Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   EL092_RS03860 Genome accession   NZ_LR134291
Coordinates   805438..806277 (+) Length   279 a.a.
NCBI ID   WP_012000227.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC7868     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 800438..811277
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL092_RS03835 (NCTC7868_00761) tuf 801301..802497 (+) 1197 WP_009754926.1 elongation factor Tu -
  EL092_RS03840 (NCTC7868_00762) tpiA 802771..803529 (+) 759 WP_012000225.1 triose-phosphate isomerase -
  EL092_RS03845 (NCTC7868_00763) - 803659..803892 (+) 234 WP_041789607.1 DUF1146 family protein -
  EL092_RS03850 (NCTC7868_00764) murA 803932..805212 (+) 1281 WP_012000226.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  EL092_RS03855 (NCTC7868_00765) - 805205..805393 (+) 189 WP_020992673.1 DNA-directed RNA polymerase subunit beta -
  EL092_RS03860 (NCTC7868_00766) endA 805438..806277 (+) 840 WP_012000227.1 DNA/RNA non-specific endonuclease Machinery gene
  EL092_RS03865 (NCTC7868_00767) - 806493..807194 (-) 702 WP_012000228.1 alpha/beta hydrolase-fold protein -
  EL092_RS03870 (NCTC7868_00768) - 807175..808203 (-) 1029 WP_041789612.1 ABC transporter substrate-binding protein -
  EL092_RS03875 (NCTC7868_00769) - 808348..809103 (-) 756 WP_012000231.1 ABC transporter ATP-binding protein -
  EL092_RS03880 (NCTC7868_00770) - 809105..810151 (-) 1047 WP_012000232.1 FecCD family ABC transporter permease -
  EL092_RS10825 - 810444..810551 (+) 108 Protein_748 DNA-entry nuclease -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 30866.60 Da        Isoelectric Point: 10.0956

>NTDB_id=1120354 EL092_RS03860 WP_012000227.1 805438..806277(+) (endA) [Streptococcus gordonii strain NCTC7868]
MKKKQEEKLFQSIVGLILALVLIAGANYFSNHQNQDKIKSNPQVQRTGRRDISTPEQALSQSVLTDSVRKQLKGNIEWNQ
AGAFIINGNKTDLNADIASQPYAQNQTKSVQGQLVPIIGNALLSKQTRQYKNREETGNGTTSWVPAGWHQVRNLSGDFNH
AVDRGHLLAYSIVGGLKNFDASTSNPENIAVQTAWANQANSPSSTGQNFYESLIRKALDKKKRVRYRVTLIYANPDDLIA
VGSHLEAKSSDGSLEFNVFVPNVQTGIRINYRTGEVTVE

Nucleotide


Download         Length: 840 bp        

>NTDB_id=1120354 EL092_RS03860 WP_012000227.1 805438..806277(+) (endA) [Streptococcus gordonii strain NCTC7868]
ATGAAGAAGAAACAAGAAGAGAAACTCTTTCAAAGCATAGTAGGACTGATTCTGGCACTTGTTCTGATAGCTGGTGCTAA
TTATTTCTCAAACCATCAGAATCAGGATAAGATAAAGTCTAATCCACAGGTTCAAAGAACAGGAAGAAGGGATATCTCAA
CCCCCGAGCAAGCACTATCTCAGAGTGTGCTGACTGATTCTGTTCGCAAGCAATTAAAAGGCAACATAGAATGGAATCAG
GCAGGTGCATTTATTATTAATGGCAACAAGACAGACCTGAATGCTGATATTGCCAGTCAGCCTTATGCACAAAATCAGAC
AAAGTCAGTTCAGGGACAGTTAGTACCAATAATTGGGAATGCTCTGCTTTCTAAACAGACTAGACAATACAAAAATCGAG
AAGAAACCGGAAACGGAACGACAAGTTGGGTTCCTGCTGGCTGGCATCAAGTGAGAAATCTTAGTGGAGATTTTAATCAT
GCAGTTGATCGAGGCCATTTATTAGCTTATTCTATAGTCGGAGGCTTAAAGAACTTCGATGCTTCTACAAGTAACCCAGA
GAATATCGCTGTCCAAACGGCTTGGGCAAATCAGGCAAACAGTCCTTCATCTACTGGGCAAAATTTTTATGAAAGCTTGA
TTCGGAAGGCTTTGGATAAAAAGAAGAGAGTTCGTTATCGGGTAACCTTGATTTATGCTAATCCTGATGACTTGATAGCA
GTAGGCTCTCATTTAGAAGCAAAGTCCAGCGACGGAAGCCTCGAGTTTAATGTCTTCGTTCCAAATGTTCAAACCGGGAT
TCGTATCAACTATAGAACTGGAGAAGTAACAGTAGAGTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(82-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

68.304

80.287

0.548
  endA Streptococcus pneumoniae D39

68.304

80.287

0.548
  endA Streptococcus pneumoniae R6

68.304

80.287

0.548
  endA Streptococcus pneumoniae TIGR4

68.304

80.287

0.548

Multiple sequence alignment