Detailed information NTG1121272

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: EL136_RS04905
• Genome accession: NZ_LR134317
• Coordinates: 1017372..1018250 (-)
• Length: 292 a.a.
• NCBI ID: WP_154803934.1
• Uniprot ID: A0A7Z8ZX01
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC6180
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1012372..1023250

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL136_RS04895 (NCTC6180_01008)	pheT	1012825..1015230 (-)	2406	WP_154803933.1	phenylalanine--tRNA ligase subunit beta	-
EL136_RS04900 (NCTC6180_01009)	pheS	1015420..1016463 (-)	1044	WP_012678105.1	phenylalanine--tRNA ligase subunit alpha	-
EL136_RS10990	-	1017200..1017358 (-)	159	WP_014622728.1	hypothetical protein	-
EL136_RS04905 (NCTC6180_01010)	endA	1017372..1018250 (-)	879	WP_154803934.1	DNA/RNA non-specific endonuclease	Machinery gene
EL136_RS04910 (NCTC6180_01011)	-	1018282..1018470 (-)	189	WP_012678107.1	DNA-directed RNA polymerase subunit beta	-
EL136_RS04915 (NCTC6180_01012)	murA	1018474..1019745 (-)	1272	WP_154803935.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
EL136_RS04920 (NCTC6180_01013)	-	1019809..1020045 (-)	237	WP_012678109.1	DUF1146 family protein	-
EL136_RS04925 (NCTC6180_01014)	-	1020179..1020595 (-)	417	WP_012678110.1	F0F1 ATP synthase subunit epsilon	-
EL136_RS04930 (NCTC6180_01015)	atpD	1020608..1022014 (-)	1407	WP_021320644.1	F0F1 ATP synthase subunit beta	-
EL136_RS04935 (NCTC6180_01016)	-	1022182..1023057 (-)	876	WP_012515431.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 292 a.a.
• Molecular weight: 31850.92 Da
• Isoelectric Point: 10.2448

>NTDB_id=1121272 EL136_RS04905 WP_154803934.1 1017372..1018250(-) (endA) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
MIKKKKDIRLLNAFLALLLVLGTGYLAGHDDLAADNPIKQVYQRIFGSDPQQAGLPKASRDWDTPSKALADSVMTATIKQ
QLGDVITWNGTGAYIINHNKTTLNAKVASLPYANNKTKLVQGQSVPTVANALLTKSTRQYQKRNDTGNGYSSWKPAGWHQ
VQGLKGRYSHAVDRGHLLGYALVGGLKGFDASMANPSNIATQTAWANQAANERSTGQNYYETKIRRALDSNKRVRYRVTL
LYEGNNLLASGSHLEAKSSDGSLEFNVFIPNVQAGLQIDYQTGQITVASSQP

Nucleotide

• Length: 879 bp

>NTDB_id=1121272 EL136_RS04905 WP_154803934.1 1017372..1018250(-) (endA) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
ATGATCAAAAAGAAGAAAGACATTAGGCTGCTTAATGCCTTTTTAGCGCTGTTGCTTGTTCTTGGAACAGGTTATTTGGC
AGGACATGATGACCTAGCAGCTGATAATCCGATCAAGCAGGTCTACCAAAGGATTTTTGGCTCTGACCCGCAGCAAGCCG
GGCTACCAAAGGCAAGCCGAGACTGGGACACTCCCTCCAAGGCCTTGGCAGATTCGGTCATGACAGCCACCATCAAACAG
CAATTAGGTGATGTGATTACTTGGAATGGCACTGGTGCCTATATCATTAACCATAATAAAACGACGCTAAATGCAAAGGT
AGCCAGTCTCCCCTATGCCAATAATAAAACAAAGCTGGTACAAGGGCAAAGCGTTCCTACCGTAGCCAATGCCCTGCTAA
CCAAGTCAACCCGACAATATCAGAAGCGCAATGACACTGGAAATGGCTATAGCTCATGGAAGCCTGCTGGCTGGCATCAG
GTTCAAGGATTAAAGGGAAGATACAGTCACGCAGTAGATAGAGGACACCTCCTGGGCTATGCACTTGTTGGTGGGCTAAA
GGGCTTTGATGCCTCAATGGCTAATCCCAGTAATATTGCTACTCAAACCGCATGGGCCAATCAAGCAGCCAACGAGCGAT
CAACCGGACAAAACTATTATGAAACAAAGATTCGCAGAGCCCTAGATAGCAATAAGCGTGTCCGCTATCGTGTAACTTTG
CTTTATGAGGGAAATAATCTCTTAGCAAGCGGCAGTCATCTTGAGGCAAAGTCATCAGATGGTAGCTTAGAATTTAACGT
CTTTATCCCTAATGTACAGGCTGGATTACAGATTGATTATCAAACAGGTCAGATCACTGTAGCTTCTTCCCAGCCTTAG

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (116-247)

3D structure

• AlphaFold DB: A0A7Z8ZX01

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	67.257	77.397	0.521
endA	Streptococcus pneumoniae D39	67.257	77.397	0.521
endA	Streptococcus pneumoniae R6	67.257	77.397	0.521
endA	Streptococcus pneumoniae TIGR4	67.257	77.397	0.521