Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   FGL00_RS03825 Genome accession   NZ_LR594034
Coordinates   744269..745135 (+) Length   288 a.a.
NCBI ID   WP_046159387.1    Uniprot ID   A0A9X8XHZ8
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 739269..750135
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL00_RS03800 (NCTC8546_00784) atpD 740305..741711 (+) 1407 WP_003057452.1 F0F1 ATP synthase subunit beta -
  FGL00_RS03805 (NCTC8546_00785) - 741724..742140 (+) 417 WP_003050138.1 F0F1 ATP synthase subunit epsilon -
  FGL00_RS03810 (NCTC8546_00786) - 742469..742705 (+) 237 WP_274047614.1 DUF1146 family protein -
  FGL00_RS03815 (NCTC8546_00787) murA 742770..744041 (+) 1272 WP_046159388.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  FGL00_RS03820 (NCTC8546_00788) - 744045..744233 (+) 189 WP_003057490.1 DNA-directed RNA polymerase subunit beta -
  FGL00_RS03825 (NCTC8546_00789) endA 744269..745135 (+) 867 WP_046159387.1 DNA/RNA non-specific endonuclease Machinery gene
  FGL00_RS03830 (NCTC8546_00790) pheS 745418..746461 (+) 1044 WP_138098329.1 phenylalanine--tRNA ligase subunit alpha -
  FGL00_RS03835 (NCTC8546_00791) pheT 746671..749076 (+) 2406 WP_138098331.1 phenylalanine--tRNA ligase subunit beta -
  FGL00_RS03840 (NCTC8546_00792) - 749186..749563 (+) 378 WP_003057473.1 OsmC family protein -
  FGL00_RS03845 (NCTC8546_00793) - 749556..749942 (+) 387 WP_138098333.1 DUF1722 domain-containing protein -

Sequence

Protein


Download         Length: 288 a.a.        Molecular weight: 31916.95 Da        Isoelectric Point: 10.1381

>NTDB_id=1127244 FGL00_RS03825 WP_046159387.1 744269..745135(+) (endA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546]
MLTRKKRKRVLNSFLLILLVLGSSYLAKSDFIASNHPIKQIYRTVLGDKGESSSESKEVYSEVPTEALSASVLTKSIKEQ
LGSNIEWNGAGAYIINRNKTDLNASVASLPYANNETKWVQGQKVPTRANALLTKSTRQYRNRYQTDNAYRTFKPAGWHQL
HHLKGNYDHAVDRGHLLGYALVGGLKGFDASTSNPDNIATQLSWANQADKPYSTGQNYYEGLVRRALDKGKRVRYRVTLL
YDGDNLLASGSQLEAKSADGSLAFNVFVPNVQAGLTVDYRTGQIAINP

Nucleotide


Download         Length: 867 bp        

>NTDB_id=1127244 FGL00_RS03825 WP_046159387.1 744269..745135(+) (endA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546]
ATGTTAACAAGGAAAAAACGAAAAAGGGTGCTTAATTCCTTCTTATTGATTTTGTTAGTGTTGGGGTCTAGTTACCTTGC
TAAGAGTGATTTCATAGCTAGCAATCATCCTATTAAGCAAATTTATCGTACCGTTTTGGGAGATAAGGGTGAATCATCAT
CAGAATCAAAAGAAGTCTATAGTGAGGTTCCCACAGAAGCCCTATCCGCTTCTGTCTTGACCAAATCCATTAAGGAACAA
TTAGGTTCCAATATTGAATGGAATGGAGCAGGCGCCTATATTATCAACAGGAACAAAACAGATTTAAACGCAAGCGTAGC
CAGTCTGCCCTATGCCAATAATGAAACCAAATGGGTCCAAGGACAAAAGGTTCCTACTAGAGCTAATGCCTTACTTACTA
AGTCGACACGACAGTATCGAAATCGCTATCAAACGGACAATGCTTATCGTACCTTCAAGCCTGCTGGTTGGCACCAATTA
CATCACTTAAAAGGAAATTATGACCACGCAGTTGATAGAGGACATTTGCTAGGTTATGCTTTAGTCGGTGGACTGAAAGG
TTTTGATGCATCTACCAGTAATCCTGATAACATTGCTACTCAACTAAGTTGGGCCAATCAAGCAGATAAACCCTATTCGA
CAGGTCAAAATTACTATGAAGGCTTAGTACGTCGTGCATTGGATAAGGGCAAAAGGGTCCGTTATCGTGTTACCTTGCTT
TATGATGGTGATAATCTGTTAGCCAGTGGCAGCCAGTTAGAGGCCAAATCTGCCGATGGGAGTTTAGCATTTAACGTGTT
TGTTCCAAATGTTCAAGCAGGGTTGACGGTTGATTATCGAACAGGACAGATTGCCATCAATCCCTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(121-246)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

62.338

80.208

0.5
  endA Streptococcus pneumoniae D39

62.338

80.208

0.5
  endA Streptococcus pneumoniae R6

62.338

80.208

0.5
  endA Streptococcus pneumoniae TIGR4

62.338

80.208

0.5

Multiple sequence alignment