Detailed information NTG1121242

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: EL139_RS10080
• Genome accession: NZ_LR134316
• Coordinates: 2043889..2044755 (-)
• Length: 288 a.a.
• NCBI ID: WP_111716020.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 2038889..2049755

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL139_RS10060 (NCTC6181_02068)	-	2039079..2039465 (-)	387	WP_111716031.1	DUF1722 domain-containing protein	-
EL139_RS10065 (NCTC6181_02069)	-	2039458..2039835 (-)	378	WP_111716028.1	OsmC family protein	-
EL139_RS10070 (NCTC6181_02070)	pheT	2039948..2042353 (-)	2406	WP_111716026.1	phenylalanine--tRNA ligase subunit beta	-
EL139_RS10075 (NCTC6181_02071)	pheS	2042563..2043606 (-)	1044	WP_111716023.1	phenylalanine--tRNA ligase subunit alpha	-
EL139_RS10080 (NCTC6181_02073)	endA	2043889..2044755 (-)	867	WP_111716020.1	DNA/RNA non-specific endonuclease	Machinery gene
EL139_RS10085 (NCTC6181_02074)	-	2044791..2044979 (-)	189	WP_111716018.1	DNA-directed RNA polymerase subunit beta	-
EL139_RS10090 (NCTC6181_02075)	murA	2044983..2046254 (-)	1272	WP_111716016.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
EL139_RS10095 (NCTC6181_02076)	-	2046319..2046555 (-)	237	WP_277997757.1	DUF1146 family protein	-
EL139_RS10100 (NCTC6181_02077)	-	2046884..2047300 (-)	417	WP_003050138.1	F0F1 ATP synthase subunit epsilon	-
EL139_RS10105 (NCTC6181_02078)	atpD	2047313..2048719 (-)	1407	WP_111716013.1	F0F1 ATP synthase subunit beta	-

Sequence

Protein

• Length: 288 a.a.
• Molecular weight: 31916.95 Da
• Isoelectric Point: 10.0753

>NTDB_id=1121242 EL139_RS10080 WP_111716020.1 2043889..2044755(-) (endA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181]
MLTRKKRKRVLNSFLLILLVLGSSYLAKSDFIASNHPIKQIYRTVLGDKGESSSESKEVYSEVPTEALSASVLTKSIKEQ
LGSNIEWNGAGAYIINRNKTDLNASVASLPYANNETKWVQGQKVPTRANALLTKSTRQYQNRYQTDNAYRTFKPAGWHQL
HHLKGNYDHAVDRGHLLGYALVGGLKGFDASTSNPDNIATQLSWANQADKPYSTGQNYYEGLVRRALDKGKRVRYRVTLL
YDGDNLLASGSQLEAKSADGSLAFNVFVPNVQAGLTVDYRTGQIVINP

Nucleotide

• Length: 867 bp

>NTDB_id=1121242 EL139_RS10080 WP_111716020.1 2043889..2044755(-) (endA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181]
ATGTTAACAAGGAAAAAACGAAAAAGGGTGCTTAATTCCTTCTTATTGATTTTGTTAGTGTTGGGGTCTAGTTACCTTGC
TAAGAGTGATTTCATAGCTAGCAACCATCCTATTAAGCAAATTTATCGTACCGTTTTGGGAGATAAGGGTGAATCATCAT
CAGAATCAAAAGAAGTCTATAGTGAGGTTCCCACAGAAGCCCTATCGGCTTCTGTCTTAACCAAATCCATTAAGGAACAA
TTAGGTTCCAATATTGAATGGAATGGAGCAGGCGCTTATATTATCAACCGGAACAAAACAGATTTAAACGCAAGCGTAGC
CAGTCTGCCCTATGCTAATAATGAAACCAAATGGGTCCAAGGACAAAAGGTTCCTACTAGAGCTAATGCCTTACTTACTA
AGTCGACACGACAGTATCAAAATCGCTATCAAACGGACAATGCTTATCGTACCTTCAAGCCTGCTGGTTGGCACCAATTA
CATCACTTAAAAGGAAATTATGATCATGCAGTTGATAGAGGACATTTGCTAGGTTATGCTTTAGTTGGTGGACTGAAAGG
TTTTGATGCTTCTACCAGTAATCCTGATAATATTGCCACTCAACTAAGTTGGGCCAATCAAGCAGATAAACCCTATTCGA
CAGGTCAAAATTACTATGAAGGATTAGTACGTCGTGCATTGGATAAGGGCAAAAGGGTCCGTTATCGTGTTACCTTGCTT
TATGATGGTGATAACCTGTTAGCCAGTGGTAGCCAGTTAGAGGCCAAATCTGCCGATGGGAGTTTAGCATTTAACGTGTT
TGTTCCAAATGTCCAAGCAGGGCTGACGGTTGATTATCGAACAGGACAGATTGTCATCAATCCCTAG

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (119-246)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	62.338	80.208	0.5
endA	Streptococcus pneumoniae D39	62.338	80.208	0.5
endA	Streptococcus pneumoniae R6	62.338	80.208	0.5
endA	Streptococcus pneumoniae TIGR4	62.338	80.208	0.5