0F1 ATP synthase subunit epsilon	-
FGL20_RS05740 (NCTC10925_01151)	atpD	1164367..1165773 (-)	1407	WP_003085772.1	F0F1 ATP synthase subunit beta	-
FGL20_RS05745 (NCTC10925_01152)	-	1165891..1166769 (-)	879	WP_003084154.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 32556.77 Da
• Isoelectric Point: 10.4399

>NTDB_id=1128042 FGL20_RS05715 WP_003082810.1 1161184..1162065(-) (endA) [Streptococcus porcinus strain NCTC10925]
MSKKQPHFKKLNGILLALLITGLIAFTNGHYLASNNPLQQVLHAISGQGNNQKDSKNSTNPATPSYQLASSVLTPQVKKQ
LGQKIVWNGAGAFIVNNNKTNLKAKVSSLPYANNEVKIVESKKVPFRANALLTKSTRQYRNRNETGNGYTFWKPVGWHQI
HGLPGEYDHAVDRGHLLGYALIGGLKGYDASTSNPSNIAVQMAWANQAYLSDSTGQNYYETLIRKALDRNKRVRYRVTLL
YEKNNIISSGSHLEAKSDDGRLEFNVFVPNVQKGLRVNYQTGQVEQQSDQKAS

Nucleotide

• Length: 882 bp

>NTDB_id=1128042 FGL20_RS05715 WP_003082810.1 1161184..1162065(-) (endA) [Streptococcus porcinus strain NCTC10925]
ATGTCTAAAAAACAGCCACATTTCAAAAAGCTTAATGGAATTCTGCTAGCTCTGCTCATTACTGGGCTAATAGCCTTCAC
CAATGGCCATTACCTTGCATCCAATAACCCATTGCAGCAAGTGTTACATGCTATTTCTGGTCAAGGGAACAATCAAAAAG
ACTCTAAAAATTCGACTAATCCTGCCACACCTAGTTATCAGTTAGCTAGCTCGGTGCTTACCCCGCAAGTGAAAAAGCAA
TTAGGTCAGAAAATTGTGTGGAATGGTGCAGGTGCTTTTATCGTAAATAACAATAAAACTAATTTGAAGGCGAAAGTTTC
AAGTTTGCCTTATGCAAATAATGAAGTCAAGATAGTTGAGAGTAAGAAAGTGCCTTTTAGAGCCAACGCTTTGTTAACCA
AATCAACAAGACAATATCGTAATCGTAATGAAACTGGTAATGGTTATACCTTCTGGAAGCCAGTGGGTTGGCATCAAATC
CACGGCTTGCCAGGTGAATATGATCACGCTGTTGATAGAGGTCATTTATTGGGTTATGCCTTGATAGGTGGCTTAAAAGG
CTACGATGCTTCGACCAGCAATCCAAGCAATATTGCAGTACAAATGGCCTGGGCAAACCAGGCTTACCTCTCAGATTCAA
CAGGACAAAATTATTATGAAACTTTAATCAGAAAAGCTTTAGATAGAAATAAACGAGTTCGTTATAGAGTGACCTTACTT
TATGAAAAGAATAATATTATTTCTAGTGGTAGTCACTTAGAAGCAAAATCGGATGATGGTCGTTTGGAATTTAATGTTTT
TGTACCAAATGTTCAAAAAGGGTTAAGGGTTAATTATCAAACAGGTCAAGTTGAGCAACAAAGTGATCAAAAAGCTAGCT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (97-246)

3D structure

• AlphaFold DB: A0A4V0H9N4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	68.018	75.768	0.515
endA	Streptococcus pneumoniae D39	68.018	75.768	0.515
endA	Streptococcus pneumoniae R6	68.018	75.768	0.515
endA	Streptococcus pneumoniae TIGR4	68.018	75.768	0.515