Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   EL100_RS00115 Genome accession   NZ_LR134285
Coordinates   18382..19194 (-) Length   270 a.a.
NCBI ID   WP_185946472.1    Uniprot ID   -
Organism   Streptococcus australis strain NCTC3168     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 13382..24194
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL100_RS00095 (NCTC3168_00019) - 14259..15131 (-) 873 WP_126404024.1 XRE/MutR family transcriptional regulator -
  EL100_RS00100 (NCTC3168_00020) - 15132..17039 (-) 1908 WP_126404023.1 ABC-F family ATP-binding cassette domain-containing protein -
  EL100_RS00105 (NCTC3168_00021) - 17122..17493 (-) 372 WP_126404022.1 hypothetical protein -
  EL100_RS00110 (NCTC3168_00022) - 17496..18215 (-) 720 WP_126404021.1 matrixin family metalloprotease -
  EL100_RS00115 (NCTC3168_00023) endA 18382..19194 (-) 813 WP_185946472.1 DNA/RNA non-specific endonuclease Machinery gene
  EL100_RS00120 (NCTC3168_00024) - 19299..19487 (-) 189 WP_126404019.1 DNA-directed RNA polymerase subunit beta -
  EL100_RS00125 (NCTC3168_00025) murA 19477..20760 (-) 1284 WP_023026629.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  EL100_RS00130 (NCTC3168_00026) - 20827..21057 (-) 231 WP_040803274.1 DUF1146 family protein -
  EL100_RS00135 (NCTC3168_00027) - 21144..21563 (-) 420 WP_006596621.1 F0F1 ATP synthase subunit epsilon -
  EL100_RS00140 (NCTC3168_00028) atpD 21577..22983 (-) 1407 WP_006596622.1 F0F1 ATP synthase subunit beta -
  EL100_RS00145 (NCTC3168_00029) - 23072..23953 (-) 882 WP_006596944.1 F0F1 ATP synthase subunit gamma -

Sequence

Protein


Download         Length: 270 a.a.        Molecular weight: 29646.22 Da        Isoelectric Point: 8.9578

>NTDB_id=1120133 EL100_RS00115 WP_185946472.1 18382..19194(-) (endA) [Streptococcus australis strain NCTC3168]
MKKSGQTLLGLVVAVALSIGGYYFSQPQPVASHSQVQTVVTSSQEATPSKELAESVLTDSVRAKLGKNIQWNEAGAFIIN
QNKTNLDADVASLPYADTKTKTVKGREIPTVANALMTKATRQYQKREQTDIDWAPAGWHQVTNLAGEYDHAVDRGHLLGY
ALIGNLDGFDASMTNPKNIAVQTAWANQARDSFSTGQNYYETLVRKALDKNKRVRYRVTLYYASDEDLVPVGSQIEAKSS
DGSLEFNVFVPNVQSGISLDYRTGKVTVHR

Nucleotide


Download         Length: 813 bp        

>NTDB_id=1120133 EL100_RS00115 WP_185946472.1 18382..19194(-) (endA) [Streptococcus australis strain NCTC3168]
ATGAAAAAATCGGGACAAACCCTACTGGGCTTGGTGGTGGCAGTAGCCCTCTCCATCGGTGGCTATTATTTTAGTCAACC
CCAGCCAGTCGCAAGTCACTCTCAGGTTCAAACGGTTGTTACTTCGAGTCAAGAAGCAACCCCGAGTAAGGAACTAGCGG
AGAGTGTTCTGACAGATAGTGTTCGAGCTAAACTAGGAAAGAACATTCAATGGAACGAAGCGGGCGCTTTTATCATTAAT
CAAAACAAAACCAATCTGGATGCGGATGTTGCGAGTCTCCCTTATGCAGATACCAAGACAAAGACTGTAAAAGGAAGAGA
GATCCCAACAGTTGCCAACGCTTTGATGACCAAGGCGACTCGTCAATACCAAAAGAGAGAACAGACGGACATAGATTGGG
CTCCCGCTGGCTGGCACCAAGTAACCAATTTAGCTGGGGAATATGACCATGCGGTTGATCGGGGACACCTTCTCGGCTAT
GCCTTGATTGGCAACTTAGATGGATTTGATGCCTCGATGACGAATCCTAAAAATATTGCGGTTCAAACAGCTTGGGCCAA
TCAAGCGCGTGATAGTTTTTCAACGGGACAAAATTACTATGAAACCCTTGTTCGCAAGGCCCTAGACAAAAATAAACGGG
TCCGTTATCGGGTGACACTCTACTATGCATCGGATGAAGATTTAGTACCAGTTGGTAGTCAGATTGAAGCGAAATCCAGC
GATGGTAGTCTAGAGTTTAATGTCTTTGTTCCGAATGTCCAGAGTGGGATTAGTTTGGATTATCGTACTGGAAAAGTAAC
AGTGCATCGCTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

66.544

100

0.67
  endA Streptococcus pneumoniae D39

66.544

100

0.67
  endA Streptococcus pneumoniae R6

66.544

100

0.67
  endA Streptococcus pneumoniae TIGR4

66.544

100

0.67

Multiple sequence alignment