Detailed information NTG1127920

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: FGL22_RS03880
• Genome accession: NZ_LR594048
• Coordinates: 744913..745779 (+)
• Length: 288 a.a.
• NCBI ID: WP_046159387.1
• Uniprot ID: A0A9X8XHZ8
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC11556
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 739913..750779

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL22_RS03855 (NCTC11556_00796)	atpD	740949..742355 (+)	1407	WP_003057452.1	F0F1 ATP synthase subunit beta	-
FGL22_RS03860 (NCTC11556_00797)	-	742368..742784 (+)	417	WP_003050138.1	F0F1 ATP synthase subunit epsilon	-
FGL22_RS03865 (NCTC11556_00798)	-	743113..743349 (+)	237	WP_274047614.1	DUF1146 family protein	-
FGL22_RS03870 (NCTC11556_00799)	murA	743414..744685 (+)	1272	WP_015016870.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
FGL22_RS03875 (NCTC11556_00800)	-	744689..744877 (+)	189	WP_046177788.1	DNA-directed RNA polymerase subunit beta	-
FGL22_RS03880 (NCTC11556_00801)	endA	744913..745779 (+)	867	WP_046159387.1	DNA/RNA non-specific endonuclease	Machinery gene
FGL22_RS03885 (NCTC11556_00802)	pheS	746062..747105 (+)	1044	WP_065355257.1	phenylalanine--tRNA ligase subunit alpha	-
FGL22_RS03890 (NCTC11556_00803)	pheT	747315..749720 (+)	2406	WP_138129358.1	phenylalanine--tRNA ligase subunit beta	-
FGL22_RS03895 (NCTC11556_00804)	-	749831..750208 (+)	378	WP_046177790.1	OsmC family protein	-
FGL22_RS03900 (NCTC11556_00805)	-	750201..750587 (+)	387	WP_046177791.1	DUF1722 domain-containing protein	-

Sequence

Protein

• Length: 288 a.a.
• Molecular weight: 31916.95 Da
• Isoelectric Point: 10.1381

>NTDB_id=1127920 FGL22_RS03880 WP_046159387.1 744913..745779(+) (endA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11556]
MLTRKKRKRVLNSFLLILLVLGSSYLAKSDFIASNHPIKQIYRTVLGDKGESSSESKEVYSEVPTEALSASVLTKSIKEQ
LGSNIEWNGAGAYIINRNKTDLNASVASLPYANNETKWVQGQKVPTRANALLTKSTRQYRNRYQTDNAYRTFKPAGWHQL
HHLKGNYDHAVDRGHLLGYALVGGLKGFDASTSNPDNIATQLSWANQADKPYSTGQNYYEGLVRRALDKGKRVRYRVTLL
YDGDNLLASGSQLEAKSADGSLAFNVFVPNVQAGLTVDYRTGQIAINP

Nucleotide

• Length: 867 bp

>NTDB_id=1127920 FGL22_RS03880 WP_046159387.1 744913..745779(+) (endA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11556]
ATGTTAACAAGGAAAAAACGAAAAAGGGTGCTTAATTCCTTCTTATTGATTTTGTTAGTGTTGGGGTCTAGTTACCTTGC
TAAGAGTGATTTCATAGCTAGCAATCATCCTATTAAGCAAATTTATCGTACCGTTTTGGGAGATAAGGGTGAATCATCAT
CAGAATCAAAAGAAGTCTATAGTGAGGTTCCCACAGAAGCCCTATCCGCTTCTGTCTTGACCAAATCCATTAAGGAACAA
TTAGGTTCCAATATTGAATGGAATGGAGCAGGCGCCTATATTATCAACAGGAACAAAACAGATTTAAACGCAAGCGTAGC
CAGTCTGCCCTATGCCAATAATGAAACCAAATGGGTCCAAGGACAAAAGGTTCCTACTAGAGCTAATGCCTTACTTACTA
AGTCGACACGACAGTATCGAAATCGCTATCAAACGGACAATGCTTATCGTACCTTCAAGCCTGCTGGTTGGCACCAATTA
CATCACTTAAAAGGAAATTATGACCACGCAGTTGATAGAGGACATTTGCTAGGTTATGCTTTAGTCGGTGGACTGAAAGG
TTTTGATGCATCTACCAGTAATCCTGATAACATTGCTACTCAACTAAGTTGGGCCAATCAAGCAGATAAACCCTATTCGA
CAGGTCAAAATTACTATGAAGGATTAGTACGTCGTGCATTGGATAAGGGCAAAAGGGTACGTTATCGTGTTACCTTGCTT
TATGATGGTGATAACCTGTTAGCCAGTGGTAGCCAGTTAGAAGCCAAATCTGCCGATGGGAGTTTAGCATTTAACGTGTT
TGTTCCAAATGTTCAAGCAGGGCTGACGGTTGATTATCGAACAGGACAGATTGCCATCAATCCCTAG

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (121-246)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	62.338	80.208	0.5
endA	Streptococcus pneumoniae D39	62.338	80.208	0.5
endA	Streptococcus pneumoniae R6	62.338	80.208	0.5
endA	Streptococcus pneumoniae TIGR4	62.338	80.208	0.5