Detailed information NTG1127297

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: FGL04_RS04310
• Genome accession: NZ_LR594035
• Coordinates: 792705..793574 (+)
• Length: 289 a.a.
• NCBI ID: WP_138068326.1
• Uniprot ID: A0A4U9Y3X1
• Organism: Streptococcus pseudoporcinus strain NCTC5385
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 787705..798574

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL04_RS04280 (NCTC5385_00928)	-	788000..788878 (+)	879	WP_138068323.1	F0F1 ATP synthase subunit gamma	-
FGL04_RS04285 (NCTC5385_00929)	atpD	788996..790402 (+)	1407	WP_007894308.1	F0F1 ATP synthase subunit beta	-
FGL04_RS04290 (NCTC5385_00930)	-	790415..790831 (+)	417	WP_138068324.1	F0F1 ATP synthase subunit epsilon	-
FGL04_RS04295 (NCTC5385_00931)	-	790913..791137 (+)	225	WP_037598858.1	DUF1146 family protein	-
FGL04_RS04300 (NCTC5385_00932)	murA	791212..792483 (+)	1272	WP_138068325.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
FGL04_RS04305 (NCTC5385_00933)	-	792483..792674 (+)	192	WP_171011270.1	DNA-directed RNA polymerase subunit beta	-
FGL04_RS04310 (NCTC5385_00934)	endA	792705..793574 (+)	870	WP_138068326.1	DNA/RNA non-specific endonuclease	Machinery gene
FGL04_RS04315 (NCTC5385_00935)	pheS	793879..794922 (+)	1044	WP_171011241.1	phenylalanine--tRNA ligase subunit alpha	-
FGL04_RS04320 (NCTC5385_00936)	-	794967..795491 (+)	525	WP_138068328.1	GNAT family N-acetyltransferase	-
FGL04_RS04325 (NCTC5385_00937)	pheT	795506..797911 (+)	2406	WP_138068329.1	phenylalanine--tRNA ligase subunit beta	-
FGL04_RS04330 (NCTC5385_00938)	-	798002..798376 (+)	375	WP_138068330.1	OsmC family protein	-

Sequence

Protein

• Length: 289 a.a.
• Molecular weight: 32171.43 Da
• Isoelectric Point: 10.4558

>NTDB_id=1127297 FGL04_RS04310 WP_138068326.1 792705..793574(+) (endA) [Streptococcus pseudoporcinus strain NCTC5385]
MSKKQLNIQKLNGILLALFITGVIALTQSRHLASDNPLQQVLQIISGQEKTQKYSKNPTNPDTPSYQLASSVLTQQVKKQ
LGQKIEWNGAGAFIINNNRTALKVKVSSLPYANNDIKRVEGKQVPFRANALLAKSTRQYRNRNETGNGYTSWKPAGWHQI
HGLSGGYDHAIDRGHLLAYALIVGLKDYDASTSNPSNIAVQTAWANQAYLSDSTGQNYYETLIRKALDSGKRVRYRVTLL
YEKNNLVSSGSHLEAKANDGSLEFNVFVPNVQKGLKINYQTGQVKRHMN

Nucleotide

• Length: 870 bp

>NTDB_id=1127297 FGL04_RS04310 WP_138068326.1 792705..793574(+) (endA) [Streptococcus pseudoporcinus strain NCTC5385]
ATGTCCAAAAAACAGCTAAATATCCAAAAGCTCAATGGGATTCTGCTAGCTCTGTTCATTACTGGGGTAATAGCCTTAAC
GCAGAGCCGTCACCTTGCGTCTGATAACCCACTTCAGCAAGTATTACAGATTATTTCCGGTCAAGAGAAAACTCAAAAAT
ACTCCAAAAATCCGACGAATCCTGATACACCTAGTTATCAGTTAGCTAGTTCAGTGCTTACGCAACAAGTGAAAAAACAA
TTAGGTCAGAAGATTGAGTGGAATGGTGCTGGTGCTTTTATCATTAATAATAATAGGACCGCTTTGAAGGTAAAAGTTTC
AAGTTTACCTTATGCCAATAATGACATCAAGCGAGTTGAGGGTAAGCAAGTGCCTTTCAGAGCGAATGCTTTATTAGCTA
AATCAACAAGACAATACCGTAACCGCAATGAAACGGGGAATGGCTATACCTCTTGGAAGCCAGCGGGGTGGCATCAAATT
CATGGCTTGTCAGGTGGATATGATCATGCTATTGATAGGGGGCATTTACTAGCTTATGCATTGATAGTTGGCCTAAAAGA
TTATGACGCTTCTACCAGCAATCCAAGTAACATTGCAGTACAAACGGCCTGGGCAAACCAAGCTTACCTCTCAGATTCAA
CAGGTCAAAATTATTATGAAACCTTAATACGAAAAGCACTAGATAGTGGTAAACGGGTTCGTTACAGAGTGACCTTGCTT
TATGAGAAGAATAACCTTGTTTCTAGCGGTAGTCACTTAGAAGCAAAAGCTAATGATGGCAGTTTGGAATTTAATGTTTT
TGTGCCAAATGTTCAAAAAGGTTTAAAGATTAACTATCAAACAGGACAAGTTAAGCGACACATGAATTAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (98-246)

3D structure

• AlphaFold DB: A0A4U9Y3X1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	65.179	77.509	0.505
endA	Streptococcus pneumoniae D39	65.179	77.509	0.505
endA	Streptococcus pneumoniae R6	65.179	77.509	0.505
endA	Streptococcus pneumoniae TIGR4	65.179	77.509	0.505