Detailed information NTG1126580

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: E0F34_RS09665
• Genome accession: NZ_LR536843
• Coordinates: 1794024..1794848 (-)
• Length: 274 a.a.
• NCBI ID: WP_001862695.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1789024..1799848

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F34_RS09660 (SAMEA104035599_01844)	-	1792403..1793734 (-)	1332	WP_000390043.1	hemolysin family protein	-
E0F34_RS09665 (SAMEA104035599_01845)	endA	1794024..1794848 (-)	825	WP_001862695.1	DNA-entry nuclease EndA	Machinery gene
E0F34_RS09670 (SAMEA104035599_01846)	-	1794887..1795075 (-)	189	WP_001812859.1	DNA-directed RNA polymerase subunit beta	-
E0F34_RS09675 (SAMEA104035599_01847)	murA	1795068..1796351 (-)	1284	WP_000358027.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
E0F34_RS09680 (SAMEA104035599_01848)	-	1796375..1796605 (-)	231	WP_000250384.1	DUF1146 family protein	-
E0F34_RS09685 (SAMEA104035599_01849)	sepM	1796663..1797700 (-)	1038	WP_000727277.1	SepM family pheromone-processing serine protease	Regulator
E0F34_RS09690 (SAMEA104035599_01850)	coaD	1797684..1798172 (-)	489	WP_001862696.1	pantetheine-phosphate adenylyltransferase	-
E0F34_RS09695 (SAMEA104035599_01851)	rsmD	1798162..1798701 (-)	540	WP_061649878.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
E0F34_RS09700 (SAMEA104035599_01852)	asnA	1798766..1799758 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-

Sequence

Protein

• Length: 274 a.a.
• Molecular weight: 29977.61 Da
• Isoelectric Point: 9.9121

>NTDB_id=1126580 E0F34_RS09665 WP_001862695.1 1794024..1794848(-) (endA) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
MNKKTRQTLIGLLVLLLLSAGSYYIKQNELGNQAAKTKMSQKKQAPEAPSQELAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide

• Length: 825 bp

>NTDB_id=1126580 E0F34_RS09665 WP_001862695.1 1794024..1794848(-) (endA) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
ATGAACAAAAAAACAAGACAGACACTGATTGGACTGCTAGTGTTATTGCTTTTGTCTGCAGGGAGCTATTATATTAAGCA
GAATGAACTAGGAAATCAGGCTGCTAAGACAAAAATGAGTCAGAAAAAACAAGCGCCTGAAGCTCCTAGTCAAGAATTGG
CAGAAAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTGAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (75-247)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	94.891	100	0.949
endA	Streptococcus pneumoniae D39	94.891	100	0.949
endA	Streptococcus pneumoniae R6	94.891	100	0.949
endA	Streptococcus pneumoniae TIGR4	94.891	100	0.949