Detailed information NTG1122956

Bioinformatically predicted

Overview

• Name: recD2
• Type: Machinery gene
• Locus tag: EL223_RS12290
• Genome accession: NZ_LR134474
• Coordinates: 2512401..2514842 (-)
• Length: 813 a.a.
• NCBI ID: WP_109348317.1
• Uniprot ID: A0A2U3AHV5
• Organism: Kurthia zopfii strain NCTC404
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2507401..2519842

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL223_RS12265 (NCTC404_02574)	ruvX	2507520..2507939 (-)	420	WP_109348322.1	Holliday junction resolvase RuvX	-
EL223_RS12270 (NCTC404_02575)	-	2507939..2508208 (-)	270	WP_109348321.1	IreB family regulatory phosphoprotein	-
EL223_RS12275 (NCTC404_02576)	alaS	2508567..2511221 (-)	2655	WP_126344149.1	alanine--tRNA ligase	-
EL223_RS12280 (NCTC404_02578)	-	2511659..2511976 (+)	318	WP_126344151.1	hypothetical protein	-
EL223_RS12285 (NCTC404_02579)	-	2511971..2512354 (-)	384	WP_126344153.1	hypothetical protein	-
EL223_RS12290 (NCTC404_02580)	recD2	2512401..2514842 (-)	2442	WP_109348317.1	ATP-dependent RecD-like DNA helicase	Machinery gene
EL223_RS12295 (NCTC404_02581)	-	2514859..2515521 (-)	663	WP_109348316.1	tetratricopeptide repeat protein	-
EL223_RS12300 (NCTC404_02582)	mnmA	2515537..2516661 (-)	1125	WP_126344155.1	tRNA 2-thiouridine(34) synthase MnmA	-
EL223_RS12305 (NCTC404_02583)	-	2516684..2517826 (-)	1143	WP_126344157.1	cysteine desulfurase family protein	-
EL223_RS12310 (NCTC404_02584)	cymR	2517842..2518261 (-)	420	WP_109348313.1	cysteine metabolism transcriptional regulator CymR	-
EL223_RS12315 (NCTC404_02585)	-	2518452..2519732 (+)	1281	WP_126344159.1	replication-associated recombination protein A	-

Sequence

Protein

• Length: 813 a.a.
• Molecular weight: 90568.70 Da
• Isoelectric Point: 4.6876

>NTDB_id=1122956 EL223_RS12290 WP_109348317.1 2512401..2514842(-) (recD2) [Kurthia zopfii strain NCTC404]
MTENLSLFADEKLFIVGRPVVSIFHNAENLFSIIKLKIQETNTDYKEKEVIVAGYFPKVVEDSIYRFTGRMTKHPKYGAQ
FKAETFEKEIPATETGVISYLSSDLFPGIGRRTAEIIVKKLGADAIKIIINNPSSLDDIPRLNEEKKETLRLVLQQNLGM
DRIMIKLGEWGFGAQLAIKIYQLYLEDTIQLLQENPYRLIADVDGVGFQRADDLGEILGIGGSHPSRIEAAVIHIVNQAS
LSDGHTFIEAQQVIPQAKAILEQSQNVVISFEEISEAIIRLGEEGLLCGEETRLYIPSLYYSEVGIASKILQLKEKNEEQ
SAFPVSEIRKWIGDAEERFEVTYAKTQIKAIETAINSAVMILTGGPGTGKTTVVRGIVDVFAELHGLSLDPKEYSKKDEE
FPIILVAPTGRAAKRLSESTGLPAQTIHRLLGFNGQDKEEESEREIEGKLLIVDEMSMVDTWLAHQLLRALNDKCQIVFV
GDQDQLPPVGPGQVLKDLLASKAIPTVELSDVYRQADGSSIIELAHQMKMGQTPTNLTEKTSDRSFIPAYANQVPSVVQQ
VIGSALNKGFSIHDVQVLAPMYRGDAGIDALNKLIQEFVNPKKNAKTKEIQFGETTYRIGDKVLQLVNQPNSNVFNGDMG
EIISILKAKETTEKQDVMVISFDGIEVTYERSDLNQITLAYCCSIHKSQGSEFPMVIMPVVSGYSKMLRKNLLYTGLTRA
KNFLILCGEPETFLRGIQNDSDILRQTSLSSRLLESSDEIAEKEQPADQEIPEKPATFALTMDNFMQIPPMIGMDRIKPT
DFLVDEQQELLDT

