Detailed information NTG1126290

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: E0F31_RS09590
• Genome accession: NZ_LR216064
• Coordinates: 1789568..1790392 (-)
• Length: 274 a.a.
• NCBI ID: WP_054363284.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1784568..1795392

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F31_RS09585 (SAMEA3714520_01805)	-	1787946..1789277 (-)	1332	WP_000390042.1	hemolysin family protein	-
E0F31_RS09590 (SAMEA3714520_01806)	endA	1789568..1790392 (-)	825	WP_054363284.1	DNA-entry nuclease EndA	Machinery gene
E0F31_RS09595 (SAMEA3714520_01807)	-	1790431..1790619 (-)	189	WP_001812859.1	DNA-directed RNA polymerase subunit beta	-
E0F31_RS09600 (SAMEA3714520_01808)	murA	1790612..1791895 (-)	1284	WP_054363285.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
E0F31_RS09605 (SAMEA3714520_01809)	-	1791919..1792149 (-)	231	WP_000250392.1	DUF1146 family protein	-
E0F31_RS09610 (SAMEA3714520_01810)	sepM	1792207..1793244 (-)	1038	WP_000727276.1	SepM family pheromone-processing serine protease	Regulator
E0F31_RS09615 (SAMEA3714520_01811)	coaD	1793228..1793716 (-)	489	WP_050282178.1	pantetheine-phosphate adenylyltransferase	-
E0F31_RS09620 (SAMEA3714520_01812)	rsmD	1793706..1794245 (-)	540	WP_000706963.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
E0F31_RS09625 (SAMEA3714520_01813)	asnA	1794310..1795302 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-

Sequence

Protein

• Length: 274 a.a.
• Molecular weight: 29938.62 Da
• Isoelectric Point: 10.1089

>NTDB_id=1126290 E0F31_RS09590 WP_054363284.1 1789568..1790392(-) (endA) [Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6]
MNKKTRQTLIGLLVLLLLSTGSYYIKQNELGNQAAKTKMSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide

• Length: 825 bp

>NTDB_id=1126290 E0F31_RS09590 WP_054363284.1 1789568..1790392(-) (endA) [Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GAATGAACTAGGAAATCAGGCTGCTAAGACAAAAATGAGTCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCTCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (75-247)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	96.35	100	0.964
endA	Streptococcus pneumoniae D39	96.35	100	0.964
endA	Streptococcus pneumoniae R6	96.35	100	0.964
endA	Streptococcus pneumoniae TIGR4	96.35	100	0.964