Detailed information NTG1126364

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: E0F40_RS09600
• Genome accession: NZ_LR216065
• Coordinates: 1792062..1792886 (-)
• Length: 274 a.a.
• NCBI ID: WP_001036789.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain GPSC18 substr. ST13 isolate 55896440-41bd-11e5-998e-3c4a9275d6c6
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1787062..1797886

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F40_RS09595 (SAMEA3714487_01819)	-	1790440..1791771 (-)	1332	WP_000390043.1	hemolysin family protein	-
E0F40_RS09600 (SAMEA3714487_01820)	endA	1792062..1792886 (-)	825	WP_001036789.1	DNA-entry nuclease EndA	Machinery gene
E0F40_RS09605 (SAMEA3714487_01821)	-	1792925..1793113 (-)	189	WP_001813390.1	DNA-directed RNA polymerase subunit beta	-
E0F40_RS09610 (SAMEA3714487_01822)	murA	1793106..1794389 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
E0F40_RS09615 (SAMEA3714487_01823)	-	1794413..1794643 (-)	231	WP_000250392.1	DUF1146 family protein	-
E0F40_RS09620 (SAMEA3714487_01824)	sepM	1794701..1795738 (-)	1038	WP_000727278.1	SepM family pheromone-processing serine protease	Regulator
E0F40_RS09625 (SAMEA3714487_01825)	coaD	1795722..1796210 (-)	489	WP_001280769.1	pantetheine-phosphate adenylyltransferase	-
E0F40_RS09630 (SAMEA3714487_01826)	rsmD	1796200..1796739 (-)	540	WP_000706963.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
E0F40_RS09635 (SAMEA3714487_01827)	asnA	1796804..1797796 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-

Sequence

Protein

• Length: 274 a.a.
• Molecular weight: 29966.67 Da
• Isoelectric Point: 10.1700

>NTDB_id=1126364 E0F40_RS09600 WP_001036789.1 1792062..1792886(-) (endA) [Streptococcus pneumoniae strain GPSC18 substr. ST13 isolate 55896440-41bd-11e5-998e-3c4a9275d6c6]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLNQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide

• Length: 825 bp

>NTDB_id=1126364 E0F40_RS09600 WP_001036789.1 1792062..1792886(-) (endA) [Streptococcus pneumoniae strain GPSC18 substr. ST13 isolate 55896440-41bd-11e5-998e-3c4a9275d6c6]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGACAGCTAATAGTCCTAAAACCAAGCTTAATCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (75-247)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	98.175	100	0.982
endA	Streptococcus pneumoniae D39	98.175	100	0.982
endA	Streptococcus pneumoniae R6	98.175	100	0.982
endA	Streptococcus pneumoniae TIGR4	98.175	100	0.982