Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   EL087_RS02990 Genome accession   NZ_LR134288
Coordinates   610907..611758 (+) Length   283 a.a.
NCBI ID   WP_003040412.1    Uniprot ID   A0AAD2T988
Organism   Streptococcus milleri strain NCTC11169     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 605907..616758
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL087_RS02960 (NCTC11169_00597) - 606129..607007 (+) 879 WP_003030484.1 F0F1 ATP synthase subunit gamma -
  EL087_RS02965 (NCTC11169_00598) atpD 607042..608448 (+) 1407 WP_126406760.1 F0F1 ATP synthase subunit beta -
  EL087_RS02970 (NCTC11169_00599) - 608459..608878 (+) 420 WP_003025266.1 F0F1 ATP synthase subunit epsilon -
  EL087_RS02975 (NCTC11169_00600) - 608982..609212 (+) 231 WP_080564559.1 DUF1146 family protein -
  EL087_RS02980 (NCTC11169_00601) murA 609250..610530 (+) 1281 WP_126406762.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  EL087_RS02985 (NCTC11169_00602) - 610523..610699 (+) 177 WP_003040295.1 DNA-directed RNA polymerase subunit beta -
  EL087_RS02990 (NCTC11169_00603) endA 610907..611758 (+) 852 WP_003040412.1 DNA/RNA non-specific endonuclease Machinery gene
  EL087_RS02995 (NCTC11169_00604) - 612048..613784 (+) 1737 WP_126406764.1 ABC transporter ATP-binding protein -
  EL087_RS03000 (NCTC11169_00605) - 613798..615570 (+) 1773 WP_126406766.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 283 a.a.        Molecular weight: 31119.84 Da        Isoelectric Point: 10.4363

>NTDB_id=1120256 EL087_RS02990 WP_003040412.1 610907..611758(+) (endA) [Streptococcus milleri strain NCTC11169]
MARKKSNQKVAQSVAGVFLALVLALGGYSFSNYHNHSSTKHSDSTAINRSIRKNYAAPSQELAQSVLTESVKRQLKGKIE
WNGAGAFIVNENKNDLDAKVGSIPYADNKTKLVRGRTVPTVANALLSKTTRQYRSREETGNGSTTWTPAGWHQVKHLSGE
YNHAVDRGHLLGYALIGNLKGFDASTSNPKNIAVQTAWANQANTSHSTGQNFYETKVRKALDKNKRVRYRVTLIYANEQD
LVPVGSHIEAKSSDSSLEMNVFVPNVQTGLRLNYQTGEVTVTN

Nucleotide


Download         Length: 852 bp        

>NTDB_id=1120256 EL087_RS02990 WP_003040412.1 610907..611758(+) (endA) [Streptococcus milleri strain NCTC11169]
ATGGCGAGAAAGAAATCCAACCAGAAAGTAGCGCAAAGTGTAGCAGGCGTATTTCTTGCACTTGTTCTTGCGCTGGGAGG
TTATTCTTTTAGCAATTATCATAATCATAGCAGTACGAAGCATTCTGACAGCACTGCTATTAACAGGAGTATTCGTAAGA
ATTATGCAGCACCCAGTCAAGAATTAGCACAGAGCGTTTTAACAGAATCTGTCAAACGACAGCTCAAAGGGAAAATCGAG
TGGAATGGCGCAGGGGCTTTTATTGTCAATGAGAATAAAAATGATTTAGATGCTAAAGTGGGAAGTATTCCTTATGCGGA
TAATAAGACAAAATTGGTCAGAGGTCGAACTGTTCCAACGGTAGCAAATGCTCTTTTATCCAAAACAACTCGCCAATATA
GAAGTCGTGAAGAAACAGGAAATGGCTCCACGACTTGGACACCTGCTGGTTGGCATCAAGTCAAGCATTTATCAGGTGAA
TACAACCATGCAGTTGACCGAGGACATTTGTTGGGTTATGCTTTGATTGGTAACTTGAAAGGGTTTGATGCTTCGACCAG
TAACCCGAAAAATATAGCTGTGCAAACAGCTTGGGCTAATCAAGCAAATACTAGTCATTCTACGGGTCAAAATTTCTATG
AAACAAAGGTTCGCAAGGCACTAGACAAGAATAAACGAGTTCGGTATCGGGTGACTTTGATTTATGCTAATGAACAGGAT
TTAGTGCCAGTTGGTTCGCATATTGAAGCTAAATCAAGCGATAGTAGCTTGGAAATGAATGTCTTTGTTCCCAACGTACA
GACAGGACTTCGGCTAAATTATCAAACAGGAGAAGTGACCGTTACCAACTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(114-281)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

76.991

79.859

0.615
  endA Streptococcus pneumoniae D39

76.991

79.859

0.615
  endA Streptococcus pneumoniae R6

76.991

79.859

0.615
  endA Streptococcus pneumoniae TIGR4

76.991

79.859

0.615

Multiple sequence alignment