Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   FGL12_RS03790 Genome accession   NZ_LR594041
Coordinates   789549..790388 (+) Length   279 a.a.
NCBI ID   WP_138101165.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC9124     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 784549..795388
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL12_RS03765 (NCTC9124_00756) tuf 785412..786608 (+) 1197 WP_009754926.1 elongation factor Tu -
  FGL12_RS03770 (NCTC9124_00757) tpiA 786882..787640 (+) 759 WP_012000225.1 triose-phosphate isomerase -
  FGL12_RS03775 (NCTC9124_00758) - 787770..788003 (+) 234 WP_041789607.1 DUF1146 family protein -
  FGL12_RS03780 (NCTC9124_00759) murA 788043..789323 (+) 1281 WP_012000226.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  FGL12_RS03785 (NCTC9124_00760) - 789316..789504 (+) 189 WP_020992673.1 DNA-directed RNA polymerase subunit beta -
  FGL12_RS03790 (NCTC9124_00761) endA 789549..790388 (+) 840 WP_138101165.1 DNA/RNA non-specific endonuclease Machinery gene
  FGL12_RS03795 (NCTC9124_00762) - 790604..791305 (-) 702 WP_012000228.1 alpha/beta hydrolase-fold protein -
  FGL12_RS03800 (NCTC9124_00763) - 791286..792314 (-) 1029 WP_041789612.1 ABC transporter substrate-binding protein -
  FGL12_RS03805 (NCTC9124_00764) - 792459..793214 (-) 756 WP_012000231.1 ABC transporter ATP-binding protein -
  FGL12_RS03810 (NCTC9124_00765) - 793216..794262 (-) 1047 WP_012000232.1 iron ABC transporter permease -
  FGL12_RS10990 - 794555..794662 (+) 108 Protein_732 DNA-entry nuclease -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 30839.57 Da        Isoelectric Point: 10.0956

>NTDB_id=1127487 FGL12_RS03790 WP_138101165.1 789549..790388(+) (endA) [Streptococcus gordonii strain NCTC9124]
MKKKQEEKLFQSIVGLILALVLIAGANYFSNHQNQDKIKSNPQVQRTGRRDISTPEQALSQSVLTDSVRKQLKGNIEWNQ
AGAFIINGNKTDLNADIASQPYAQNQTKSVQGQLVPIIGNALLSKQTRQYKNREETGNGTTSWVPAGWHQVRNLSGDFNH
AVDRGHLLAYSIVGGLKNFDASTSSPENIAVQTAWANQANSPSSTGQNFYESLIRKALDKKKRVRYRVTLIYANPDDLIA
VGSHLEAKSSDGSLEFNVFVPNVQTGIRINYRTGEVTVE

Nucleotide


Download         Length: 840 bp        

>NTDB_id=1127487 FGL12_RS03790 WP_138101165.1 789549..790388(+) (endA) [Streptococcus gordonii strain NCTC9124]
ATGAAGAAGAAACAAGAAGAGAAACTCTTTCAAAGCATAGTAGGACTGATTCTGGCACTTGTTCTGATAGCTGGTGCTAA
TTATTTCTCAAACCATCAGAATCAGGATAAGATAAAGTCTAATCCACAGGTTCAAAGAACAGGAAGAAGGGATATCTCAA
CCCCCGAGCAAGCACTATCTCAGAGTGTGCTGACTGATTCTGTTCGCAAGCAATTAAAAGGCAACATAGAATGGAATCAG
GCAGGTGCATTTATTATTAATGGCAACAAGACAGACCTGAATGCTGATATTGCCAGTCAGCCTTATGCACAAAATCAGAC
AAAGTCAGTTCAGGGACAGTTAGTACCAATAATTGGGAATGCTCTGCTTTCTAAACAGACTAGACAATACAAAAATCGAG
AAGAAACCGGAAACGGAACGACAAGTTGGGTTCCTGCTGGCTGGCATCAAGTGAGAAATCTTAGTGGAGATTTTAATCAT
GCAGTTGATCGAGGCCATTTATTAGCTTATTCTATAGTCGGAGGCTTAAAGAACTTCGATGCTTCTACAAGTAGCCCAGA
GAATATCGCTGTCCAAACGGCTTGGGCAAATCAGGCAAACAGTCCTTCATCTACTGGGCAAAATTTTTATGAAAGCTTGA
TTCGGAAGGCTTTGGATAAAAAGAAGAGAGTTCGTTATCGGGTAACCTTGATTTATGCTAATCCTGATGACTTGATAGCA
GTAGGCTCTCATTTAGAAGCAAAGTCCAGCGACGGAAGCCTCGAGTTTAATGTCTTCGTTCCAAATGTTCAAACCGGGAT
TCGTATCAACTATAGAACTGGAGAAGTAACAGTAGAGTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(82-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

67.857

80.287

0.545
  endA Streptococcus pneumoniae D39

67.857

80.287

0.545
  endA Streptococcus pneumoniae R6

67.857

80.287

0.545
  endA Streptococcus pneumoniae TIGR4

67.857

80.287

0.545

Multiple sequence alignment