Nucleotide

• Length: 2442 bp

>NTDB_id=1122956 EL223_RS12290 WP_109348317.1 2512401..2514842(-) (recD2) [Kurthia zopfii strain NCTC404]
TTGACTGAAAATCTTTCACTATTTGCAGATGAAAAATTATTCATAGTGGGTCGACCTGTCGTCTCTATTTTTCATAATGC
TGAGAATTTATTTTCCATTATAAAGCTGAAAATTCAAGAGACGAATACGGATTATAAAGAAAAAGAAGTGATAGTTGCAG
GATATTTTCCAAAGGTAGTAGAGGATTCGATTTATCGATTTACTGGCAGAATGACGAAACATCCTAAATACGGCGCGCAA
TTTAAGGCGGAGACATTTGAAAAAGAGATTCCAGCTACTGAAACGGGCGTAATCTCTTATTTAAGTAGTGATTTATTCCC
TGGTATTGGACGTAGAACGGCTGAGATTATCGTCAAAAAACTAGGGGCAGATGCCATTAAAATCATCATTAATAATCCTT
CATCTTTGGATGATATTCCACGATTAAACGAAGAGAAAAAAGAAACATTACGCCTTGTTTTACAACAAAACTTAGGTATG
GACCGTATAATGATCAAATTAGGGGAATGGGGTTTTGGTGCGCAACTGGCAATCAAAATCTATCAGCTTTATTTAGAGGA
TACGATTCAATTATTACAAGAAAATCCGTATAGATTAATTGCAGATGTAGATGGTGTTGGATTCCAACGTGCAGATGACT
TAGGCGAGATATTAGGGATTGGCGGTTCGCATCCGAGTCGAATCGAAGCGGCTGTTATTCATATCGTCAATCAAGCTTCA
TTGTCAGATGGGCATACATTTATTGAAGCGCAGCAAGTGATTCCGCAGGCGAAAGCGATTTTGGAGCAAAGTCAAAACGT
CGTCATTTCCTTTGAAGAAATTTCAGAAGCGATTATTCGTTTAGGAGAAGAAGGATTACTATGTGGTGAGGAAACTCGCT
TATACATTCCATCTCTTTACTATTCGGAAGTCGGGATCGCTTCGAAAATATTGCAACTGAAAGAAAAAAATGAAGAACAA
TCGGCATTCCCAGTATCAGAAATCCGCAAATGGATTGGTGATGCGGAAGAACGATTCGAAGTGACGTATGCCAAGACGCA
AATTAAAGCGATTGAGACAGCTATTAATAGTGCGGTTATGATTTTAACGGGTGGTCCAGGTACGGGGAAAACAACCGTTG
TTCGGGGAATTGTCGATGTATTTGCGGAGTTACATGGCTTATCGCTCGATCCGAAAGAATATAGTAAAAAAGACGAAGAA
TTCCCAATCATTTTAGTTGCGCCAACTGGTCGTGCAGCGAAGCGATTAAGTGAGTCTACAGGATTACCTGCACAGACGAT
TCATCGACTACTTGGATTTAATGGACAAGATAAGGAAGAAGAATCAGAACGTGAAATTGAAGGGAAATTATTAATTGTTG
ATGAAATGTCGATGGTTGATACGTGGTTAGCACATCAACTTTTAAGAGCGCTTAACGATAAATGTCAAATCGTATTTGTC
GGGGATCAGGATCAATTACCACCTGTTGGCCCTGGCCAAGTATTGAAAGATTTACTCGCTTCAAAAGCGATTCCTACTGT
CGAATTAAGCGATGTTTATCGCCAAGCAGATGGTTCATCAATCATTGAATTAGCGCATCAGATGAAAATGGGGCAAACAC
CAACGAATTTAACAGAGAAAACGAGCGATCGTTCATTTATTCCTGCCTATGCGAACCAAGTGCCAAGCGTAGTCCAGCAA
GTCATTGGATCGGCATTGAATAAAGGATTCTCTATTCATGATGTGCAAGTGCTAGCGCCGATGTACCGTGGTGATGCAGG
GATTGATGCCTTGAATAAATTGATTCAAGAATTCGTCAATCCGAAGAAAAATGCGAAAACGAAGGAAATTCAATTTGGCG
AAACAACATACCGAATTGGGGATAAAGTACTGCAACTTGTCAATCAACCAAATAGTAATGTCTTTAATGGTGATATGGGT
GAAATCATCTCAATTTTGAAAGCGAAGGAAACAACGGAGAAGCAAGATGTTATGGTCATTTCATTTGATGGAATTGAAGT
GACATATGAGCGATCAGACTTGAATCAGATTACACTGGCTTATTGCTGTTCGATTCATAAATCGCAAGGTAGTGAATTTC
CAATGGTCATTATGCCGGTCGTAAGTGGCTATTCAAAAATGCTTCGGAAAAATCTTTTATATACGGGTTTAACGAGAGCT
AAAAACTTCCTGATTCTATGCGGGGAGCCTGAAACATTTTTAAGAGGTATTCAAAATGATTCAGATATTCTAAGACAAAC
GAGCTTATCGAGTCGATTACTTGAATCTTCCGATGAAATTGCCGAAAAGGAACAACCAGCCGATCAGGAAATTCCGGAGA
AGCCAGCCACATTTGCTTTAACGATGGATAATTTCATGCAAATTCCACCGATGATTGGAATGGATCGCATTAAGCCTACA
GATTTTTTAGTAGATGAGCAACAGGAATTATTAGATACTTAG

Domains

Predicted by InterproScan.

• ATP-dependent RecD-like DNA helicase SH3 domain (SH3_13) (591-659)

• Helix-hairpin-helix containing domain (HHH_RecD2) (159-247)

• UvrD-like helicase C-terminal domain (UvrD_C_2) (680-727)

• AAA domain (AAA_30) (343-547)

3D structure

• AlphaFold DB: A0A2U3AHV5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
recD2	Bacillus subtilis subsp. subtilis str. 168	52.618	98.647	0.519